Peer-reviewed Articles - Medicine

53 downloads
149 views

Background Skin cancer incidence has increased over the last years, becoming a major public health problem. Objective To describe the awareness, behavior and attitudes concerning sun exposure among beachgoers in the northern coast of Peru. Methods We conducted...

["Dermatology","Epidemiology","Public Health"]
doi:10.7717/peerj.6189
33 downloads
126 views

Secreted Frizzled-related Protein 4 (sFRP4) belongs to Wnt inhibitors. Previously, we reported that sFRP4 inhibited the differentiation of melanocyte. Here, by using of immunostaining, we showed that sFRP4 is expressed in both human and mouse hair follicles, especially...

["Cell Biology","Dermatology"]
doi:10.7717/peerj.6153
1 citation
100 downloads
503 views

Background Pemphigus is a common life-threatening, autoimmune bullous disease effecting both cutaneous and mucous membranes. Previous diagnosis of pemphigus is based on clinical presentations, histopathology, immunofluorescence and enzyme-linked immunosorbent assay....

["Allergy and Clinical Immunology","Dermatology","Immunology"]
doi:10.7717/peerj.5388
147 downloads
524 views

Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor skin to achieve...

["Bioengineering","Biotechnology","Dermatology"]
doi:10.7717/peerj.4815
2 citations
230 downloads
687 views

Background Vitexin is a kind of lignan compound which has been shown to possess a variety of pharmacological effects, such as anti-inflammatory, anti-oxidative and anti-cancer activities. However the effect of vitexin on hair regeneration has not been elaborated....

["Cell Biology","Molecular Biology","Dermatology","Pharmacology"]
doi:10.7717/peerj.4737
1 citation
127 downloads
565 views

Background Acitretin is a second-generation synthetic retinoid, and is widely used for treating the severe psoriasis vulgaris. However, it should be chosen with caution for its cardiovascular risk, and it is reported that acitretin may increase the serum lipids....

["Dermatology","Pharmacology","Medical Genetics"]
doi:10.7717/peerj.4637
199 downloads
897 views

Dermal papilla (DP) plays important roles in hair follicle regeneration. Long-term culture of mouse DP cells can provide enough cells for research and application of DP cells. We optimized the culture strategy for DP cells from three dimensions: stepwise dissection,...

["Biotechnology","Cell Biology","Dermatology"]
doi:10.7717/peerj.4306
184 downloads
1,083 views

Background Early detection and treatment are the most important elements in reducing the incidence of melanoma deaths. Acquired melanocytic naevi (AMN) are well-known precursors of melanoma but most of our knowledge on the clinico-dermoscopic phenotypes of AMN...

["Dermatology"]
doi:10.7717/peerj.4168
4 citations
473 downloads
1,715 views

Background Skin microbiome varies from person to person due to a combination of various factors, including age, biogeography, sex, cosmetics and genetics. Many skin disorders appear to be related to the resident microflora, yet databases of facial skin microbiome...

["Microbiology","Dermatology"]
doi:10.7717/peerj.4084
3 citations
182 downloads
884 views

Aims Periodontitis and psoriatic disease, including psoriasis (PS) and psoriatic arthritis (PsA), share the common risk factors and co-morbidities. However, the risk of periodontitis in patients with psoriatic disease still needs further investigation. This study...

["Dentistry","Dermatology","Epidemiology","Public Health","Rheumatology"]
doi:10.7717/peerj.4064
211 downloads
1,014 views

A study was carried out to assess the effect of Stress Coat® on slime production in goldfish (Carassius auratus) and koi (Cyprinus carpio). The study also investigated histological changes that might be associated with slime producing cells, and wound healing in...

["Aquaculture, Fisheries and Fish Science","Veterinary Medicine","Zoology","Dermatology"]
doi:10.7717/peerj.3759
3 citations
586 downloads
2,502 views

Identification of appropriate reference genes (RGs) is critical to accurate data interpretation in quantitative real-time PCR (qPCR) experiments. In this study, we have utilised next generation RNA sequencing (RNA-seq) to analyse the transcriptome of a panel of...

["Genomics","Molecular Biology","Dermatology","Oncology","Medical Genetics"]
doi:10.7717/peerj.3631
1 citation
538 downloads
1,102 views

Background Quercus infectoria G. Olivier (Fagaceae) nutgalls have been widely employed in traditional Asian medicine for several treatments, especially wounds and skin disorders. However, the effects of this plant on wound healing have not yet been clearly elucidated....

["Dermatology","Diabetes and Endocrinology","Evidence Based Medicine"]
doi:10.7717/peerj.3608
197 downloads
1,127 views

Background 2′–4′ Dinitrofluorobenzene (DNFB) induced contact hypersensitivity is an established model of contact sensitivity and leukocyte migration. Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) deficient mice were used to examine the role of PECAM-1...

["Cell Biology","Dermatology","Immunology"]
doi:10.7717/peerj.3555
2 citations
168 downloads
893 views

Background There is currently no study that has evaluated the differences in epidemiological and clinical characteristics among rosacea patients according to different facial sites. Methods Clinical and demographic data were obtained from 586 rosacea patients....

["Dermatology","Epidemiology","Pharmacology"]
doi:10.7717/peerj.3527

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