Peer-reviewed Articles - Medicine

61 downloads
187 views

Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor skin to achieve...

["Bioengineering","Biotechnology","Dermatology"]
doi:10.7717/peerj.4815
85 downloads
302 views

Background Vitexin is a kind of lignan compound which has been shown to possess a variety of pharmacological effects, such as anti-inflammatory, anti-oxidative and anti-cancer activities. However the effect of vitexin on hair regeneration has not been elaborated....

["Cell Biology","Molecular Biology","Dermatology","Pharmacology"]
doi:10.7717/peerj.4737
87 downloads
291 views

Background Acitretin is a second-generation synthetic retinoid, and is widely used for treating the severe psoriasis vulgaris. However, it should be chosen with caution for its cardiovascular risk, and it is reported that acitretin may increase the serum lipids....

["Dermatology","Pharmacology","Medical Genetics"]
doi:10.7717/peerj.4637
110 downloads
511 views

Dermal papilla (DP) plays important roles in hair follicle regeneration. Long-term culture of mouse DP cells can provide enough cells for research and application of DP cells. We optimized the culture strategy for DP cells from three dimensions: stepwise dissection,...

["Biotechnology","Cell Biology","Dermatology"]
doi:10.7717/peerj.4306
114 downloads
684 views

Background Early detection and treatment are the most important elements in reducing the incidence of melanoma deaths. Acquired melanocytic naevi (AMN) are well-known precursors of melanoma but most of our knowledge on the clinico-dermoscopic phenotypes of AMN...

["Dermatology"]
doi:10.7717/peerj.4168
2 citations
377 downloads
1,146 views

Background Skin microbiome varies from person to person due to a combination of various factors, including age, biogeography, sex, cosmetics and genetics. Many skin disorders appear to be related to the resident microflora, yet databases of facial skin microbiome...

["Microbiology","Dermatology"]
doi:10.7717/peerj.4084
1 citation
130 downloads
555 views

Aims Periodontitis and psoriatic disease, including psoriasis (PS) and psoriatic arthritis (PsA), share the common risk factors and co-morbidities. However, the risk of periodontitis in patients with psoriatic disease still needs further investigation. This study...

["Dentistry","Dermatology","Epidemiology","Public Health","Rheumatology"]
doi:10.7717/peerj.4064
153 downloads
719 views

A study was carried out to assess the effect of Stress Coat® on slime production in goldfish (Carassius auratus) and koi (Cyprinus carpio). The study also investigated histological changes that might be associated with slime producing cells, and wound healing in...

["Aquaculture, Fisheries and Fish Science","Veterinary Medicine","Zoology","Dermatology"]
doi:10.7717/peerj.3759
408 downloads
1,718 views

Identification of appropriate reference genes (RGs) is critical to accurate data interpretation in quantitative real-time PCR (qPCR) experiments. In this study, we have utilised next generation RNA sequencing (RNA-seq) to analyse the transcriptome of a panel of...

["Genomics","Molecular Biology","Dermatology","Oncology","Medical Genetics"]
doi:10.7717/peerj.3631
1 citation
367 downloads
737 views

Background Quercus infectoria G. Olivier (Fagaceae) nutgalls have been widely employed in traditional Asian medicine for several treatments, especially wounds and skin disorders. However, the effects of this plant on wound healing have not yet been clearly elucidated....

["Dermatology","Diabetes and Endocrinology","Evidence Based Medicine"]
doi:10.7717/peerj.3608
132 downloads
840 views

Background 2′–4′ Dinitrofluorobenzene (DNFB) induced contact hypersensitivity is an established model of contact sensitivity and leukocyte migration. Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) deficient mice were used to examine the role of PECAM-1...

["Cell Biology","Dermatology","Immunology"]
doi:10.7717/peerj.3555
121 downloads
610 views

Background There is currently no study that has evaluated the differences in epidemiological and clinical characteristics among rosacea patients according to different facial sites. Methods Clinical and demographic data were obtained from 586 rosacea patients....

["Dermatology","Epidemiology","Pharmacology"]
doi:10.7717/peerj.3527
7 citations
3,539 downloads
17,135 views

Importance Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers’ full prescribing information (FPI) for finasteride and dutasteride state that risk...

["Dermatology","Epidemiology","Internal Medicine","Pharmacology","Urology"]
doi:10.7717/peerj.3020
1 citation
324 downloads
1,310 views

It has previously been shown that domestic dogs and their household owners share bacterial populations, and that sharing of bacteria between humans is facilitated through the presence of dogs in the household. However, less is known regarding the bacterial communities...

["Microbiology","Veterinary Medicine","Dermatology"]
doi:10.7717/peerj.3075
3 citations
317 downloads
1,464 views

Localized genomic variability is crucial for the ongoing conflicts between infectious microbes and their hosts. An understanding of evolutionary and adaptive patterns associated with genomic variability will help guide development of vaccines and antimicrobial...

["Microbiology","Dermatology"]
doi:10.7717/peerj.2959

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