Peer-reviewed Articles - Medicine

62 downloads
258 views

Background Candida albicans is a commensal fungus that inhabits the oral mucosal surface and causes oral and systemic candidiasis. Oral candidiasis most commonly occurs in patients with AIDS, denture wearers and newborn children. Systemic candidiasis occurs mainly...

["Microbiology","Dentistry","Infectious Diseases","Women\u2019s Health"]
doi:10.7717/peerj.5685
70 downloads
215 views

Background The objective of this study was to characterize the oral microflora profile of primary Sjögren’s syndrome (pSS) patients, thereby revealing the connection between oral bacterial composition and dental caries, and to identify the “core microbiome” in...

["Microbiology","Molecular Biology","Allergy and Clinical Immunology","Dentistry"]
doi:10.7717/peerj.5649
71 downloads
673 views

Objectives The five-year survival rate of head and neck cancer (HNC) after radiotherapy (RT) varies widely from 35% to 89%. Many studies have addressed the effect of socioeconomic status and urban dwelling on the survival of HNC, but a limited number of studies...

["Dentistry","Oncology","Otorhinolaryngology","Public Health"]
doi:10.7717/peerj.5591
90 downloads
290 views

Background Contextual factors may influence oral health-related quality of life (OHRQoL) in children. The aim of the present study was to evaluate the influence of individual and contextual determinants of OHRQoL based on the perceptions of children. Methods A...

["Dentistry","Epidemiology"]
doi:10.7717/peerj.5451
58 downloads
274 views

Background Strains of periodontal disease-associated bacterium Porphyromonas gingivalis have different pathogenicity, which can be attributed to clonal genetic diversity. P. gingivalis typically expresses two types of fimbriae, FimA and Mfa1, which comprise six...

["Biochemistry","Microbiology","Dentistry"]
doi:10.7717/peerj.5581
169 downloads
2,058 views

Osteogenesis imperfecta (OI) is a genetic disorder that is usually caused by disturbed production of collagen type I. Depending on its severity in the patient, this disorder may create difficulties and challenges for the dental practitioner. The goal of this article...

["Genetics","Dentistry"]
doi:10.7717/peerj.5464
65 downloads
566 views

Background The purpose of this study was to investigate the relationship between chronic periodontitis (CP) and upper urinary tract stone (UUTS) in Taiwan by using a population-based data set. Methods A total of 16,292 CP patients and 48,876 randomly-selected controls...

["Dentistry","Epidemiology","Public Health","Urology"]
doi:10.7717/peerj.5287
112 downloads
1,025 views

Objectives To assess the prevalence and extent of chronic periodontitis, and its risk factors in a Portuguese subpopulation referred to periodontal examination. Methods This retrospective cross-sectional study used a subset of data from patients who sought dental...

["Dentistry","Epidemiology","Public Health"]
doi:10.7717/peerj.5258
147 downloads
417 views

Background Long noncoding RNAs (lncRNAs) are regulatory molecules that participate in biological processes such as stem cell differentiation. Periodontal ligament stem cells (PDLSCs) exhibit great potential for the regeneration of periodontal tissue and the formation...

["Bioinformatics","Dentistry","Infectious Diseases"]
doi:10.7717/peerj.5214
83 downloads
486 views

Many reports have mentioned the association between chronic periodontitis (CP) and primary Sjögren syndrome (pSS). However, no cohort study has been performed for the risk of pSS in patients with CP. In this study, we evaluated the risk of pSS from CP exposure...

["Dentistry","Epidemiology","Immunology","Public Health","Rheumatology"]
doi:10.7717/peerj.5109
174 downloads
524 views

Background Dental caries remains the most prevalent and costly oral infectious disease worldwide, encouraging the search for new and more effective antimicrobials. Therefore, the aim of this work was to study the antimicrobial action of selected phytochemicals...

["Microbiology","Dentistry"]
doi:10.7717/peerj.4872
113 downloads
767 views

Background Periodontitis is associated with increased concentration of inflammatory markers and saliva has been proposed as a non-invasive diagnostic fluid in oral and systemic diseases. The levels of salivary biomarkers, such as cytokines, could potentially be...

["Dentistry","Epidemiology","Immunology","Nursing"]
doi:10.7717/peerj.4710
116 downloads
560 views

Background The number of oropharyngeal lesions caused by HPV (Human papillomavirus) has been increasing worldwide in the past years. In spite of the clinical relevance of HPV infection in the anogenital tract of HIV-positive patients, the relevance of oropharynx...

["Dentistry","HIV","Immunology","Pathology"]
doi:10.7717/peerj.4407
1 citation
649 downloads
1,942 views

Background The interactions between the gut microbiome and obesity have been extensively studied. Although the oral cavity is the gateway to the gut, and is extensively colonized with microbes, little is known about the oral microbiome in people with obesity. In...

["Genomics","Microbiology","Dentistry"]
doi:10.7717/peerj.4458
2 citations
140 downloads
1,059 views

Digital photographs taken under controlled conditions were used to examine the incidence of linear enamel hypoplasia defects (LEHs) in burials from the Buckeye Knoll archaeological site (41VT98 Victoria county, Texas), which spans the Early to Late Archaic Period...

["Anthropology","Dentistry"]
doi:10.7717/peerj.4367

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