Peer-reviewed Articles - Medicine

29 downloads
106 views

Background Long noncoding RNAs (lncRNAs) are regulatory molecules that participate in biological processes such as stem cell differentiation. Periodontal ligament stem cells (PDLSCs) exhibit great potential for the regeneration of periodontal tissue and the formation...

["Bioinformatics","Dentistry","Infectious Diseases"]
doi:10.7717/peerj.5214
43 downloads
345 views

Many reports have mentioned the association between chronic periodontitis (CP) and primary Sjögren syndrome (pSS). However, no cohort study has been performed for the risk of pSS in patients with CP. In this study, we evaluated the risk of pSS from CP exposure...

["Dentistry","Epidemiology","Immunology","Public Health","Rheumatology"]
doi:10.7717/peerj.5109
71 downloads
341 views

Background Dental caries remains the most prevalent and costly oral infectious disease worldwide, encouraging the search for new and more effective antimicrobials. Therefore, the aim of this work was to study the antimicrobial action of selected phytochemicals...

["Microbiology","Dentistry"]
doi:10.7717/peerj.4872
83 downloads
585 views

Background Periodontitis is associated with increased concentration of inflammatory markers and saliva has been proposed as a non-invasive diagnostic fluid in oral and systemic diseases. The levels of salivary biomarkers, such as cytokines, could potentially be...

["Dentistry","Epidemiology","Immunology","Nursing"]
doi:10.7717/peerj.4710
82 downloads
436 views

Background The number of oropharyngeal lesions caused by HPV (Human papillomavirus) has been increasing worldwide in the past years. In spite of the clinical relevance of HPV infection in the anogenital tract of HIV-positive patients, the relevance of oropharynx...

["Dentistry","HIV","Immunology","Pathology"]
doi:10.7717/peerj.4407
1 citation
429 downloads
1,550 views

Background The interactions between the gut microbiome and obesity have been extensively studied. Although the oral cavity is the gateway to the gut, and is extensively colonized with microbes, little is known about the oral microbiome in people with obesity. In...

["Genomics","Microbiology","Dentistry"]
doi:10.7717/peerj.4458
109 downloads
882 views

Digital photographs taken under controlled conditions were used to examine the incidence of linear enamel hypoplasia defects (LEHs) in burials from the Buckeye Knoll archaeological site (41VT98 Victoria county, Texas), which spans the Early to Late Archaic Period...

["Anthropology","Dentistry"]
doi:10.7717/peerj.4367
183 downloads
697 views

Background Glycine air polishing has been proved to be safe, comfortable and time-saving. Whether it could substitute ultrasonic scaling to remove dental plaque biofilm during periodontal maintenance remains unclear. The purposes of this study were to evaluate...

["Microbiology","Clinical Trials","Dentistry","Drugs and Devices","Evidence Based Medicine"]
doi:10.7717/peerj.4371
92 downloads
553 views

Background Patients with chronic orofacial pain due to temporomandibular disorders (TMD) display alterations in somatosensory processing at the jaw, such as amplified perception of tactile stimuli, but the underlying mechanisms remain unclear. This study investigated...

["Dentistry","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.4310
563 downloads
2,218 views

Introduction Dental practitioners are exposed to different occupational hazards during the course of their professional activity, such as physical, chemical, biological, ergonomic factors. The ergonomic hazards, caused by strained posture and prolonged repetitive...

["Dentistry","Public Health"]
doi:10.7717/peerj.4154
164 downloads
825 views

Background Clear aligners are well known for facilitating oral hygiene maintenance and decreasing susceptibility to periodontal diseases as compared to conventional fixed appliances. However, few research studies focus on the subgingival microbial community during...

["Microbiology","Dentistry"]
doi:10.7717/peerj.4207
325 downloads
2,607 views

Previous investigations document functional and phylogenetic signals in the histology of dinosaur teeth. In particular, incremental lines in dentin have been used to determine tooth growth and replacement rates in several dinosaurian clades. However, to date, few...

["Paleontology","Anatomy and Physiology","Dentistry","Histology"]
doi:10.7717/peerj.4129
112 downloads
795 views

Previously, we revealed that several kampo medicines used for patients with excess and/or medium patterns (kakkonto (TJ-1), shosaikoto (TJ-9), hangeshashinto (TJ-14), and orento (TJ-120)) reduced prostaglandin (PG)E2 levels using LPS-treated human gingival fibroblasts...

["Cell Biology","Dentistry","Pharmacology"]
doi:10.7717/peerj.4120
2 citations
137 downloads
690 views

Aims Periodontitis and psoriatic disease, including psoriasis (PS) and psoriatic arthritis (PsA), share the common risk factors and co-morbidities. However, the risk of periodontitis in patients with psoriatic disease still needs further investigation. This study...

["Dentistry","Dermatology","Epidemiology","Public Health","Rheumatology"]
doi:10.7717/peerj.4064
140 downloads
815 views

Background The misunderstanding of specific vocabulary may hamper the patient-health provider communication. The 20-item Rapid Estimate Adult Literacy in Medicine and Dentistry (REALMD-20) was constructed to screen patients by their ability in reading medical/dental...

["Dentistry","Health Policy","Science and Medical Education"]
doi:10.7717/peerj.3744

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