Peer-reviewed Articles - Medicine

45 downloads
192 views

Background The use of an implantable cardioverter-defibrillator (ICD) has been established as an effective secondary prevention strategy for ventricular tachycardia (VT)/ventricular fibrillation (VF). However, few reports discuss the difference in clinical predictors...

["Cardiology"]
doi:10.7717/peerj.5312
60 downloads
179 views

Objective MicroRNA (miR)-122 is highly expressed in the liver, where it has been implicated as a regulator of fatty-acid metabolism. A recent study reported that miR-122 plays a role in pathogenesis of atherosclerosis; however, whether it connects with severity...

["Cardiology","Geriatrics"]
doi:10.7717/peerj.5218
61 downloads
225 views

Introduction Chronic total occlusion (CTO) is common in the presence of other significantly narrowed coronary arteries. The impact of total occlusion and its association with completeness of revascularization on patients with multivessel disease undergoing coronary...

["Cardiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4909
56 downloads
358 views

Background Minimally invasive mitral valve surgery (MVS) via right mini-thoracotomy has recently attracted a lot of attention. Minimally invasive MVS shows postoperative results that are comparable to those of conventional MVS through the median sternotomy as per...

["Cardiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4810
80 downloads
397 views

Occlusive artery disease (CAD) is the leading cause of death worldwide. Bypass graft surgery remains the most prevalently performed treatment for occlusive arterial disease, and veins are the most frequently used conduits for surgical revascularization. However,...

["Bioinformatics","Cell Biology","Genetics","Genomics","Cardiology"]
doi:10.7717/peerj.4704
109 downloads
456 views

Background Good results of drug-eluting balloon (DEB) use are achieved in in-stent restenosis (ISR) lesions, small vessel disease, long lesions, and bifurcations. However, few reports exist about DEB use in acute myocardial infarction (AMI) with ISR. This study’s...

["Cardiology"]
doi:10.7717/peerj.4646
113 downloads
670 views

Background Kawasaki disease (KD) is an immune-mediated systemic vasculitis, and infection plays an important role in the pathophysiology of KD. The susceptibility to infectious disease in patients with KD remains largely unclear. This study aimed to investigate...

["Allergy and Clinical Immunology","Cardiology","Immunology","Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.4539
152 downloads
832 views

Background Patients with acute myocardial infarction (AMI) and bundle-branch block have poor prognoses. The new European Society of Cardiology guideline suggests a primary percutaneous coronary intervention strategy when persistent ischemic symptoms occur in patients...

["Cardiology"]
doi:10.7717/peerj.4497
164 downloads
1,486 views

RNA editing modifies transcripts and may alter their regulation or function. In humans, the most common modification is adenosine to inosine (A-to-I). We examined the global characteristics of RNA editing in 4,301 human tissue samples. More than 1.6 million A-to-I...

["Computational Biology","Genetics","Genomics","Cardiology","Computational Science"]
doi:10.7717/peerj.4466
126 downloads
1,019 views

Objectives To assess and compare the predictive ability of three risk evaluation systems (SinoSCORE, EuroSCORE II and the STS risk evaluation system) in patients aged ≥70, and who underwent coronary artery bypass grafting (CABG) in East China. Methods Three risk...

["Cardiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4413
188 downloads
972 views

Background Although several studies have identified risk factors for high blood pressure (BP), data from Afro-Caribbean populations are limited. Additionally, less is known about how putative risk factors operate in young adults and how social factors influence...

["Cardiology","Epidemiology","Global Health","Internal Medicine","Public Health"]
doi:10.7717/peerj.4385
292 downloads
1,204 views

Objectives We aimed to evaluate the global scientific output of gene research of myocardial infarction and explore their hotspots and frontiers from 2001 to 2015, using bibliometric methods. Methods Articles about the gene research of myocardial infarction between...

["Genetics","Cardiology","Statistics","Medical Genetics"]
doi:10.7717/peerj.4354
1 citation
134 downloads
1,029 views

There is growing interest in applying detailed mathematical models of the heart for ion-channel related cardiac toxicity prediction. However, a debate as to whether such complex models are required exists. Here an assessment in the predictive performance between...

["Mathematical Biology","Toxicology","Cardiology","Pharmacology"]
doi:10.7717/peerj.4352
127 downloads
967 views

Background Long non-coding RNAs (lncRNAs) have been reported to modulate cardiovascular diseases, and expression dynamics of lncRNAs in the bloodstream were proposed to be potential biomarkers for clinical diagnosis. However, few cardiovascular diseases-related...

["Molecular Biology","Cardiology","Pathology","Public Health"]
doi:10.7717/peerj.4246
1 citation
170 downloads
695 views

Background Bedside non-invasive techniques, such as radial artery tonometry, to estimate hemodynamic parameters have gained increased relevance as an attractive alternative and efficient method to measure hemodynamics in outpatient departments. For our pilot study,...

["Cardiology","Drugs and Devices"]
doi:10.7717/peerj.4132

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