Peer-reviewed Articles - Medicine

74 downloads
318 views

Background Obesity is a possible factor which affects severity of symptoms and disease activity in fibromyalgia syndrome (FMS). The aim of our study was to determine the association between body mass index (BMI) and pain, tender point count (TPC), disease activity,...

["Anesthesiology and Pain Management","Public Health","Rheumatology"]
doi:10.7717/peerj.4917
77 downloads
191 views

Estimating the depth of anaesthesia (DoA) in operations has always been a challenging issue due to the underlying complexity of the brain mechanisms. Electroencephalogram (EEG) signals are undoubtedly the most widely used signals for measuring DoA. In this paper,...

["Anesthesiology and Pain Management","Statistics","Computational Science"]
doi:10.7717/peerj.4817
59 downloads
344 views

Objectives Osteoarthritis (OA) and vitamin D deficiency are common health conditions in older people. Whether vitamin D concentration is associated with knee OA is controversial. In this study, we aimed to determine the association between serum concentrations...

["Anesthesiology and Pain Management","Orthopedics","Metabolic Sciences"]
doi:10.7717/peerj.4670
132 downloads
744 views

Background The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life. Here we aim to examine the expression profiles of transient...

["Molecular Biology","Neuroscience","Anesthesiology and Pain Management","Oncology","Pharmacology"]
doi:10.7717/peerj.4622
112 downloads
616 views

Background Patellofemoral pain (PFP) is often reported as a diffuse pain at the front of the knee during knee-loading activities. A patient’s description of pain location and distribution is commonly drawn on paper by clinicians, which is difficult to quantify,...

["Anesthesiology and Pain Management","Anatomy and Physiology","Orthopedics","Translational Medicine","Human\u2013Computer Interaction"]
doi:10.7717/peerj.4406
2 citations
100 downloads
514 views

Evaluation of depth of anaesthesia (DoA) is critical in clinical surgery. Indices derived from electroencephalogram (EEG) are currently widely used to quantify DoA. However, there are known to be inaccurate under certain conditions; therefore, experienced anaesthesiologists...

["Anesthesiology and Pain Management","Computational Science","Statistics"]
doi:10.7717/peerj.4067
145 downloads
676 views

The role of glial cells in pain modulation has recently gathered attention. The objective of this study was to determine healthy spinal microglia and astrocyte morphology and disposition in equine spinal cord dorsal horns using Iba-1 and GFAP/Cx-43 immunofluorescence...

["Anesthesiology and Pain Management","Molecular Biology","Neuroscience","Veterinary Medicine"]
doi:10.7717/peerj.3965
3 citations
143 downloads
665 views

Background Respondent fatigue, also known as survey fatigue, is a common problem in the collection of survey data. Factors that are known to influence respondent fatigue include survey length, survey topic, question complexity, and open-ended question type. There...

["Anesthesiology and Pain Management","Global Health","Human-Computer Interaction","Statistics"]
doi:10.7717/peerj.3785
1 citation
293 downloads
1,165 views

Background New-onset atrial fibrillation (AF) is the most common arrhythmia in critically ill patients. Although evidence base and expert consensus opinion for management have been summarised in several international guidelines, no specific considerations for critically...

["Anesthesiology and Pain Management","Cardiology","Emergency and Critical Care"]
doi:10.7717/peerj.3716
1 citation
83 downloads
468 views

Background Because etomidate induces prolonged adrenal suppression, even following a single bolus, its use as an infused anesthetic is limited. Our previous study indicated that a single administration of the novel etomidate analog methoxyethyletomidate hydrochloride...

["Anesthesiology and Pain Management","Animal Behavior","Neuroscience","Veterinary Medicine"]
doi:10.7717/peerj.3693
128 downloads
586 views

Background Hypoxia-inducible factor (HIF)-1 is involved in the regulation of hypoxic preconditioning in cardiomyocytes. Under hypoxic conditions, HIF-1α accumulates and is translocated to the nucleus, where it forms an active complex with HIF-1β and activates transcription...

["Anesthesiology and Pain Management","Cardiology","Cell Biology"]
doi:10.7717/peerj.3662
290 downloads
1,648 views

Background Previous studies in human patients suggest depth of sedation may be affected by environmental noise or music; however, related data in domestic animals is limited. The objective of the current study was to investigate the effect of noise and music on...

["Anesthesiology and Pain Management","Animal Behavior","Veterinary Medicine"]
doi:10.7717/peerj.3659
1 citation
172 downloads
664 views

Background Deliberate hypotension is one way to achieve a bloodless surgical field in endoscopic sinus surgery (ESS). We compared two anaesthesia regimens to induce deliberate hypotension and attempted to determine the most efficient one. Methods Fifty-nine patients...

["Anesthesiology and Pain Management","Clinical Trials","Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3370
6 citations
238 downloads
758 views

Background Sevoflurane postconditioning (S-post) has similar cardioprotective effects as ischemic preconditioning. However, the underlying mechanism of S-post has not been fully elucidated. Janus kinase signaling transduction/transcription activator (JAK2–STAT3)...

["Anesthesiology and Pain Management","Cardiology","Translational Medicine"]
doi:10.7717/peerj.3196
2 citations
429 downloads
1,424 views

Background The ergogenic effects of analgesic substances suggest that pain perception is an important regulator of work-rate during fatiguing exercise. Recent research has shown that endogenous inhibitory responses, which act to attenuate nociceptive input and...

["Anesthesiology and Pain Management","Neurology","Neuroscience","Psychiatry and Psychology"]
doi:10.7717/peerj.3028

Refine by manuscript type

Top subject areas - Articles

Top subject areas - People

View all subject areas