Peer-reviewed Articles - Medicine

27 downloads
205 views

Background Severe equine asthma is a chronic inflammatory disease of the lung in horses similar to low-Th2 late-onset asthma in humans. This study aimed to determine the utility of RNA-Seq to call gene sequence variants, and to identify sequence variants of potential...

["Genetics","Veterinary Medicine","Allergy and Clinical Immunology","Respiratory Medicine"]
doi:10.7717/peerj.5759
57 downloads
185 views

Background The objective of this study was to characterize the oral microflora profile of primary Sjögren’s syndrome (pSS) patients, thereby revealing the connection between oral bacterial composition and dental caries, and to identify the “core microbiome” in...

["Microbiology","Molecular Biology","Allergy and Clinical Immunology","Dentistry"]
doi:10.7717/peerj.5649
64 downloads
339 views

Background Nut consumption at the population level remains low despite the well-documented benefits of their consumption, including their cardioprotective effects. Studies have suggested that advice from health professionals may be a means to increase nut consumption...

["Allergy and Clinical Immunology","Nutrition","Public Health"]
doi:10.7717/peerj.5500
64 downloads
339 views

Background Pemphigus is a common life-threatening, autoimmune bullous disease effecting both cutaneous and mucous membranes. Previous diagnosis of pemphigus is based on clinical presentations, histopathology, immunofluorescence and enzyme-linked immunosorbent assay....

["Allergy and Clinical Immunology","Dermatology","Immunology"]
doi:10.7717/peerj.5388
123 downloads
728 views

Background Kawasaki disease (KD) is an immune-mediated systemic vasculitis, and infection plays an important role in the pathophysiology of KD. The susceptibility to infectious disease in patients with KD remains largely unclear. This study aimed to investigate...

["Allergy and Clinical Immunology","Cardiology","Immunology","Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.4539
202 downloads
1,126 views

This study assessed in detail the influence of four different human proteins on the activation of CD4+ and CD8+ T lymphocytes and on the formation of regulatory T cells. Human whole-blood samples were incubated with four different human proteins. The effects of...

["Allergy and Clinical Immunology","Immunology","Internal Medicine","Pathology","Pediatrics"]
doi:10.7717/peerj.4462
498 downloads
935 views

Background Beaches are recreational spots for people. However, beach sand contains harmful microbes that affect human health, and there are no established methods for either sampling and identifying beach-borne pathogens or managing the quality of beach sand. Method...

["Biotechnology","Marine Biology","Allergy and Clinical Immunology","Pathology","Public Health"]
doi:10.7717/peerj.4245
1 citation
194 downloads
1,524 views

Energy buffering systems are key for homeostasis during variations in energy supply. Spiders are the most important predators for insects and therefore key in terrestrial ecosystems. From biomedical interest, spiders are important for their venoms and as a source...

["Biochemistry","Biophysics","Zoology","Allergy and Clinical Immunology"]
doi:10.7717/peerj.3787
4 citations
170 downloads
1,100 views

Background Oxytetracycline (OTC), which is largely employed in zootechnical and veterinary practices to ensure wellness of farmed animals, is partially absorbed within the gastrointestinal tract depositing in several tissues. Therefore, the potential OTC toxicity...

["Cell Biology","Allergy and Clinical Immunology","Drugs and Devices","Immunology","Pharmacology"]
doi:10.7717/peerj.3236
2 citations
215 downloads
1,042 views

This study investigated the mechanism of protein disulfide-isomerase A3 (PDIA3)-induced visceral hypersensitivity in irritable bowel syndrome (IBS). Rats were treated with saline (control), acetic acid and restraint stress (IBS model), empty vector (RNAi control)...

["Allergy and Clinical Immunology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.2644
3 citations
459 downloads
991 views

Introduction Rituximab (RTX) is a B cell-depleting agent approved for the treatment of granulomatosis with polyangiitis (GPA). RTX reduces antibody producing precursor plasma cells and inhibits B and T cells interaction. Infections related to T cell immunodeficiency...

["Allergy and Clinical Immunology","Internal Medicine","Rheumatology"]
doi:10.7717/peerj.2487
4 citations
254 downloads
1,126 views

Background. CD8+ T lymphocytes are known to play a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, systematic analyses of CD8+ T cell (Cytotoxic T cells, Tc) subsets in COPD patients have yet to be well conducted. Methods....

["Allergy and Clinical Immunology","Immunology","Respiratory Medicine"]
doi:10.7717/peerj.2301
6 citations
601 downloads
2,072 views

Background. Resveratrol is a natural polyphenol that exhibits anti-inflammatory effects. The aim of this study was to investigate the effects of resveratrol treatment on epithelium-derived cytokines and epithelial apoptosis in a murine model of atopic dermatitis-like...

["Allergy and Clinical Immunology","Dermatology","Immunology"]
doi:10.7717/peerj.1889
342 downloads
1,412 views

Background. Previous studies have shown that psychological stress is linked to asthma prevalence. Parental psychological stress may potentially influence inflammatory responses in their allergic children. The purpose of this study is to clarify the association...

["Allergy and Clinical Immunology","Epidemiology","Nursing","Pediatrics","Psychiatry and Psychology"]
doi:10.7717/peerj.1585
2 citations
247 downloads
1,493 views

Objective. Chronic nasal carriage of Staphylococcus aureus (SA) increases the risk of relapse while Rituximab (RTX) is an effective agent for inducing and maintaining remission in patients with Granulomatosis with polyangiitis (GPA). We investigated whether B cell...

["Allergy and Clinical Immunology","Immunology","Infectious Diseases","Internal Medicine","Rheumatology"]
doi:10.7717/peerj.1051

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