Peer-reviewed Articles - Biology

Orf, caused by Orf virus (ORFV), is a globally distributed zoonotic disease responsible for serious economic losses in the agricultural sector. However, the mechanism underlying ORFV infection remains largely unknown. Circular RNAs (circRNAs), a novel type of endogenous...

["Bioinformatics","Molecular Biology","Virology"]
doi:10.7717/peerj.6267
40 downloads
143 views

Purpose The most common virus vector used in gene therapy research for ophthalmologic diseases is the adeno-associated virus (AAV) vector, which has been used successfully in a number of preclinical and clinical studies. It is important to evaluate novel AAV vectors...

["Virology","Ophthalmology"]
doi:10.7717/peerj.6317
33 downloads
111 views

Plant vegetative propagation strategies for agricultural crops cause the accumulation of viruses, resulting in the formation of virus complexes or communities. The cultivation of garlic is based on vegetative propagation and more than 13 virus species from the...

["Agricultural Science","Microbiology","Virology"]
doi:10.7717/peerj.6285
49 downloads
153 views

Background The emergence of multidrug- or extensively drug-resistant Acinetobacter baumannii has made it difficult to treat and control infections caused by this bacterium. It is urgently necessary to search for alternatives to conventional antibiotics for control...

["Microbiology","Molecular Biology","Virology"]
doi:10.7717/peerj.6173
78 downloads
520 views

Wild plant populations may harbour a myriad of unknown viruses. As the majority of research efforts have targeted economically important plant species, the diversity and prevalence of viruses in the wild has remained largely unknown. However, the recent shift towards...

["Bioinformatics","Ecology","Plant Science","Virology","Population Biology"]
doi:10.7717/peerj.6140
31 downloads
190 views

Identifying cis-acting elements and understanding regulatory mechanisms of a gene is crucial to fully understand the molecular biology of an organism. In general, it is difficult to identify previously uncharacterised cis-acting elements with an unknown consensus...

["Bioinformatics","Evolutionary Studies","Genetics","Virology","Data Science"]
doi:10.7717/peerj.6176
26 downloads
118 views

Background Hemorrhagic fever with renal syndrome is in most cases caused by the Hantaan virus (HTNV) and Seoul virus (SEOV). To develop and apply reverse transcription loop-mediated isothermal amplification (RT-LAMP) to detect HTNV and SEOV simultaneously, which...

["Microbiology","Molecular Biology","Veterinary Medicine","Virology"]
doi:10.7717/peerj.6068
81 downloads
544 views

In addition to encoding RNA primary structures, genomes also encode RNA secondary and tertiary structures that play roles in gene regulation and, in the case of RNA viruses, genome replication. Methods for the identification of functional RNA structures in genomes...

["Bioinformatics","Molecular Biology","Virology"]
doi:10.7717/peerj.6136
67 downloads
199 views

Background A virus-like particle (VLP) is an excellent tool for a compound delivery system due to its simple composition, symmetrical structure and self-assembly. Its surface modification both chemically and genetically is established, leading to the target-specific...

["Aquaculture, Fisheries and Fish Science","Biotechnology","Cell Biology","Molecular Biology","Virology"]
doi:10.7717/peerj.6079
76 downloads
466 views

Ranaviruses can infect many vertebrate classes including fish, amphibians and reptiles, but for the most part, research has been focused on non-reptilian hosts, amphibians in particular. More recently, reports of ranaviral infections of reptiles are increasing...

["Veterinary Medicine","Virology"]
doi:10.7717/peerj.6083
60 downloads
279 views

Next-Generation Sequencing (NGS) technologies provide unique possibilities for the comprehensive assessment of the environmental diversity of bacteriophages. Several Bacillus bacteriophages have been isolated, but very few Bacillus megaterium bacteriophages have...

["Agricultural Science","Bioinformatics","Genomics","Virology"]
doi:10.7717/peerj.5687
53 downloads
227 views

Background Enterocytozoon hepatopenaei (EHP) is a newly emerged microsporidian parasite that causes retarded shrimp growth in many countries. But there are no effective approaches to control this disease to date. The EHP could be an immune risk factor for increased...

["Veterinary Medicine","Virology","Infectious Diseases"]
doi:10.7717/peerj.5993
131 downloads
683 views

Predicting and simplifying which pathogens may spill over from animals to humans is a major priority in infectious disease biology. Many efforts to determine which viruses are at risk of spillover use a subset of viral traits to find trait-based associations with...

["Evolutionary Studies","Virology","Infectious Diseases","Statistics"]
doi:10.7717/peerj.5979
1 citation
69 downloads
439 views

Protection of honey bees is of great economic importance because of their role in pollination. Crucial steps towards this goal are epidemiological surveys of pathogens connected with honey bee losses. In this study deformed wing virus (DWV), chronic bee paralysis...

["Biodiversity","Entomology","Veterinary Medicine","Virology"]
doi:10.7717/peerj.5887
63 downloads
237 views

The hepatitis C virus RNA genome possesses a variety of conserved structural elements, in both coding and non-coding regions, that are important for viral replication. These elements are known or predicted to modulate key life cycle events, such as translation...

["Microbiology","Molecular Biology","Virology"]
doi:10.7717/peerj.5870

Refine by manuscript type

Top subject areas - Articles

Top subject areas - People

View all subject areas