Peer-reviewed Articles - Biology

52 downloads
280 views

Background Following active muscle lengthening, there is an increase in steady-state isometric force as compared with a purely isometric contraction at the same muscle length and level of activation. This fundamental property of skeletal muscle is known as residual...

["Neuroscience","Kinesiology"]
doi:10.7717/peerj.5421
33 downloads
236 views

Avoidance is a common feature of post-traumatic stress disorder (PTSD) as well as anxiety and depressive disorders. Avoidance can be expressed behaviorally as well as cognitively. Most personality assessments for avoidance involve self-report inventories which...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7717/peerj.5330
44 downloads
376 views

Studies have suggested that oxidative stress may contribute to the pathogenesis of mental disorders. In this context, molecules with antioxidant activity may be promising agents in the treatment of these deleterious conditions. Acetyl-L-carnitine (ALC) is a multi-target...

["Neuroscience","Pharmacology"]
doi:10.7717/peerj.5309
42 downloads
370 views

Previous works have shown that neurons from the ventral premotor cortex (PMv) represent several elements of perceptual decisions. One of the most striking findings was that, after the outcome of the choice is known, neurons from PMv encode all the information necessary...

["Neuroscience"]
doi:10.7717/peerj.5395
39 downloads
360 views

Cortical morphology is known to differ with age, as measured by cortical thickness, fractal dimensionality, and gyrification. However, head motion during MRI scanning has been shown to influence estimates of cortical thickness as well as increase with age. Studies...

["Neuroscience","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.5176
73 downloads
649 views

Background Emotion identification is a fundamental component of social cognition. Although it is well established that a general cognitive decline occurs with advancing age, the effects of age on emotion identification is still unclear. A meta-analysis by Ruffman...

["Developmental Biology","Neuroscience","Psychiatry and Psychology"]
doi:10.7717/peerj.5278
45 downloads
347 views

Background Criminal defendants may often exaggerate psychiatric symptoms either to appear non-accountable for their actions or to mitigate their imprisonment. Several psychometric tests have been proposed to detect malingering. These instruments are often validated...

["Neuroscience","Psychiatry and Psychology","Legal Issues"]
doi:10.7717/peerj.5259
65 downloads
289 views

Introduction Sleep scoring is an important step in the treatment of sleep disorders. Manual annotation of sleep stages is time-consuming and experience-relevant and, therefore, needs to be done using machine learning techniques. Methods Sleep-EDF polysomnography...

["Bioinformatics","Neuroscience","Data Mining and Machine Learning"]
doi:10.7717/peerj.5247
82 downloads
1,269 views

Environmental enrichment is widely used to improve welfare and behavioral performance of animal species. It ensures housing of laboratory animals in environments with space and complexity that enable the expression of their normal behavioral repertoire. Auditory...

["Neuroscience","Freshwater Biology"]
doi:10.7717/peerj.5162
71 downloads
276 views

Background Stargardt disease (SD) is characterized by the accumulation of the age-pigment lipofuscin in the retinal pigment epithelium (RPE) and subsequent neuroretinal degeneration. The disease leads to vision loss early in life. Here, we investigate age-dependent...

["Cell Biology","Neuroscience","Ophthalmology","Pathology","Histology"]
doi:10.7717/peerj.5215
649 downloads
7,531 views

Background Experimental and clinical evidence support a link between body representations and pain. This proof-of-concept study in people with painful knee osteoarthritis (OA) aimed to determine if: (i) visuotactile illusions that manipulate perceived knee size...

["Neuroscience","Anesthesiology and Pain Management","Orthopedics","Psychiatry and Psychology","Rheumatology"]
doi:10.7717/peerj.5206
70 downloads
307 views

In the field of comparative neuroanatomy, a meaningful interspecific comparison demands quantitative data referring to method-specific artifacts. For evaluating the potential of state-of-the-art imaging techniques in arthropod neuroanatomy, micro-computed X-ray...

["Neuroscience","Zoology"]
doi:10.7717/peerj.5181
46 downloads
389 views

Introduction The determination of fatigue and exhaustion in experimental animals is complicated by the subjective nature of the measurement. Typically, it requires an observer to watch exercising animals, e.g. rats running on the treadmill, and to identify the...

["Animal Behavior","Neuroscience","Anatomy and Physiology"]
doi:10.7717/peerj.5017
130 downloads
939 views

Background The enriched environment (EE) is a laboratory housing model that emerged from efforts to minimize the impact of environmental conditions on laboratory animals. Recently, we showed that EE promoted positive effects on behavior and cortisol levels in zebrafish...

["Neuroscience","Zoology"]
doi:10.7717/peerj.5136
62 downloads
368 views

Objective Cannabis, like other substances, negatively affects health, inducing respiratory problems and mental and cognitive alterations. Memory and learning disorders, as well as executive dysfunctions, are also neuropsychological disorders associated to cannabis...

["Neuroscience","Cognitive Disorders","Public Health"]
doi:10.7717/peerj.5201

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