Peer-reviewed Articles - Biology

18 downloads
134 views

The archaellum, the rotating motility structure of archaea, is best studied in the crenarchaeon Sulfolobus acidocaldarius. To better understand how assembly and rotation of this structure is driven, two ATP-binding proteins, FlaI and FlaH of the motor complex of...

["Biochemistry","Microbiology","Molecular Biology"]
doi:10.7717/peerj.4984
45 downloads
257 views

Every cell in an individual has largely the same genomic sequence and yet cells in different tissues can present widely different phenotypes. This variation arises because each cell expresses a specific subset of genomic instructions. Control over which instructions,...

["Biochemistry","Genetics","Molecular Biology","Metabolic Sciences"]
doi:10.7717/peerj.5062
31 downloads
243 views

Chemokine (C-C motif) ligand 7 (CCL7), a CC chemokine, is a chemotactic factor and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is widely expressed in multiple cell types and can participate in anti-inflammatory responses...

["Biochemistry","Cell Biology","Molecular Biology","Oncology"]
doi:10.7717/peerj.4928
61 downloads
210 views

Two forms of the monstrilloid copepod, one represented by males, the other by females, were dominant among the monstrilloids collected while sampling zooplankton with a light trap in southern coastal waters of Korea. Morphological examination revealed that the...

["Molecular Biology","Taxonomy","Zoology"]
doi:10.7717/peerj.4938
28 downloads
233 views

Apis cerana cerana relies on its sensitive olfactory system to perform foraging activities in the surrounding environment. Olfactory receptors (ORs) are a primary requirement for odorant recognition and coding. However, the molecular recognition of volatile compounds...

["Agricultural Science","Cell Biology","Entomology","Molecular Biology"]
doi:10.7717/peerj.5005
39 downloads
272 views

Background Electrical stimulation (ES) has a long history of successful use in the clinical treatment of refractory, non-healing bone fractures and has recently been proposed as an adjunct to bone tissue-engineering treatments to optimize their therapeutic potential....

["Cell Biology","Molecular Biology","Orthopedics"]
doi:10.7717/peerj.4959
41 downloads
216 views

Background Pyruvate kinase (PK) is responsible for the final reaction in glycolysis. As PK is a glycolytic control point, the analysis of PK posttranslational modifications (PTM) and kinetic changes reveals a key piece of the reorganization of energy metabolism...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.4918
30 downloads
250 views

Background Animal mitochondrial genomes typically encode 37 genes: 13 proteins, 22 tRNAs and two rRNAs. However, many species represent exceptions to that rule. Bivalvia along with Nematoda and Platyhelminthes are often suspected to fully or partially lack the...

["Genetics","Marine Biology","Molecular Biology"]
doi:10.7717/peerj.4897
45 downloads
298 views

Introduction of point mutations to a gene of interest is a powerful tool when determining protein function. CRISPR-mediated genome editing allows for more efficient transfer of a desired mutation into a wide range of model organisms. Traditionally, PCR amplification...

["Cell Biology","Genetics","Microbiology","Molecular Biology"]
doi:10.7717/peerj.4920
39 downloads
205 views

In this study, the mitochondrial genomes (mitogenomes) of two walnut leaf insect pests, Gastrolina depressa depressa and G. depressa thoracica, were sequenced by Sanger sequencing technology. The mitogenome of G. depressa thoracica was complete at 16,109 bp in...

["Entomology","Genomics","Molecular Biology","Taxonomy"]
doi:10.7717/peerj.4919
32 downloads
241 views

Background Hepatocellular carcinoma (HCC) is the most common and aggressive type of malignant liver tumor. HCC progression depends significantly on its vascularization and formation of new blood vessels. Vascular endothelial growth factor A (VEGFA) is a crucial...

["Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.4915
36 downloads
243 views

In Western countries dogs and cats are the most popular pets, and people are increasingly opposed to their rearing for the fur industry. In 2007, a Regulation of the European Union (EU) banned the use and trade of dog and cat furs, but an official analytical protocol...

["Biodiversity","Genetics","Molecular Biology","Veterinary Medicine","Legal Issues"]
doi:10.7717/peerj.4902
45 downloads
238 views

Background Inflammation is generally suppressed during hibernation, but select tissues (e.g. lung) have been shown to activate both antioxidant and pro-inflammatory pathways, particularly during arousal from torpor when breathing rates increase and oxidative metabolism...

["Animal Behavior","Molecular Biology"]
doi:10.7717/peerj.4911
47 downloads
230 views

Objective Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we determined the effect...

["Cell Biology","Molecular Biology","Rheumatology"]
doi:10.7717/peerj.4771
60 downloads
335 views

Microbial community structures of harmful algal bloom (HAB) caused by Heterosigma akashiwo in Geoje were analyzed using the MiSeq platform. To analyze phytoplankton communities without cross-reactivity with predominant bacteria, a new phytoplankton-specific 23S...

["Ecology","Genomics","Marine Biology","Molecular Biology"]
doi:10.7717/peerj.4854

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