Peer-reviewed Articles - Biology

96 downloads
618 views

The patterns of bone modeling and mineral mobilization (skeletal homeostasis) among mammals other than humans and laboratory rodents are still poorly known. In this study we assessed the pattern of bone formation and bone resorption in the femur of a wild population...

["Developmental Biology","Evolutionary Studies","Zoology","Anatomy and Physiology","Histology"]
doi:10.7717/peerj.4944
365 downloads
2,035 views

Background Plesiosaurs are marine reptiles that arose in the Late Triassic and survived to the Late Cretaceous. They have a unique and uniform bauplan and are known for their very long neck and hydrofoil-like flippers. Plesiosaurs are among the most successful...

["Evolutionary Studies","Paleontology","Statistics","Histology"]
doi:10.7717/peerj.4955
33 downloads
192 views

Conventional aquaculture feed materials available in Australia are expensive, which has prompted the search for alternatives that would be cost-effective and locally available. The present study was undertaken in order to maximize the use of a tuna hydrolysate...

["Aquaculture, Fisheries and Fish Science","Biochemistry","Histology"]
doi:10.7717/peerj.4870
55 downloads
300 views

Sorting nexin-1 (SNX1) is an important functional protein in cell endocytosis, efflux, protein sorting, cell signal transduction, etc; however, the expression, the role and clinical relevance of SNX1 have not been investigated in gastric cancer (GC). In this study,...

["Gastroenterology and Hepatology","Oncology","Histology"]
doi:10.7717/peerj.4829
62 downloads
331 views

Background Type 2 diabetes is characterized by insulin resistance accompanied by defective insulin secretion. Transgenic mouse models play an important role in medical research. However, single transgenic mouse models may not mimic the complex phenotypes of most...

["Agricultural Science","Biotechnology","Diabetes and Endocrinology","Histology","Medical Genetics"]
doi:10.7717/peerj.4542
1,145 downloads
2,029 views

Here we provide a detailed description of the postcranial skeleton of the holotype and referred specimens of Buitreraptor gonzalezorum. This taxon was recovered as an unenlagiine dromaeosaurid in several recent phylogenetic studies and is the best represented Gondwanan...

["Paleontology","Taxonomy","Histology"]
doi:10.7717/peerj.4558
88 downloads
733 views

Objective In the foveola of the eye, photoreceptors and Müller cells with a unique morphology have been described, but little is known about their 3D structure and orientation. Considering that there is an angle-dependent change in the foveolar photoreceptor response...

["Biophysics","Cell Biology","Anatomy and Physiology","Ophthalmology","Histology"]
doi:10.7717/peerj.4482
450 downloads
1,842 views

Finite Element Analysis (FEA) is a useful method for understanding form and function. However, modelling of fossil taxa invariably involves assumptions as a result of preservation-induced loss of information in the fossil record. To test the validity of predictions...

["Bioengineering","Paleontology","Histology"]
doi:10.7717/peerj.4426
144 downloads
696 views

Triple negative breast cancer (TNBC) is a belligerent carcinoma that is unresponsive to targeted receptor therapies. Development of new treatment strategies would benefit from an expanded repertoire of in vitro cell culture systems, such as those that support tridimensional...

["Cell Biology","Anatomy and Physiology","Oncology","Pathology","Histology"]
doi:10.7717/peerj.4340
312 downloads
2,464 views

Previous investigations document functional and phylogenetic signals in the histology of dinosaur teeth. In particular, incremental lines in dentin have been used to determine tooth growth and replacement rates in several dinosaurian clades. However, to date, few...

["Paleontology","Anatomy and Physiology","Dentistry","Histology"]
doi:10.7717/peerj.4129
156 downloads
997 views

Background Health of mammary glands is fundamental for milk and dairy products hygiene and quality, with huge impacts on consumers welfare. Methods This study aims to investigate the microbial agents (bacteria, fungi and lentiviruses) isolated from 89 macroscopically...

["Microbiology","Veterinary Medicine","Histology"]
doi:10.7717/peerj.3994
1 citation
277 downloads
746 views

Background Biomineralization, e.g., in sea urchins or mollusks, includes the assembly of mesoscopic superstructures from inorganic crystalline components and biopolymers. The resulting mesocrystals inspire biophysicists and material scientists alike, because of...

["Aquaculture, Fisheries and Fish Science","Cell Biology","Marine Biology","Zoology","Histology"]
doi:10.7717/peerj.3923
151 downloads
534 views

Insecticidal crystal (Cry) proteins produced by the bacterium Bacillus thuringiensis (Bt) target cells in the midgut epithelium of susceptible larvae. While the mode of action of Cry toxins has been extensively investigated, the midgut response to Cry intoxication...

["Entomology","Microbiology","Histology"]
doi:10.7717/peerj.3886
2 citations
651 downloads
1,885 views

Segmentation of histopathology sections is a necessary preprocessing step for digital pathology. Due to the large variability of biological tissue, machine learning techniques have shown superior performance over conventional image processing methods. Here we present...

["Bioengineering","Oncology","Radiology and Medical Imaging","Histology","Computational Science"]
doi:10.7717/peerj.3874
4 citations
205 downloads
946 views

Background Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, proliferation...

["Cell Biology","Oncology","Histology"]
doi:10.7717/peerj.3754

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