Peer-reviewed Articles - Biology

51 downloads
265 views

Background The mechanisms underlying human germ cell development and infertility remain largely unknown due to bioethical issues and the shortage of experimental materials. Therefore, an effective in vitro induction system of human primordial germ-like cells (hPGCLCs)...

["Cell Biology","Developmental Biology","Molecular Biology"]
doi:10.7717/peerj.6143
44 downloads
343 views

Background Histone deacetylases (HDACs) are epigenetic factors that function to repress gene transcription by removing acetyl groups from the N-terminal of histone lysines. Histone deacetylase 4 (HDAC4), a class IIa HDAC, has previously been shown to regulate the...

["Developmental Biology","Molecular Biology"]
doi:10.7717/peerj.6167
49 downloads
175 views

Inhibition of both MEK1/2 and glycogen synthase kinase-3 (GSK3; 2i system) facilitates the maintenance of naïve stemness for embryonic stem cells in various mammalian species. However, the effect of the inhibition of the 2i system on porcine early embryogenesis...

["Cell Biology","Developmental Biology","Zoology"]
doi:10.7717/peerj.5840
52 downloads
144 views

The effects of age on performance of life-history traits are diverse, but a common outcome is senescence, an irreversible deterioration of physical and physiological capabilities of older individuals. Immune response is potentially bound to senescence. However,...

["Developmental Biology","Ecology","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.6104
138 downloads
741 views

Bumble bees (Hymenoptera: Apidae, Bombus) are important pollinators and models for studying mechanisms underlying developmental plasticity, such as factors influencing size, immunity, and social behaviors. Research on such processes, as well as expanding use of...

["Agricultural Science","Developmental Biology","Entomology","Taxonomy"]
doi:10.7717/peerj.6089
37 downloads
266 views

Blue crabs, Callinectes sapidus Rathbun, 1896, are ubiquitous along the Atlantic and Gulf coasts of the USA. These organisms play an integral role in the ecosystems of the Gulf of Mexico (GOM), where not only are they a keystone species, but are also socioeconomically...

["Developmental Biology","Marine Biology","Toxicology","Ecotoxicology","Environmental Impacts"]
doi:10.7717/peerj.5985
125 downloads
544 views

Background In recent years, there has been a rapidly growing demand for readily accessible substrates for mass production of Black Soldier Fly, Hermetia illucens Linnaeus. Beer production results in various by-products that typically end up in uncontrolled dumpsites...

["Agricultural Science","Developmental Biology","Ecology","Entomology"]
doi:10.7717/peerj.5885
72 downloads
252 views

Background Sustainable methods of propagation of Typha domingensis through somatic embryogenesis can help mitigate its current condition of ecological marginalization and overexploitation. This study examined whether differentiation up to coleoptilar embryos could...

["Biotechnology","Developmental Biology","Histology","Freshwater Biology"]
doi:10.7717/peerj.5952
191 downloads
588 views

The reproductive biology of the Myristica Swamp tree frog (Mercurana myristicapalustris), a monotypic rhacophorid frog endemic to the foothills of the Western Ghats mountains of India, has remained unknown since the description of the genus and species. We monitored...

["Animal Behavior","Conservation Biology","Developmental Biology","Ecology","Zoology"]
doi:10.7717/peerj.5934
86 downloads
392 views

Articular cartilage is an avascular tissue with limited regenerative property. Therefore, a defect or trauma in articular cartilage due to disease or accident can lead to progressive tissue deterioration. Cartilage tissue engineering, by replacing defective cartilage...

["Bioengineering","Biotechnology","Cell Biology","Developmental Biology","Translational Medicine"]
doi:10.7717/peerj.5809
69 downloads
486 views

Individual differences in performances on cognitive tasks have been found to differ according to social rank across multiple species. However, it is not clear whether an individual’s cognitive performance is flexible and the result of their current social rank,...

["Animal Behavior","Developmental Biology","Zoology"]
doi:10.7717/peerj.5738
147 downloads
1,214 views

Teeth have been a focus of research in both extinct and extant taxa alike; a significant portion of dental literature is concerned with dental patterning and replacement. Most non-mammalian vertebrates continuously replace their dentition but an anomalous group...

["Developmental Biology","Zoology","Histology"]
doi:10.7717/peerj.5923
90 downloads
330 views

Since the early 20th century, European eels (Anguilla anguilla L.) have been dichotomously classified into ‘narrow’ and ‘broad’ heads. These morphs are mainly considered the result of a differential food choice, with narrow heads feeding primarily on small/soft...

["Animal Behavior","Developmental Biology"]
doi:10.7717/peerj.5773
80 downloads
278 views

Mitochondrial pyruvate carrier 1 (MPC1) is a component of the MPC1/MPC2 heterodimer that facilitates the transport of pyruvate into mitochondria. Pyruvate plays a central role in carbohydrate, fatty, and amino acid catabolism. The present study examined epididymal...

["Cell Biology","Developmental Biology","Molecular Biology"]
doi:10.7717/peerj.5799
144 downloads
848 views

Congenital heart disease (CHD) affects a considerable number of children and adults worldwide. This implicates not only developmental disorders, high mortality, and reduced quality of life but also, high costs for the healthcare systems. CHD refers to a variety...

["Cell Biology","Developmental Biology","Anatomy and Physiology","Cardiology","Pathology"]
doi:10.7717/peerj.5805

Refine by manuscript type

Top subject areas - Articles

Top subject areas - People

View all subject areas