Peer-reviewed Articles - Biology

43 downloads
238 views

Late embryogenesis abundant (LEA) proteins accumulate in plants during adverse conditions and their main attributed function is to confer tolerance to stress. One of the deleterious effects of the adverse environment is the accumulation of metal ions to levels...

["Biochemistry","Biophysics","Plant Science"]
doi:10.7717/peerj.4930
75 downloads
381 views

Elucidating the molecular mechanism of helix–coil transitions of short peptides is a long-standing conundrum in physical chemistry. Although the helix–coil transitions of poly-glutamic acid (PGA) have been extensively studied, the molecular details of its unfolding...

["Biophysics","Computational Biology"]
doi:10.7717/peerj.4769
82 downloads
305 views

Background 1,4-dihydropyridines (1,4-DHP) possesses important biochemical and pharmacological properties, including antioxidant and antimutagenic activities. It was shown that the antimutagenic 1,4-dihydropyridine AV-153-Na interacts with DNA. The aim of the current...

["Biophysics","Cell Biology","Molecular Biology"]
doi:10.7717/peerj.4609
91 downloads
642 views

Background There is convincing evidence for the benefits of resistance training on vertical jump improvements, but little evidence to guide optimal training prescription. The inability to detect small between modality effects may partially reflect the use of ANOVA...

["Biophysics","Kinesiology"]
doi:10.7717/peerj.4620
1 citation
99 downloads
527 views

The palm borer moth Paysandisia archon (Castniidae; giant butterfly-moths) has brown dorsal forewings and strikingly orange-coloured dorsal hindwings with white spots surrounded by black margins. Here, we have studied the structure and pigments of the wing scales...

["Biophysics","Entomology"]
doi:10.7717/peerj.4590
1 citation
121 downloads
801 views

The binding specificity of botulinum neurotoxins (BoNTs) is primarily a consequence of their ability to bind to multiple receptors at the same time. BoNTs consist of three distinct domains, a metalloprotease light chain (LC), a translocation domain (HN) and a receptor-binding...

["Biochemistry","Biophysics","Microbiology"]
doi:10.7717/peerj.4552
89 downloads
757 views

Objective In the foveola of the eye, photoreceptors and Müller cells with a unique morphology have been described, but little is known about their 3D structure and orientation. Considering that there is an angle-dependent change in the foveolar photoreceptor response...

["Biophysics","Cell Biology","Anatomy and Physiology","Ophthalmology","Histology"]
doi:10.7717/peerj.4482
106 downloads
528 views

The structure-thermodynamics correlation analysis was performed for a series of fluorine- and chlorine-substituted benzenesulfonamide inhibitors binding to several human carbonic anhydrase (CA) isoforms. The total of 24 crystal structures of 16 inhibitors bound...

["Biophysics","Drugs and Devices"]
doi:10.7717/peerj.4412
75 downloads
587 views

Osmolytes and macromolecular crowders have the potential to influence the stability of secondary structure motifs and alter preferences for conserved nucleic acid sequences in vivo. To further understand the cellular function of RNA we observed the effects of a...

["Biochemistry","Biophysics"]
doi:10.7717/peerj.4236
187 downloads
803 views

Background N-acetylcarnosine (NAC), a dipeptide with powerful antioxidant properties that is extensively used as a pharmaceutical prodrug for the treatment of cataract and acute gastric disease, was investigated by molecular dynamics with the GROMACS program in...

["Bioengineering","Biophysics","Computational Science"]
doi:10.7717/peerj.4270
93 downloads
447 views

The genome of the chlorarchiniophyte Bigelowiella natans codes for a protein annotated as an α-actinin-like protein. Analysis of the primary sequence indicate that this protein has the same domain structure as other α-actinins, a N-terminal actin-binding domain...

["Biochemistry","Biophysics","Developmental Biology"]
doi:10.7717/peerj.4288
149 downloads
749 views

Coarse-grained (CG) models have been successful in simulating the chemical properties of lipid bilayers, but accurate treatment of membrane proteins and lipid-protein molecular interactions remains a challenge. The CgProt force field, original developed with the...

["Biophysics","Computational Biology","Computational Science"]
doi:10.7717/peerj.4230
1 citation
187 downloads
749 views

Mushrooms are recognized as one of the main contributors to internal radiation exposure from the activity concentration of radiocesium released by the accident at the Chernobyl nuclear power plant (CNNP). We evaluated the activity concentrations of the artificial...

["Biochemistry","Biophysics","Environmental Sciences","Mycology","Public Health"]
doi:10.7717/peerj.4222
115 downloads
1,078 views

A frequency ratio of about 1.06 often appears in cochlear mechanics, and the question naturally arises, why? The ratio is close to that of the semitone (1.059) in music, giving reason to think that this aspect of musical perception might have a cochlear basis....

["Biophysics","Neuroscience","Anatomy and Physiology","Otorhinolaryngology"]
doi:10.7717/peerj.4192
85 downloads
484 views

The microtubule depolymerising kinesin-13, MCAK, is phosphorylated at residue T537 by Cdk1. This is the only known phosphorylation site within MCAK’s motor domain. To understand the impact of phosphorylation by Cdk1 on microtubule depolymerisation activity, we...

["Biochemistry","Biophysics","Molecular Biology"]
doi:10.7717/peerj.4034

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