Peer-reviewed Articles - Biology

74 downloads
419 views

Background A review of the literature has indicated that lower body stiffness, defined as the extent to which the lower extremity joints resists deformation upon contact with the ground, may be a useful measure for assessing Achilles injury risk in triathletes....

["Biophysics","Kinesiology"]
doi:10.7717/peerj.5845
196 downloads
3,080 views

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two late onset neurodegenerative diseases, have been shown to share overlapping cellular pathologies and genetic origins. Studies suggest that a hexanucleotide repeat expansion in the first...

["Biochemistry","Biophysics","Molecular Biology"]
doi:10.7717/peerj.5815
57 downloads
223 views

The number of amino acids that occupy a given protein site during evolution reflects the selective constraints operating on the site. This evolutionary variability is strongly influenced by the structural properties of the site in the native structure, and it is...

["Bioinformatics","Biophysics","Computational Biology","Evolutionary Studies"]
doi:10.7717/peerj.5549
69 downloads
284 views

Proteins of the DUF866 superfamily are exclusively found in eukaryotic cells. A member of the DUF866 superfamily, C1ORF123, is a human protein found in the open reading frame 123 of chromosome 1. The physiological role of C1ORF123 is yet to be determined. The only...

["Biochemistry","Biophysics","Cell Biology","Molecular Biology"]
doi:10.7717/peerj.5377
76 downloads
642 views

Natural aquatic environments such as oceans, lakes, and rivers are home to a tremendous diversity of microorganisms. Some may cross the air-water interface within droplets and become airborne, with the potential to impact the Earth’s radiation budget, precipitation...

["Biophysics","Microbiology","Freshwater Biology","Ecohydrology"]
doi:10.7717/peerj.5663
70 downloads
261 views

The ε subunit from ATP synthases acts as an ATP sensor in the bacterial cell to prevent ATP hydrolysis and thus the waste of ATP under conditions of low ATP concentration. However, the ATP binding affinities from various bacterial organisms differ markedly, over...

["Biophysics","Computational Biology","Molecular Biology"]
doi:10.7717/peerj.5505
49 downloads
273 views

Background Previous research suggests motion induced fatigue contributes to significant performance degradation and is likely related to a higher incidence of accidents and injuries. However, the exact effect of continuous multidirectional platform perturbations...

["Biophysics","Kinesiology","Metabolic Sciences"]
doi:10.7717/peerj.5439
88 downloads
405 views

The TonB protein plays an essential role in the energy transduction system to drive active transport across the outer membrane (OM) using the proton-motive force of the cytoplasmic membrane of Gram-negative bacteria. The C-terminal domain (CTD) of TonB protein...

["Biochemistry","Biophysics","Microbiology"]
doi:10.7717/peerj.5412
175 downloads
1,003 views

The CHARMM36 force field for lipids is widely used in simulations of lipid bilayers. The CHARMM family of force fields were developed for use with the mTIP3P water model. This water model has an anomalously high dielectric constant and low viscosity, which limits...

["Biochemistry","Biophysics","Computational Biology"]
doi:10.7717/peerj.5472
113 downloads
434 views

Cecropins, originally found in insects, are a group of cationic antimicrobial peptides. Most cecropins have an amphipathic N-terminal segment and a largely hydrophobic C-terminal segment, and normally form a helix-hinge-helix structure. In this study, we developed...

["Biochemistry","Biophysics"]
doi:10.7717/peerj.5369
138 downloads
610 views

Late embryogenesis abundant (LEA) proteins accumulate in plants during adverse conditions and their main attributed function is to confer tolerance to stress. One of the deleterious effects of the adverse environment is the accumulation of metal ions to levels...

["Biochemistry","Biophysics","Plant Science"]
doi:10.7717/peerj.4930
125 downloads
634 views

Elucidating the molecular mechanism of helix–coil transitions of short peptides is a long-standing conundrum in physical chemistry. Although the helix–coil transitions of poly-glutamic acid (PGA) have been extensively studied, the molecular details of its unfolding...

["Biophysics","Computational Biology"]
doi:10.7717/peerj.4769
124 downloads
488 views

Background 1,4-dihydropyridines (1,4-DHP) possesses important biochemical and pharmacological properties, including antioxidant and antimutagenic activities. It was shown that the antimutagenic 1,4-dihydropyridine AV-153-Na interacts with DNA. The aim of the current...

["Biophysics","Cell Biology","Molecular Biology"]
doi:10.7717/peerj.4609
127 downloads
1,036 views

Background There is convincing evidence for the benefits of resistance training on vertical jump improvements, but little evidence to guide optimal training prescription. The inability to detect small between modality effects may partially reflect the use of ANOVA...

["Biophysics","Kinesiology"]
doi:10.7717/peerj.4620
2 citations
161 downloads
815 views

The palm borer moth Paysandisia archon (Castniidae; giant butterfly-moths) has brown dorsal forewings and strikingly orange-coloured dorsal hindwings with white spots surrounded by black margins. Here, we have studied the structure and pigments of the wing scales...

["Biophysics","Entomology"]
doi:10.7717/peerj.4590

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