Peer-reviewed Articles - Biology

Orf, caused by Orf virus (ORFV), is a globally distributed zoonotic disease responsible for serious economic losses in the agricultural sector. However, the mechanism underlying ORFV infection remains largely unknown. Circular RNAs (circRNAs), a novel type of endogenous...

["Bioinformatics","Molecular Biology","Virology"]
doi:10.7717/peerj.6267
29 downloads
164 views

Six candidate reference genes were chosen from the transcriptome database of Radopholus similis using the bioinformatics method, including four conventional reference genes (actin, Eukaryotic translation initiation factor 5A (eIF5A), Tubulin alpha (a-tubulin),...

["Agricultural Science","Bioinformatics","Molecular Biology"]
doi:10.7717/peerj.6253
24 downloads
85 views

Background It has been well known that the degeneration of hip articular cartilage with osteonecrosis of the femoral head (ONFH) increases the instability of hip and accelerates the development process of ONFH. A better understanding of the expression of chondrogenesis-related...

["Bioinformatics","Orthopedics"]
doi:10.7717/peerj.6306
25 downloads
191 views

In a previous report, we explored the serverless OpenHealth approach to the Web as a Global Compute space. That approach relies on the modern browser full stack, and, in particular, its configuration for application assembly by code injection. The opportunity,...

["Bioinformatics","Epidemiology","Public Health","Computational Science","Data Science"]
doi:10.7717/peerj.6230
40 downloads
275 views

The co-occurrence of plant species is a fundamental aspect of plant ecology that contributes to understanding ecological processes, including the establishment of ecological communities and its applications in biological conservation. A priori algorithms can be...

["Bioinformatics","Ecology","Computational Science","Data Mining and Machine Learning","Spatial and Geographic Information Science"]
doi:10.7717/peerj.6193
41 downloads
240 views

Background The Streptococcus genus is relevant to both public health and food safety because of its ability to cause pathogenic infections. It is well-represented (>100 genomes) in publicly available databases. Streptococci are ubiquitous, with multiple sources...

["Biodiversity","Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7717/peerj.6233
35 downloads
207 views

Miniature inverted-repeat transposable elements (MITEs) have been associated with genic regions in plant genomes and may play important roles in the regulation of nearby genes via recruitment of small RNAs (sRNA) to the MITEs loci. We identified eight families...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7717/peerj.6080
78 downloads
520 views

Wild plant populations may harbour a myriad of unknown viruses. As the majority of research efforts have targeted economically important plant species, the diversity and prevalence of viruses in the wild has remained largely unknown. However, the recent shift towards...

["Bioinformatics","Ecology","Plant Science","Virology","Population Biology"]
doi:10.7717/peerj.6140
39 downloads
249 views

Antibodies are proteins generated by the adaptive immune system to recognize and counteract a plethora of pathogens through specific binding. This adaptive binding is mediated by structural diversity in the six complementary determining region (CDR) loops (H1,...

["Bioinformatics","Computational Biology"]
doi:10.7717/peerj.6179
33 downloads
145 views

Helicobacter pylori is a human pathogenic bacterium with a high genomic plasticity. Although the functional CRISPR-Cas system has not been found in its genome, CRISPR-like loci have been recently identified. In this work, 53 genomes from different geographical...

["Bioinformatics","Evolutionary Studies","Genetics","Genomics"]
doi:10.7717/peerj.6221
25 downloads
180 views

In polyploid genomes, homoeologs are a specific subtype of homologs, and can be thought of as orthologs between subgenomes. In Orthologous MAtrix, we infer homoeologs in three polyploid plant species: upland cotton (Gossypium hirsutum), rapeseed (Brassica napus),...

["Bioinformatics","Computational Biology","Genomics"]
doi:10.7717/peerj.6231
34 downloads
105 views

The MYB family, one of the largest transcription factor (TF) families in the plant kingdom, plays vital roles in cell formation, morphogenesis and signal transduction, as well as responses to biotic and abiotic stresses. However, the underlying function of bamboo...

["Bioinformatics","Genomics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.6242
31 downloads
190 views

Identifying cis-acting elements and understanding regulatory mechanisms of a gene is crucial to fully understand the molecular biology of an organism. In general, it is difficult to identify previously uncharacterised cis-acting elements with an unknown consensus...

["Bioinformatics","Evolutionary Studies","Genetics","Virology","Data Science"]
doi:10.7717/peerj.6176
396 downloads
4,863 views

Aggression is a serious behavioral disorder in domestic dogs that endangers both dogs and humans. The underlying causes of canine aggression are poorly resolved and require illumination to ensure effective therapy. Recent research links the compositional diversity...

["Animal Behavior","Bioinformatics","Microbiology"]
doi:10.7717/peerj.6103
43 downloads
220 views

Antimicrobial peptides (AMPs) are the main components of the plant innate immune system. Defensins represent the most important AMP family involved in defense and non-defense functions. In this work, global RNA sequencing and de novo transcriptome assembly were...

["Agricultural Science","Biodiversity","Bioinformatics","Genomics","Plant Science"]
doi:10.7717/peerj.6125

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