Peer-reviewed Articles - Medicine

1,114 downloads
9,839 views

Importance Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers’ full prescribing information (FPI) for finasteride and dutasteride state that risk...

["Dermatology","Epidemiology","Internal Medicine","Pharmacology","Urology"]
doi:10.7717/peerj.3020
118 downloads
319 views

Background Although the relationship between a history of kidney stones and chronic kidney disease (CKD) has been explored in many studies, it is still far from being well understood. Thus, we conducted a meta-analysis of studies comparing rates of CKD in patients...

["Epidemiology","Nephrology","Urology"]
doi:10.7717/peerj.2907
91 downloads
307 views

Purpose To clarify the outcome of flexible ureteroscopy (fURS) for management of renal calculi without preoperative stenting. Methods A total of 171 patients who received 176 fURS procedures for unilateral renal stones were reviewed. All procedures were divided...

["Urology"]
doi:10.7717/peerj.2728
64 downloads
247 views

Background Laparoscopic renal surgery has been widely used in the treatment of renal diseases. However, there is still little research about its application in addressing renal tuberculosis. The purpose of this study is to retrospectively investigate the surgical...

["Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.2708
93 downloads
924 views

Objective Bladder cancer is a cause of considerable morbidity worldwide. Electromotive Drug Administration is a method that combines intravesical chemotherapy with local electric field application. Electroporation has been suggested among other mechanisms as having...

["Biophysics","Drugs and Devices","Oncology","Radiology and Medical Imaging","Urology"]
doi:10.7717/peerj.2309
164 downloads
1,045 views

Objectives. The frequency, predisposing factors and impact of urinary incontinence (UI) on quality of life (QoL) during pregnancy were investigated. Materials and Method. A preliminary cross-sectional survey was studied among pregnant women between January and...

["Gynecology and Obstetrics","Health Policy","Nursing","Urology","Women\u2019s Health"]
doi:10.7717/peerj.2283
129 downloads
580 views

Background. Testicular ischemia reperfusion injury (tIRI) is considered the mechanism underlying the pathology of testicular torsion and detorsion. Left untreated, tIRI can induce testis dysfunction, damage to spermatogenesis and possible infertility. In this study,...

["Biochemistry","Molecular Biology","Anatomy and Physiology","Translational Medicine","Urology"]
doi:10.7717/peerj.2195
102 downloads
539 views

Background. Epidemiological studies have reported various results relating preoperative hydronephrosis to upper tract urothelial carcinoma (UTUC). However, the clinical significance and prognostic value of preoperative hydronephrosis in UTUC remains controversial....

["Evidence Based Medicine","Oncology","Public Health","Urology"]
doi:10.7717/peerj.2144
119 downloads
497 views

Urine is a very good source for biomarker discovery because it accumulates changes in the body. However, a major challenge in urinary biomarker discovery is the fact that the urinary proteome is influenced by various elements. To circumvent these problems, simpler...

["Biochemistry","Developmental Biology","Urology"]
doi:10.7717/peerj.2058
129 downloads
787 views

Background. Several factors have been validated as predictors of disease recurrence in upper tract urothelial carcinoma. However, the oncological outcomes between different surgical approaches (open nephroureterectomy versus laparoscopic nephroureterectomy, ONU...

["Nephrology","Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.2063
6 citations
223 downloads
859 views

Testosterone is overwhelmingly important in regulating erectile physiology. However, the associated molecular mechanisms are poorly understood. The purpose of this study was to explore the effects and mechanisms of testosterone in erectile dysfunction (ED) in castrated...

["Andrology","Diabetes and Endocrinology","Urology"]
doi:10.7717/peerj.2000
134 downloads
716 views

Background. Members of the Runx gene family encode transcription factors that bind to DNA in a sequence-specific manner. Among the three Runx proteins, Runx2 comprises 607 amino acid (aa) residues, is expressed in bone, and plays crucial roles in osteoblast differentiation...

["Andrology","Urology"]
doi:10.7717/peerj.1862
2 citations
268 downloads
1,077 views

Background. MicroRNAs (miRNAs) influence a variety of biological functions by regulating gene expression post-transcriptionally. Aberrant miRNA expression has been associated with many human diseases. Urolithiasis is a common disease, and idiopathic hypercalciuria...

["Bioinformatics","Molecular Biology","Urology"]
doi:10.7717/peerj.1884
187 downloads
1,116 views

Background. Obesity has reached epidemic proportions in dogs and, as in humans, cost of care has increased due to associated comorbidities. In humans, asymptomatic urinary tract infections (UTI) may be more prevalent in the obese. Asymptomatic bacteriuria (AB)...

["Veterinary Medicine","Nutrition","Urology"]
doi:10.7717/peerj.1711
1 citation
162 downloads
650 views

Background. Prostate cancer makes up approximately 15% of all cancers diagnosed in men in developed nations and approximately 4% of cases in developing nations. Although it is clear that prostate cancer has a genetic component and single nucleotide polymorphisms...

["Oncology","Urology","Medical Genetics"]
doi:10.7717/peerj.1731

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