Peer-reviewed Articles - Medicine

16 downloads
154 views

Background and Purpose Oxidative stress is involved in normal and pathological functioning of skeletal muscle. Protection of myoblasts from oxidative stress may improve muscle contraction and delay aging. Here we studied the effect of R. coriaria sumac fruit extract...

["Cell Biology","Translational Medicine"]
doi:10.7717/peerj.4144
41 downloads
266 views

Objective Our previous genome-wide association study (GWAS) identified that the ABO rs633862 variant in chromosome 9q34.2 was associated with the risk of epithelial ovarian cancer (EOC) in Chinese Han women. The aim of the present study was to evaluate its prognostic...

["Oncology","Translational Medicine","Women\u2019s Health"]
doi:10.7717/peerj.3946
65 downloads
271 views

Bone marrow stimulation may be applied to regenerate focal cartilage defects, but generally results in transient clinical improvement and formation of fibrocartilage rather than hyaline cartilage. Tissue engineering and regenerative medicine strive to develop new...

["Bioengineering","Evidence Based Medicine","Orthopedics","Rheumatology","Translational Medicine"]
doi:10.7717/peerj.3927
112 downloads
408 views

Background Diabetes is one of the major risk factors for peripheral arterial disease. In patients in whom surgery cannot be performed, cell therapy may be an alternative treatment. Since time is crucial for these patients, we propose the use of allogenic mesenchymal...

["Surgery and Surgical Specialties","Translational Medicine"]
doi:10.7717/peerj.3664
164 downloads
548 views

Introduction Different types of headaches and TMJ click influence the masseter muscle activity. The aim of this study was to assess the trend of energy level of the electromyography (EMG) activity of the masseter muscle during open-close clench cycles in migraine...

["Bioengineering","Computational Biology","Evidence Based Medicine","Radiology and Medical Imaging","Translational Medicine"]
doi:10.7717/peerj.3556
106 downloads
619 views

The death-associated protein kinase 1 (DAPK1) can act as an oncogene or a tumor suppressor gene depending on the cellular context as well as external stimuli. Our study aims to investigate the prognostic significance of DAPK1 in liver cancer in both mRNA and protein...

["Biochemistry","Gastroenterology and Hepatology","Oncology","Translational Medicine","Histology"]
doi:10.7717/peerj.3568
130 downloads
780 views

Breast cancer spheroids have been widely used as in vitro models of cancer stem cells (CSCs), yet little is known about their phenotypic characteristics and microRNAs (miRNAs) expression profiles. The objectives of this research were to evaluate the phenotypic...

["Cell Biology","Molecular Biology","Translational Medicine"]
doi:10.7717/peerj.3551
1 citation
64 downloads
430 views

Background In humans, non-stereotactic frameless neuronavigation systems are used as a topographical tool for non-invasive brain stimulation methods such as Transcranial Magnetic Stimulation (TMS). TMS studies in dogs may provide treatment modalities for several...

["Animal Behavior","Neuroscience","Veterinary Medicine","Psychiatry and Psychology","Translational Medicine"]
doi:10.7717/peerj.3425
127 downloads
583 views

Background Adipose-derived mesenchymal stem cells (ADSCs) have shown great potential in the treatment of various diseases. However, the optimum short-term storage condition of ADSCs in 2∼8 °C is rarely reported. This study aimed at optimizing a short-term storage...

["Biotechnology","Cell Biology","Translational Medicine"]
doi:10.7717/peerj.3301
132 downloads
593 views

Background Treatments that target cancer stem cells play an important role in the controlling and eliminating of tumor initiation as well as in development, progression, and chemotherapy/radiotherapy resistance. In our previous study, we cultured and harvested...

["Oncology","Translational Medicine"]
doi:10.7717/peerj.3233
3 citations
120 downloads
605 views

Background Individuals with type 2 diabetes are at an increased risk of cardiovascular disease. Alterations in circulating lipid levels, total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TG) are heritable...

["Bioinformatics","Genomics","Diabetes and Endocrinology","Translational Medicine","Metabolic Sciences"]
doi:10.7717/peerj.3187
4 citations
179 downloads
520 views

Background Sevoflurane postconditioning (S-post) has similar cardioprotective effects as ischemic preconditioning. However, the underlying mechanism of S-post has not been fully elucidated. Janus kinase signaling transduction/transcription activator (JAK2–STAT3)...

["Anesthesiology and Pain Management","Cardiology","Translational Medicine"]
doi:10.7717/peerj.3196
210 downloads
1,018 views

Sensitivity of short read DNA-sequencing for gene fusion detection is improving, but is hampered by the significant amount of noise composed of uninteresting or false positive hits in the data. In this paper we describe a tiered prioritisation approach to extract...

["Bioinformatics","Genomics","Oncology","Translational Medicine"]
doi:10.7717/peerj.3166
1 citation
225 downloads
588 views

Background ABO blood group is a hereditary factor of plasma levels of coagulation factor VIII (FVIII) and von Willebrand factor (VWF). Age and gender have been shown to influence FVIII, VWF, fibrinogen (Fbg), and ADAMTS13 (A disintegrin and metalloprotease with...

["Biochemistry","Global Health","Hematology","Translational Medicine"]
doi:10.7717/peerj.3156
2 citations
189 downloads
507 views

The low survival rate of cardiac stem cells (CSCs) in the ischemic myocardium is one of the obstacles in ischemic cardiomyopathy cell therapy. The MicroRNA (miR)-21 and one of its target protein, the tensin homolog deleted on chromosome ten (PTEN), contributes...

["Cell Biology","Cardiology","Translational Medicine"]
doi:10.7717/peerj.2859

Top subject areas - Articles

Top subject areas - People

View all subject areas