Peer-reviewed Articles - Medicine

284 downloads
783 views

Some evidence suggests that bone health can be regulated by gut microbiota. To better understand this, we performed 16S ribosomal RNA sequencing to analyze the intestinal microbial diversity in primary osteoporosis (OP) patients, osteopenia (ON) patients and normal...

["Microbiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3450
190 downloads
996 views

Gastrocnemius-soleus equinus (GSE) is a foot-ankle complaint in which the extensibility of the gastrocnemius (G) and soleus muscles (triceps surae) and ankle are limited to a dorsiflexion beyond a neutral ankle position. The asymmetric forces of leg muscles and...

["Kinesiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3388
58 downloads
413 views

Introduction Osteoarthritis (OA) is one of the most common causes of musculoskeletal system’s ailments. In the prevention of the disease and in its comprehensive treatment, proper health-related behavior becomes an extremely important factor for maintaining an...

["Epidemiology","Nursing","Orthopedics","Rheumatology","Science and Medical Education"]
doi:10.7717/peerj.3276
160 downloads
514 views

Objective This study aimed to quantify the cartilage- and subchondral bone-related effects of low-dose and high-dose meloxicam treatment in the late phase of mono-iodoacetate-induced osteoarthritis of the stifle. Methods Thirty-four male Wistar rats received intra-articular...

["Pathology","Pharmacology","Rheumatology","Histology"]
doi:10.7717/peerj.3185
172 downloads
699 views

Background Rheumatoid arthritis (RA) is a chronic auto-inflammatory disorder of joints. The present study aimed to identify the key genes in RA for better understanding the underlying mechanisms of RA. Methods The integrated analysis of expression profiling was...

["Bioinformatics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3078
88 downloads
517 views

Interstitial lung disease (ILD) is a severe extra-articular manifestation of rheumatoid arthritis (RA) that is well-defined as a chronic systemic autoimmune disease. A proportion of patients with RA-associated ILD (RA-ILD) develop pulmonary fibrosis (PF), resulting...

["Immunology","Respiratory Medicine","Rheumatology","Statistics"]
doi:10.7717/peerj.3021
194 downloads
828 views

Background There is a high prevalence of non-specific shoulder pain associated with upper limb functional limitations in older adults. The purpose of this study was to determine the minimal clinically important differences (MCID) of grip strength and pressure pain...

["Geriatrics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.2995
126 downloads
510 views

Aims We have recently created an age-dependent hypertensive-mono-arthritic animal model from the stroke-resistant spontaneously hypertensive rat to model populations with autoimmune disease who are hypertensive and are prone to stroke. The model exhibits signs...

["Cardiology","Immunology","Pharmacology","Rheumatology","Histology"]
doi:10.7717/peerj.2608
2 citations
211 downloads
521 views

Introduction Rituximab (RTX) is a B cell-depleting agent approved for the treatment of granulomatosis with polyangiitis (GPA). RTX reduces antibody producing precursor plasma cells and inhibits B and T cells interaction. Infections related to T cell immunodeficiency...

["Allergy and Clinical Immunology","Internal Medicine","Rheumatology"]
doi:10.7717/peerj.2487
1 citation
381 downloads
907 views

Objective The current study is an innovative exploratory investigation, aiming at identifying differences in personality profiles within Fibromyalgia Syndrome (FMS) and Chronic Fatigue Syndrome (CFS) patients. Method In total, 344 participants (309 female, 35 male)...

["Anaesthesiology and Pain Management","Psychiatry and Psychology","Rheumatology"]
doi:10.7717/peerj.2421
2 citations
512 downloads
956 views

Microfracture surgery may be applied to treat cartilage defects. During the procedure the subchondral bone is penetrated, allowing bone marrow-derived mesenchymal stem cells to migrate towards the defect site and form new cartilage tissue. Microfracture surgery...

["Bioengineering","Orthopedics","Rheumatology","Translational Medicine"]
doi:10.7717/peerj.2243
2 citations
238 downloads
1,136 views

Background. A loss of mucosal tolerance to the resident microbiome has been postulated in the aetiopathogenesis of spondyloarthritis, thus the purpose of these studies was to investigate microbial communities that colonise the oral cavity of patients with axial...

["Microbiology","Dentistry","Rheumatology"]
doi:10.7717/peerj.2095
1 citation
654 downloads
1,050 views

Background: Fibromyalgia is a syndrome characterized by the presence of widespread chronic pain. People with fibromyalgia report lower levels of Positive Affect and higher levels of Negative Affect than non-fibromyalgia peers. The Positive and Negative Affect Schedule...

["Psychiatry and Psychology","Rheumatology","Women\u2019s Health"]
doi:10.7717/peerj.1822
305 downloads
1,346 views

Background. Hand function is essential to a person’s self-efficacy and greatly affects quality of life. Adapted utensils with handles of increased diameters have historically been used to assist individuals with arthritis or other hand disabilities for feeding,...

["Kinesiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.1667
4 citations
156 downloads
1,206 views

Background and Objectives. The accessory head of the flexor pollicis longus muscle (AHFPL), also known as the Gantzer’s muscle, was first described in 1813. The prevalence rates of an AHFPL significantly vary between studies, and no consensus has been reached on...

["Anatomy and Physiology","Evidence Based Medicine","Kinesiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.1255

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