Peer-reviewed Articles - Medicine

45 downloads
352 views

Background Rheumatoid arthritis (RA) is a chronic auto-inflammatory disorder of joints. The present study aimed to identify the key genes in RA for better understanding the underlying mechanisms of RA. Methods The integrated analysis of expression profiling was...

["Bioinformatics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3078
52 downloads
288 views

Interstitial lung disease (ILD) is a severe extra-articular manifestation of rheumatoid arthritis (RA) that is well-defined as a chronic systemic autoimmune disease. A proportion of patients with RA-associated ILD (RA-ILD) develop pulmonary fibrosis (PF), resulting...

["Immunology","Respiratory Medicine","Rheumatology","Statistics"]
doi:10.7717/peerj.3021
108 downloads
537 views

Background There is a high prevalence of non-specific shoulder pain associated with upper limb functional limitations in older adults. The purpose of this study was to determine the minimal clinically important differences (MCID) of grip strength and pressure pain...

["Geriatrics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.2995
82 downloads
397 views

Aims We have recently created an age-dependent hypertensive-mono-arthritic animal model from the stroke-resistant spontaneously hypertensive rat to model populations with autoimmune disease who are hypertensive and are prone to stroke. The model exhibits signs...

["Cardiology","Immunology","Pharmacology","Rheumatology","Histology"]
doi:10.7717/peerj.2608
1 citation
150 downloads
411 views

Introduction Rituximab (RTX) is a B cell-depleting agent approved for the treatment of granulomatosis with polyangiitis (GPA). RTX reduces antibody producing precursor plasma cells and inhibits B and T cells interaction. Infections related to T cell immunodeficiency...

["Allergy and Clinical Immunology","Internal Medicine","Rheumatology"]
doi:10.7717/peerj.2487
332 downloads
727 views

Objective The current study is an innovative exploratory investigation, aiming at identifying differences in personality profiles within Fibromyalgia Syndrome (FMS) and Chronic Fatigue Syndrome (CFS) patients. Method In total, 344 participants (309 female, 35 male)...

["Anaesthesiology and Pain Management","Psychiatry and Psychology","Rheumatology"]
doi:10.7717/peerj.2421
1 citation
412 downloads
732 views

Microfracture surgery may be applied to treat cartilage defects. During the procedure the subchondral bone is penetrated, allowing bone marrow-derived mesenchymal stem cells to migrate towards the defect site and form new cartilage tissue. Microfracture surgery...

["Bioengineering","Orthopedics","Rheumatology","Translational Medicine"]
doi:10.7717/peerj.2243
2 citations
191 downloads
938 views

Background. A loss of mucosal tolerance to the resident microbiome has been postulated in the aetiopathogenesis of spondyloarthritis, thus the purpose of these studies was to investigate microbial communities that colonise the oral cavity of patients with axial...

["Microbiology","Dentistry","Rheumatology"]
doi:10.7717/peerj.2095
1 citation
512 downloads
895 views

Background: Fibromyalgia is a syndrome characterized by the presence of widespread chronic pain. People with fibromyalgia report lower levels of Positive Affect and higher levels of Negative Affect than non-fibromyalgia peers. The Positive and Negative Affect Schedule...

["Psychiatry and Psychology","Rheumatology","Women\u2019s Health"]
doi:10.7717/peerj.1822
234 downloads
1,072 views

Background. Hand function is essential to a person’s self-efficacy and greatly affects quality of life. Adapted utensils with handles of increased diameters have historically been used to assist individuals with arthritis or other hand disabilities for feeding,...

["Kinesiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.1667
3 citations
130 downloads
1,060 views

Background and Objectives. The accessory head of the flexor pollicis longus muscle (AHFPL), also known as the Gantzer’s muscle, was first described in 1813. The prevalence rates of an AHFPL significantly vary between studies, and no consensus has been reached on...

["Anatomy and Physiology","Evidence Based Medicine","Kinesiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.1255
1 citation
166 downloads
938 views

Objective. Chronic nasal carriage of Staphylococcus aureus (SA) increases the risk of relapse while Rituximab (RTX) is an effective agent for inducing and maintaining remission in patients with Granulomatosis with polyangiitis (GPA). We investigated whether B cell...

["Allergy and Clinical Immunology","Immunology","Infectious Diseases","Internal Medicine","Rheumatology"]
doi:10.7717/peerj.1051
2 citations
228 downloads
717 views

To comprehensively evaluate the association between rs7517847 and rs2201841 polymorphisms in the Interleukin-23 (IL-23) receptor gene and ankylosing spondylitis (AS), a meta-analysis was performed. The Pubmed, Embase, MEDLINE, Cochrane, China National Knowledge...

["Genetics","Orthopedics","Rheumatology","Statistics"]
doi:10.7717/peerj.910
5 citations
253 downloads
1,102 views

Chronic pain due to osteoarthritis (OA) can lead to significant disruption of sleep and increased restlessness. Our objective was to assess whether naturally occurring canine OA is associated with nighttime restlessness and so has potential as a model of OA-associated...

["Veterinary Medicine","Anaesthesiology and Pain Management","Orthopedics","Rheumatology"]
doi:10.7717/peerj.772
2 citations
257 downloads
1,173 views

To determine effects of intraarticularly administered tiludronate on articular cartilage in vivo, eight healthy horses were injected once with tiludronate (low dose tiludronate [LDT] 0.017 mg, n = 4; high dose tiludronate [HDT] 50 mg, n = 4) into one middle carpal...

["Veterinary Medicine","Drugs and Devices","Rheumatology"]
doi:10.7717/peerj.534

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