Peer-reviewed Articles - Medicine

20 downloads
180 views

Objective Osteoarthritis (OA) is a disease characterized by degeneration of joint cartilage. It is associated with pain and disability and is the result of either age and activity related joint wear or an injury. Non-invasive treatment options are scarce and prevention...

["Mathematical Biology","Orthopedics"]
doi:10.7717/peerj.3468
46 downloads
216 views

Transpedicular transdiscal screw fixation is an alternative technique used in lumbar spine fixation; however, it requires an accurate screw trajectory. The aim of this study is to design a novel 3D-printed custom drill guide and investigate its accuracy to guide...

["Bioengineering","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3564
39 downloads
233 views

Background Osteoprotegerin (OPG) is used for the systemic treatment of bone diseases, although it has many side effects. The aim of this study was to investigate a newly formulated OPG-chitosan gel for local application to repair bone defects. Recent studies have...

["Bioengineering","Orthopedics","Pharmacology"]
doi:10.7717/peerj.3513
82 downloads
657 views

This paper uses X-ray computed tomography to track the mechanical response of a vertebrate (Barnacle goose) long bone subjected to an axial compressive load, which is increased gradually until failure. A loading rig was mounted in an X-ray computed tomography system...

["Bioengineering","Kinesiology","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3416
266 downloads
715 views

Some evidence suggests that bone health can be regulated by gut microbiota. To better understand this, we performed 16S ribosomal RNA sequencing to analyze the intestinal microbial diversity in primary osteoporosis (OP) patients, osteopenia (ON) patients and normal...

["Microbiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3450
178 downloads
932 views

Gastrocnemius-soleus equinus (GSE) is a foot-ankle complaint in which the extensibility of the gastrocnemius (G) and soleus muscles (triceps surae) and ankle are limited to a dorsiflexion beyond a neutral ankle position. The asymmetric forces of leg muscles and...

["Kinesiology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3388
74 downloads
277 views

Background Low back pain (LBP) is the most common problem worldwide. There are several negative consequences of LBP, such as sleep disorders, work leave, disability, depression, anxiety, and poor quality of life. In this study, we designed to evaluate the prevalence...

["Kinesiology","Neurology","Orthopedics"]
doi:10.7717/peerj.3282
55 downloads
396 views

Introduction Osteoarthritis (OA) is one of the most common causes of musculoskeletal system’s ailments. In the prevention of the disease and in its comprehensive treatment, proper health-related behavior becomes an extremely important factor for maintaining an...

["Epidemiology","Nursing","Orthopedics","Rheumatology","Science and Medical Education"]
doi:10.7717/peerj.3276
119 downloads
1,093 views

Background Kettlebell lifting has gained increased popularity as both a form of resistance training and as a sport, despite the paucity of literature validating its use as a training tool. Kettlebell sport requires participants to complete the kettlebell snatch...

["Bioengineering","Anatomy and Physiology","Kinesiology","Orthopedics"]
doi:10.7717/peerj.3111
139 downloads
542 views

Background Cartilage tissue engineering is a fast-evolving field of biomedical engineering, in which the chondrocytes represent the most commonly used cell type. Since research in tissue engineering always consumes a lot of cells, simple and cheap isolation methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.3079
150 downloads
656 views

Background Rheumatoid arthritis (RA) is a chronic auto-inflammatory disorder of joints. The present study aimed to identify the key genes in RA for better understanding the underlying mechanisms of RA. Methods The integrated analysis of expression profiling was...

["Bioinformatics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3078
185 downloads
793 views

Background There is a high prevalence of non-specific shoulder pain associated with upper limb functional limitations in older adults. The purpose of this study was to determine the minimal clinically important differences (MCID) of grip strength and pressure pain...

["Geriatrics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.2995
78 downloads
377 views

The fibrosis that develops following laminectomy or discectomy often causes serious complications, and the proliferation of fibroblasts is thought to be the major cause of epidural fibrosis. 10-Hydroxycamptothecin (HCPT) has been proven to be efficient in preventing...

["Cell Biology","Orthopedics","Pharmacology","Histology"]
doi:10.7717/peerj.2858
284 downloads
590 views

Background Electrical stimulation (ES) has been successfully used to treat bone defects clinically. Recently, both cellular and molecular approaches have demonstrated that ES can change cell behavior such as migration, proliferation and differentiation. Methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.2821
1 citation
218 downloads
738 views

Introduction Osteoporosis is becoming an impending epidemic in the Asia-Pacific region. The association between risk of osteoporotic fracture (OTPF) and chronic obstructive pulmonary disease (COPD) in East Asian patients is yet to be fully examined. We conducted...

["Epidemiology","Geriatrics","Global Health","Orthopedics","Respiratory Medicine"]
doi:10.7717/peerj.2634

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