Peer-reviewed Articles - Medicine

36 downloads
258 views

Background Cartilage tissue engineering is a fast-evolving field of biomedical engineering, in which the chondrocytes represent the most commonly used cell type. Since research in tissue engineering always consumes a lot of cells, simple and cheap isolation methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.3079
53 downloads
363 views

Background Rheumatoid arthritis (RA) is a chronic auto-inflammatory disorder of joints. The present study aimed to identify the key genes in RA for better understanding the underlying mechanisms of RA. Methods The integrated analysis of expression profiling was...

["Bioinformatics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3078
108 downloads
537 views

Background There is a high prevalence of non-specific shoulder pain associated with upper limb functional limitations in older adults. The purpose of this study was to determine the minimal clinically important differences (MCID) of grip strength and pressure pain...

["Geriatrics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.2995
52 downloads
243 views

The fibrosis that develops following laminectomy or discectomy often causes serious complications, and the proliferation of fibroblasts is thought to be the major cause of epidural fibrosis. 10-Hydroxycamptothecin (HCPT) has been proven to be efficient in preventing...

["Cell Biology","Orthopedics","Pharmacology","Histology"]
doi:10.7717/peerj.2858
138 downloads
353 views

Background Electrical stimulation (ES) has been successfully used to treat bone defects clinically. Recently, both cellular and molecular approaches have demonstrated that ES can change cell behavior such as migration, proliferation and differentiation. Methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.2821
164 downloads
573 views

Introduction Osteoporosis is becoming an impending epidemic in the Asia-Pacific region. The association between risk of osteoporotic fracture (OTPF) and chronic obstructive pulmonary disease (COPD) in East Asian patients is yet to be fully examined. We conducted...

["Epidemiology","Geriatrics","Global Health","Orthopedics","Respiratory Medicine"]
doi:10.7717/peerj.2634
90 downloads
701 views

The present study investigated the effects of grip on changes in the median nerve cross-sectional area (MNCSA) and median nerve diameter in the radial-ulnar direction (D1) and dorsal-palmar direction (D2) at three wrist angles. Twenty-nine healthy participants...

["Kinesiology","Neurology","Orthopedics"]
doi:10.7717/peerj.2510
1 citation
414 downloads
734 views

Microfracture surgery may be applied to treat cartilage defects. During the procedure the subchondral bone is penetrated, allowing bone marrow-derived mesenchymal stem cells to migrate towards the defect site and form new cartilage tissue. Microfracture surgery...

["Bioengineering","Orthopedics","Rheumatology","Translational Medicine"]
doi:10.7717/peerj.2243
139 downloads
519 views

Previous studies have shown that platelet concentrates used in conjunction with appropriate growth media enhance osteogenic differentiation of human mesenchymal stromal cells (hMSCs). However, their potential in inducing osteogenesis of hMSCs when cultured in serum...

["Cell Biology","Orthopedics","Translational Medicine"]
doi:10.7717/peerj.2347
295 downloads
1,038 views

Background While appropriate pillow height is crucial to maintaining the quality of sleep and overall health, there are no universal, evidence-based guidelines for pillow design or selection. We aimed to evaluate the effect of pillow height on cranio-cervical pressure...

["Bioengineering","Kinesiology","Orthopedics"]
doi:10.7717/peerj.2397
1 citation
230 downloads
916 views

Background Measurement of lumbar spine range of motion (ROM) is often considered to be an essential component of lumbar spine physiotherapy and orthopedic assessment. The measurement can be carried out through various instruments such as inclinometers, goniometers,...

["Anatomy and Physiology","Kinesiology","Orthopedics"]
doi:10.7717/peerj.2355
137 downloads
529 views

Background The receptor activator of nuclear factor kappa-B (RANK)/RANK ligand/osteoprotegerin (OPG) system plays a critical role in bone remodelling by regulating osteoclast formation and activity. OPG has been used systemically in the treatment of bone diseases....

["Bioengineering","Orthopedics","Pharmacology"]
doi:10.7717/peerj.2229
1,040 downloads
7,593 views

The modified Thomas test was developed to assess the presence of hip flexion contracture and to measure hip extensibility. Despite its widespread use, to the authors’ knowledge, its criterion reference validity has not yet been investigated. The purpose of this...

["Anatomy and Physiology","Kinesiology","Orthopedics"]
doi:10.7717/peerj.2325
169 downloads
681 views

Objective. Bone lesion is crucial for diagnosing and management of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin change (POEMS) syndrome, a rare plasma cell disorder. This study is to compare the effectiveness of X-ray skeletal survey...

["Hematology","Orthopedics","Radiology and Medical Imaging"]
doi:10.7717/peerj.2294
126 downloads
785 views

Background. Significant and/or complete rupture in the musculotendinous junction (MTJ) is a challenging lesion to treat because of the lack of reliable suture methods. Skeletal muscle-derived multipotent stem cell (Sk-MSC) sheet-pellets, which are able to reconstitute...

["Cell Biology","Anatomy and Physiology","Orthopedics","Translational Medicine"]
doi:10.7717/peerj.2231

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