Peer-reviewed Articles - Medicine

75 downloads
438 views

Major depressive disorder (MDD) is highly prevalent, recurrent, and associated with functional impairment, morbidity, and mortality. Herein, we aimed to identify disruptions in functional connectomics among subjects with MDD by using resting-state functional magnetic...

["Neuroscience","Cognitive Disorders","Neurology"]
doi:10.7717/peerj.3147
57 downloads
274 views

Peripheral nerves are extremely complex biological structures. The knowledge of their response to stretch is crucial to better understand physiological and pathological states (e.g., due to overstretch). Since their mechanical response is deterministically related...

["Bioengineering","Computational Biology","Neurology"]
doi:10.7717/peerj.4005
54 downloads
277 views

Hands motor imagery (MI) has been reported to alter synchronization patterns amongst neurons, yielding variations in the mu and beta bands’ power spectral density (PSD) of the electroencephalography (EEG) signal. These alterations have been used in the field of...

["Neuroscience","Neurology","Human-Computer Interaction","Computational Science"]
doi:10.7717/peerj.3983
58 downloads
250 views

Small interference RNA has been widely used to suppress gene expression. Three different short hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1), driven by mouse U6 promoter in self-complementary AAV8 vector (scAAV8), were used to silence mouse striatal...

["Neuroscience","Neurology","Pathology"]
doi:10.7717/peerj.3905
95 downloads
942 views

Language lateralisation refers to the phenomenon in which one hemisphere (typically the left) shows greater involvement in language functions than the other. Measurement of laterality is of interest both to researchers investigating the neural organisation of the...

["Neuroscience","Neurology","Psychiatry and Psychology","Radiology and Medical Imaging"]
doi:10.7717/peerj.3929
116 downloads
571 views

The purpose of this study was to investigate the benefits of exercises with different cognitive demands for cognitive functions (Executive and non-Executive) in healthy older adults. A cross-sectional design was adopted. In total, 84 healthy older adults were enrolled...

["Neuroscience","Geriatrics","Neurology","Ophthalmology"]
doi:10.7717/peerj.3943
134 downloads
482 views

Clinical evidence points to neuroprotective effects of smoking in Parkinson’s disease (PD), but the molecular mechanisms remain unclear. We investigated the pharmacological pathways involved in these neuroprotective effects, which could provide novel ideas for...

["Biochemistry","Molecular Biology","Neuroscience","Neurology","Pharmacology"]
doi:10.7717/peerj.3933
73 downloads
728 views

In the context of a hunt for a postulated hormone that is tissue-mass inhibiting and reproductively associated, there is described probable relatedness to a granin protein. A 7–8 kDa polypeptide candidate (gels/MS) appeared in a bioassay-guided fractionation campaign...

["Biochemistry","Cell Biology","Diabetes and Endocrinology","Neurology"]
doi:10.7717/peerj.3833
71 downloads
304 views

Background Cocaine use disorder (CUD) is a complex health condition, especially when it is accompanied by comorbid psychiatric disorders (dual diagnosis). Dual diagnosis is associated with difficulties in the stratification and treatment of patients. One of the...

["Cognitive Disorders","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.3926
58 downloads
475 views

Background Recently it has been shown in animal studies that deep brain stimulation (DBS) of auditory structures was able to reduce tinnitus-like behavior. However, the question arises whether hearing might be impaired when interfering in auditory-related network...

["Neurology","Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3892
75 downloads
323 views

Background We investigated EEG rhythms, particularly alpha activity, and their relationship to post-stroke neuropathology and cognitive functions in the subacute and chronic stages of minor strokes. Methods We included 10 patients with right middle cerebral artery...

["Cognitive Disorders","Neurology"]
doi:10.7717/peerj.3839
1 citation
94 downloads
638 views

Background The cause−effect relation between periodontal inflammatory disease (PID) and Parkinson’s disease (PD) remains uncertain. The purpose of our study was to investigate the association between PID and PD. Methods We conducted a retrospective matched-cohort...

["Dentistry","Epidemiology","Neurology","Public Health"]
doi:10.7717/peerj.3647
2 citations
190 downloads
1,204 views

The involvement of the right and left hemispheres in mediating language functions has been measured in a variety of ways over the centuries since the relative dominance of the left hemisphere was first known. Functional magnetic resonance imaging (fMRI) presents...

["Neuroscience","Neurology","Psychiatry and Psychology","Radiology and Medical Imaging"]
doi:10.7717/peerj.3557
122 downloads
592 views

Objective An acquired brain injury (ABI) is a challenge for an individual’s quality of life (QOL). In several chronic illnesses acceptance has been found to be associated with a better health-related quality of life. This study investigated whether this relationship...

["Cognitive Disorders","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.3545
99 downloads
621 views

Background Impulsivity is one crucial personality trait associated with various maladaptive behavior and many mental disorders. In the study reported here, we investigated the relationship between impulsivity and morphological connectivity (MC) between human brain...

["Neuroscience","Neurology","Psychiatry and Psychology","Radiology and Medical Imaging"]
doi:10.7717/peerj.3533

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