Peer-reviewed Articles - Medicine

100 downloads
426 views

A metabolomic study has been performed to identify sensitive and robust biomarkers of malnutrition in farmed fish, using gilthead sea bream (Sparus aurata) as a model. The metabolomic fingerprinting of serum from fasted fish was assessed by means of ultra-high...

["Aquaculture, Fisheries and Fish Science","Biochemistry","Bioinformatics","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.2920
157 downloads
422 views

Background Subcutaneous adipose tissue is a rich source of adipose tissue macrophages and adipose-derived stem cells which both play a key role in wound repair. While macrophages can be divided into the classically-activated M1 and the alternatively-activated M2...

["Translational Medicine","Metabolic Sciences"]
doi:10.7717/peerj.2824
96 downloads
371 views

Background Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment,...

["Microbiology","Infectious Diseases","Public Health","Metabolic Sciences"]
doi:10.7717/peerj.2833
92 downloads
323 views

Background White adipose tissue (WAT) is a complex, diffuse, multifunctional organ which contains adipocytes, and a large proportion of fat, but also other cell types, active in defense, regeneration and signalling functions. Studies with adipocytes often require...

["Cell Biology","Metabolic Sciences"]
doi:10.7717/peerj.2725
148 downloads
492 views

Background Previous studies have examined the role of individuals’ personal characteristics in diabetes management and used the locus of control theory to assess adherence to a diabetes management regimen. These studies have emphasized that having internal locus...

["Diabetes and Endocrinology","Nursing","Metabolic Sciences"]
doi:10.7717/peerj.2722
197 downloads
456 views

Selenium (Se) is an essential element with a small difference between physiological and toxic doses. To provide more effective and safe Se dosing regimens, as compared to dosing with ionic selenium, nanoparticle formulations have been developed. However, due to...

["Food Science and Technology","Toxicology","Pharmacology","Metabolic Sciences"]
doi:10.7717/peerj.2601
1 citation
85 downloads
353 views

C1q TNF Related Protein 3 (CTRP3) is a novel adipose tissue derived secreted factor, or adipokine, which has been linked to a number of beneficial biological effects on metabolism, inflammation, and survival signaling in a variety of tissues. However, very little...

["Cardiology","Diabetes and Endocrinology","Public Health","Metabolic Sciences"]
doi:10.7717/peerj.2573
102 downloads
466 views

Background. A “cafeteria” diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy....

["Anatomy and Physiology","Diabetes and Endocrinology","Hematology","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.2302
88 downloads
445 views

Background. Generally, males display greater strength and muscle capacity than females while performing a task. Muscle biopsy is regarded as the reference method of evaluating muscle functions; however, it is invasive and has sampling errors, and is not practical...

["Neurology","Radiology and Medical Imaging","Metabolic Sciences"]
doi:10.7717/peerj.2259
105 downloads
450 views

Few studies have assessed the association between the rs1414334 C/G polymorphism in the HTR2C gene and the development of the metabolic syndrome in patients treated with atypical antipsychotics. To provide further evidence, a cross-sectional study was conducted...

["Diabetes and Endocrinology","Epidemiology","Psychiatry and Psychology","Statistics","Metabolic Sciences"]
doi:10.7717/peerj.2163
146 downloads
596 views

Metabolomic profiling is an increasingly important method for identifying potential biomarkers in cancer cells with a view towards improved diagnosis and treatment. Nuclear magnetic resonance (NMR) provides a potentially noninvasive means to accurately characterize...

["Biophysics","Metabolic Sciences"]
doi:10.7717/peerj.2104
409 downloads
4,164 views

Background. Alcohol consumption is a lifestyle factor associated with type 2 diabetes. This relationship is reportedly different depending on the type of alcohol beverage. The purpose of this study was to examine the acute effects of traditional Japanese alcohol...

["Food Science and Technology","Toxicology","Diabetes and Endocrinology","Neurology","Metabolic Sciences"]
doi:10.7717/peerj.1853
305 downloads
695 views

Background. Leprosy reactions are acute inflammatory episodes that occur mainly in the multibacillary forms of the disease. The reactions are classified as type 1 (reverse reaction) or type 2 (erythema nodosum leprosum). Leprosy-associated oxidative stress has...

["Dermatology","Infectious Diseases","Metabolic Sciences"]
doi:10.7717/peerj.1799
4 citations
527 downloads
1,422 views

The digestive tract of mammals and other animals is colonized by trillions of metabolically-active microorganisms. Changes in the gut microbiota have been associated with obesity in both humans and laboratory animals. Dietary modifications can often modulate the...

["Bioinformatics","Food science and technology","Microbiology","Nutrition","Metabolic sciences"]
doi:10.7717/peerj.1702
4 citations
249 downloads
933 views

Background. Adipose tissue contributes to the inflammatory response through production of cytokines, recruitment of macrophages and modulation of the adiponectin system. Previous studies have identified a down-regulation of adiponectin in pathologies characterised...

["Translational Medicine","Metabolic Sciences"]
doi:10.7717/peerj.1428

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