Peer-reviewed Articles - Medicine

50 downloads
197 views

Background Zika virus (ZIKV) transmission has been reported in 67 countries/territories in the Oceania region and the Americas since 2015, prompting the World Health Organization (WHO) to declare ZIKV as a Public Health Emergency of International Concern in February...

["Mathematical Biology","Virology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3015
30 downloads
192 views

Background This study evaluates two procedures for typing of Streptococcus agalactiae (group B streptococci; GBS) isolates, using retrospective typing data from the period 2010 to 2014 with a commercial latex agglutination test (latex test) and the Lancefield precipitation...

["Microbiology","Epidemiology","Infectious Diseases","Internal Medicine","Pediatrics"]
doi:10.7717/peerj.3105
83 downloads
490 views

Zika virus is a newly emergent mosquito-borne flavivirus that has caused recent large outbreaks in the new world, leading to dramatic increases in serious disease pathology including Guillain-Barre syndrome, newborn microcephaly, and infant brain damage. Although...

["Entomology","Virology","Global Health","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3096
36 downloads
153 views

Background Dengue is a global human public health threat, causing severe morbidity and mortality. The occurrence of sequential infection by more than one serotype of dengue virus (DENV) is a major contributing factor for the induction of Dengue Hemorrhagic Fever...

["Molecular Biology","Virology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2970
63 downloads
304 views

American trypanosomiasis is a chronic and endemic disease which affects millions of people. Trypanosoma cruzi, its causative agent, has a life cycle that involves complex morphological and functional transitions, as well as a variety of environmental conditions....

["Biochemistry","Genomics","Molecular Biology","Parasitology","Infectious Diseases"]
doi:10.7717/peerj.3017
147 downloads
506 views

Rhodomyrtone, a natural antimicrobial compound, displays potent activity against many Gram-positive pathogenic bacteria, comparable to last-defence antibiotics including vancomycin and daptomycin. Our previous studies pointed towards effects of rhodomyrtone on...

["Biochemistry","Computational Biology","Microbiology","Drugs and Devices","Infectious Diseases"]
doi:10.7717/peerj.2962
114 downloads
334 views

Streptococcus pneumoniae remains the leading causative pathogen in pediatric pneumonia and bacteremia throughout the world. The invasive pneumococcal disease (IPD) is known as isolation of S. pneumoniae from a normally sterile site (e.g., blood, cerebrospinal fluid,...

["Emergency and Critical Care","Epidemiology","Infectious Diseases","Pediatrics","Public Health"]
doi:10.7717/peerj.2941
137 downloads
687 views

From early 2012, a novel clone of vancomycin resistant Enterococcus faecium (assigned the multi locus sequence type ST796) was simultaneously isolated from geographically separate hospitals in south eastern Australia and New Zealand. Here we describe the complete...

["Evolutionary Studies","Genomics","Microbiology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2916
124 downloads
402 views

Klebsiella pneumoniae is responsible for numerous infections caused in hospitals, leading to mortality and morbidity. It has been evolving as a multi-drug resistant pathogen, acquiring multiple resistances such as such as horizontal gene transfer, transposon-mediated...

["Microbiology","Molecular Biology","Drugs and Devices","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2896
61 downloads
198 views

Background Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as antigen-specific IFN- γ responses are not well characterized. Methods IFN- γ responses to the P. falciparum antigens...

["Immunology","Infectious Diseases"]
doi:10.7717/peerj.2855
64 downloads
348 views

The emergence and spread of drug-resistance during treatment of many infectious diseases continue to degrade our ability to control and mitigate infection outcomes using therapeutic measures. While the coverage and efficacy of treatment remain key factors in the...

["Mathematical Biology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2817
95 downloads
366 views

Background Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment,...

["Microbiology","Infectious Diseases","Public Health","Metabolic Sciences"]
doi:10.7717/peerj.2833
173 downloads
728 views

G1P[8] rotaviruses are responsible for the majority of human rotavirus infections worldwide. The effect of universal mass vaccination with rotavirus vaccines on circulating G1P[8] rotaviruses is still poorly understood. Therefore we analyzed the complete genomes...

["Virology","Gastroenterology and Hepatology","Infectious Diseases"]
doi:10.7717/peerj.2733
152 downloads
325 views

Melioidosis, an infection caused by the facultative intracellular pathogen Burkholderia pseudomallei, has been classified as an emerging disease with the number of patients steadily increasing at an alarming rate. B. pseudomalleipossess various virulence determinants...

["Bioinformatics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.2532
71 downloads
321 views

Tuberculosis is considered a leading cause of death worldwide. More than 95% of cases and deaths occur in low- and middle-income countries. In resource-limited countries, hospitals often lack adequate facilities to manage and isolate patients with infectious tuberculosis...

["Microbiology","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7717/peerj.2795

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