Peer-reviewed Articles - Medicine

30 downloads
441 views

The core antigen of the hepatitis C virus (HCV Ag) presents an alternative marker to HCV RNA when screening patients for HCV viremia. This study sought to evaluate the utility of HCV Ag as a marker to assess active HCV infection in individuals residing in an HCV-endemic...

["Molecular Biology","Virology","Epidemiology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4008
1 citation
147 downloads
928 views

Aim To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. Methods The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical...

["Clinical Trials","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.3654
100 downloads
572 views

The death-associated protein kinase 1 (DAPK1) can act as an oncogene or a tumor suppressor gene depending on the cellular context as well as external stimuli. Our study aims to investigate the prognostic significance of DAPK1 in liver cancer in both mRNA and protein...

["Biochemistry","Gastroenterology and Hepatology","Oncology","Translational Medicine","Histology"]
doi:10.7717/peerj.3568
137 downloads
552 views

Background As the fifth most common cancer worldwide, Hepatocellular carcinoma (HCC) is also the third most common cause of cancer-related death in China. Several lncRNAs have been demonstrated to be associated with occurrence and prognosis of HCC. However, identification...

["Bioinformatics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3575
67 downloads
434 views

Background Other studies have assessed nonadherence to proton pump inhibitors (PPIs), but none has developed a screening test for its detection. Objectives To construct and internally validate a predictive model for nonadherence to PPIs. Methods This prospective...

["Drugs and Devices","Epidemiology","Gastroenterology and Hepatology","Pharmacology","Human-Computer Interaction"]
doi:10.7717/peerj.3455
263 downloads
1,347 views

Bariatric surgery is highly successful in improving health compared to conventional dietary treatments. It has been suggested that the gut microbiota is a relevant factor in weight loss after bariatric surgery. Considering that bariatric procedures cause different...

["Genomics","Microbiology","Gastroenterology and Hepatology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3443
252 downloads
668 views

Gastric cancer is an aggressive cancer that is often diagnosed late. Early detection and treatment require a better understanding of the molecular pathology of the disease. The present study combined data on gene expression and regulatory levels (microRNA, methylation,...

["Bioinformatics","Genetics","Genomics","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3385
131 downloads
474 views

Background Several studies report aberrant expression of sine oculis homeobox (SIX) homolog family members during cancer development and progression. SIX4 participates in organ development, such as myogenesis and neurogenesis. However, the expression and clinical...

["Biochemistry","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3394
119 downloads
360 views

Helicobacter pylori (H. pylori) is one of the most common human bacterial infections with prevalence rates between 10–80% depending upon geographical location, age and socioeconomic status. H. pylori is commonly found in patients complaining of dyspepsia and is...

["Gastroenterology and Hepatology","HIV"]
doi:10.7717/peerj.3392
1 citation
254 downloads
822 views

Prebiotics are selectively fermentable dietary compounds that result in changes in the composition and/or activity of the intestinal microbiota, thus conferring benefits upon host health. In veterinary medicine, commercially available products containing prebiotics...

["Bioinformatics","Microbiology","Veterinary Medicine","Gastroenterology and Hepatology","Nutrition"]
doi:10.7717/peerj.3184
1 citation
262 downloads
652 views

Background The promising postsurgical weight loss and remission of type 2 diabetes (T2D) from bariatric surgery can be attributed to modified eating physiology after surgical procedures. We sought to investigate the changes in the parameters of consumption behaviors...

["Diabetes and Endocrinology","Gastroenterology and Hepatology","Psychiatry and Psychology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3090
2 citations
130 downloads
417 views

Background and Aim The infection of Helicobacter pylori (H. pylori) is acquired in childhood and the prevalence vary greatly in different countries and regions. The study aimed to investigate the characteristics of H. pylori infection among children with gastrointestinal...

["Gastroenterology and Hepatology","Pediatrics"]
doi:10.7717/peerj.2937
3 citations
459 downloads
1,465 views

Background Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously...

["Food Science and Technology","Microbiology","Gastroenterology and Hepatology","Nutrition","Pediatrics"]
doi:10.7717/peerj.2876
146 downloads
566 views

Background Liver disease has become an important cause of morbidity and mortality even in those HIV-infected individuals who are devoid of hepatitis virus co-infection. The aim of this study was to evaluate the degree of hepatic fibrosis and the role of associated...

["Gastroenterology and Hepatology","HIV","Public Health"]
doi:10.7717/peerj.2867
2 citations
251 downloads
1,038 views

G1P[8] rotaviruses are responsible for the majority of human rotavirus infections worldwide. The effect of universal mass vaccination with rotavirus vaccines on circulating G1P[8] rotaviruses is still poorly understood. Therefore we analyzed the complete genomes...

["Virology","Gastroenterology and Hepatology","Infectious Diseases"]
doi:10.7717/peerj.2733

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