Peer-reviewed Articles - Medicine

49 downloads
351 views

Background Type II diabetes is a chronic health condition which is associated with skin conditions including chronic foot ulcers and an increased incidence of skin infections. The skin microbiome is thought to play important roles in skin defence and immune functioning....

["Microbiology","Molecular Biology","Diabetes and Endocrinology"]
doi:10.7717/peerj.3543
27 downloads
196 views

Background The association of type 2 diabetes mellitus (T2DM) with the KCNJ11, CDKAL1, SLC30A8, CDKN2B, and FTO genes in the Russian population has not been well studied. In this study, we analysed the population frequencies of polymorphic markers of these genes....

["Genetics","Diabetes and Endocrinology"]
doi:10.7717/peerj.3414
42 downloads
227 views

MicroRNAs are small non-coding RNAs, which negatively regulate the expression of target genes. They have emerged as important modulators in beta cell compensation upon increased metabolic demand, failure of which leads to reduced insulin secretion and type 2 diabetes....

["Molecular Biology","Diabetes and Endocrinology"]
doi:10.7717/peerj.3503
102 downloads
295 views

Aim To evaluate the effects of sodium-glucose co-transporter 2 (SGLT2) inhibition on renal function and albuminuria in patients with type 2 diabetes. Methods We conducted systematic searches of PubMed, Embase and Cochrane Central Register of Controlled Trials up...

["Diabetes and Endocrinology","Evidence Based Medicine","Nephrology"]
doi:10.7717/peerj.3405
1 citation
47 downloads
262 views

Background Pituitary adenoma is one of the most common intracranial neoplasms, and its primary treatment is endoscopic endonasal transsphenoidal tumorectomy. Postoperative hypokalemia in these patients is a common complication, and is associated with morbidity...

["Diabetes and Endocrinology","Epidemiology","Oncology"]
doi:10.7717/peerj.3337
126 downloads
445 views

Stellaria dichotoma L. is widely distributed in Ningxia and surrounding areas in northwestern China. Its root, Radix Stellariae (RS), has been used in herbal formulae for treating asthenic-fever, infection, malaria, dyspepsia in children and several other symptoms....

["Molecular Biology","Diabetes and Endocrinology","Global Health","Pharmacology","Metabolic Sciences"]
doi:10.7717/peerj.3305
56 downloads
357 views

Historically, Chinese herbal medicines have been widely used in the treatment of hyperglycemia, but the mechanisms underlying their effectiveness remain largely unknown. Here, we screened a compound library primarily comprised of natural compounds extracted from...

["Cell Biology","Diabetes and Endocrinology","Drugs and Devices"]
doi:10.7717/peerj.3283
102 downloads
467 views

Background Obesity has become a worldwide burden to public health in recent decades. Given that obesity is caused by an imbalance between caloric intake and expenditure, and that dietary fat is the most important energy source of all macronutrients (by providing...

["Biochemistry","Food Science and Technology","Diabetes and Endocrinology","Nutrition"]
doi:10.7717/peerj.3279
64 downloads
353 views

Background Individuals with type 2 diabetes are at an increased risk of cardiovascular disease. Alterations in circulating lipid levels, total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TG) are heritable...

["Bioinformatics","Genomics","Diabetes and Endocrinology","Translational Medicine","Metabolic Sciences"]
doi:10.7717/peerj.3187
42 downloads
338 views

Background Reduction of readmissions after discharge represents an important challenge for many hospitals and has attracted the interest of many researchers in the past few years. Most of the studies in this field focus on building cross-sectional predictive models...

["Diabetes and Endocrinology","Public Health","Computational Science"]
doi:10.7717/peerj.3230
184 downloads
550 views

Background & Aims Metformin is currently the most widely used first-line hypoglycemic agent for diabetes mellitus. Besides glucose-lowering action, there is increasingly interest in the potential anti-inflammatory action of this drug. In the present study, we investigated...

["Diabetes and Endocrinology","Pharmacology"]
doi:10.7717/peerj.3155
1 citation
202 downloads
460 views

Background The promising postsurgical weight loss and remission of type 2 diabetes (T2D) from bariatric surgery can be attributed to modified eating physiology after surgical procedures. We sought to investigate the changes in the parameters of consumption behaviors...

["Diabetes and Endocrinology","Gastroenterology and Hepatology","Psychiatry and Psychology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3090
146 downloads
503 views

Background Nowadays, the number of obese people in the world has reached alarming proportions. During the expansion of adipose tissue, a number of functions such as activation and release of cytokines and hormones may be affected. This leads the body to a pro-inflammatory...

["Diabetes and Endocrinology","Nutrition"]
doi:10.7717/peerj.2967
117 downloads
584 views

Background Hyperglycemia is a known predictor of negative outcomes in stroke. Several glycemic measures, including admission random glucose, fasting glucose, and glycated hemoglobin (HbA1c), have been associated with bad neurological outcomes in acute ischemic...

["Diabetes and Endocrinology","Neurology"]
doi:10.7717/peerj.2948
201 downloads
498 views

Background Psychological disorders are common in diabetes mellitus (DM) patients, and the aim of this study was to estimate the prevalence of psychological distress and to determine the influence factors associated with psychological distress among DM patients...

["Diabetes and Endocrinology","Epidemiology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.2869

Top subject areas - Articles

Top subject areas - People

View all subject areas