Peer-reviewed Articles - Medicine

1 citation
148 downloads
569 views

Background Interleukin (IL)-17 produced by mainly T helper 17 (Th17) cells may play an important destructive role in chronic periodontitis (CP). Thus, anti-inflammatory cytokines, such as IL-35, might have a beneficial effect in periodontitis by inhibiting differentiation...

["Dentistry","Immunology"]
doi:10.7717/peerj.2999
198 downloads
636 views

Background Dental anxiety is a widespread problem in many populations. This problem can be a barrier to dental care and may lead to poor oral health. Dental anxiety may be related to psychological status. Aims The aim of the present study was to assess the levels...

["Dentistry","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.2978
170 downloads
562 views

Background Little is known about the differences of rotary multiple file endodontic therapy and single-file reciprocating endodontic treatment under routine care conditions in dental practice. This multicenter study was performed to compare the outcome of multiple-file...

["Dentistry"]
doi:10.7717/peerj.2765
114 downloads
481 views

Background A carbon dioxide (CO2) laser has been used to morphologically and chemically modify the dental enamel surface as well as to make it more resistant to demineralization. Despite a variety of experiments demonstrating the inhibitory effect of a CO2 laser...

["Biochemistry","Dentistry"]
doi:10.7717/peerj.2458
254 downloads
519 views

Background Termination of fixed orthodontic treatment is associated with bracket debonding and residual adhesive removal. These procedures increase enamel roughness to a degree that should depend on the tool used. Enamel roughening may be associated with bacterial...

["Dentistry","Radiology and Medical Imaging"]
doi:10.7717/peerj.2558
1 citation
337 downloads
988 views

Background The composition of the salivary microbiota has been reported to differentiate between patients with periodontitis, dental caries and orally healthy individuals. To identify characteristics of diseased and healthy saliva we thus wanted to compare saliva...

["Microbiology","Dentistry","Immunology"]
doi:10.7717/peerj.2433
223 downloads
908 views

Background Periodontitis is one of the most common oral diseases associated with the host’s immune response against periodontopathogenic infection. Failure to accurately diagnose the stage of periodontitis has limited the ability to predict disease status. Therefore,...

["Molecular Biology","Dentistry"]
doi:10.7717/peerj.2327
144 downloads
492 views

Background. Tooth loss is an easily identifiable outcome that summarizes a complex suite of factors in an individual’s history of dental disease and its treatment by dental services over a lifetime. Assessment of overall tooth loss data is essential for epidemiologically...

["Dentistry","Public Health"]
doi:10.7717/peerj.2015
1 citation
307 downloads
1,029 views

Background. Little is known about the clinical impact of new root canal preparation systems in general dental practice under routine care conditions. Therefore, we compared hand instrumentation (H) with Reciproc (R) (VDW, Munich, Germany) preparation. The outcomes...

["Dentistry","Public Health"]
doi:10.7717/peerj.2182
1 citation
365 downloads
1,055 views

Monolaurin (also known as glycerol monolaurate) is a natural compound found in coconut oil and is known for its protective biological activities as an antimicrobial agent. The nature of oral candidiasis and the increased antifungal resistance demand the search...

["Cell Biology","Microbiology","Dentistry"]
doi:10.7717/peerj.2148
2 citations
217 downloads
1,077 views

Background. A loss of mucosal tolerance to the resident microbiome has been postulated in the aetiopathogenesis of spondyloarthritis, thus the purpose of these studies was to investigate microbial communities that colonise the oral cavity of patients with axial...

["Microbiology","Dentistry","Rheumatology"]
doi:10.7717/peerj.2095
935 downloads
1,084 views

Background. The inconsistent prevalence of fluorosis for a given level of fluoride in drinking water suggests developmental defects of enamel (DDEs) other than fluorosis were being misdiagnosed as fluorosis. The imprecise definition and subjective perception of...

["Dentistry","Epidemiology"]
doi:10.7717/peerj.1745
1 citation
259 downloads
1,306 views

Background. Mouse dental mesenchymal cells (mDMCs) from tooth germs of cap or later stages are frequently used in the context of developmental biology or whole-tooth regeneration due to their odontogenic potential. In vitro-expanded mDMCs serve as an alternative...

["Bioinformatics","Cell Biology","Developmental Biology","Dentistry"]
doi:10.7717/peerj.1684
1 citation
138 downloads
776 views

Objectives. The objective of this study is to compare the impact of early and late reconstruction of complete unilateral cleft lip and palate on the growth and development of the front of the dentoalveolar arch. Methods. This study was carried out in the years...

["Dentistry","Otorhinolaryngology","Pediatrics","Surgery and surgical specialties"]
doi:10.7717/peerj.1620
536 downloads
1,151 views

It is generally accepted that the effect of orthodontic tooth movement on the dental pulp in adolescents is reversible and that it has no long-lasting effect on pulpal physiology. However, it is not clear yet if the same conclusion is also valid for adult subjects....

["Zoology","Dentistry","Histology"]
doi:10.7717/peerj.1625

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