Peer-reviewed Articles - Medicine

29 downloads
159 views

Objective Circulating endothelial progenitor cells (EPCs) correlate negatively with obesity. Previous studies have shown that exercise significantly restores circulating EPC levels in obese people; however, the underlying mechanisms have not been elucidated. Recently,...

["Neuroscience","Cardiology","Clinical Trials","Nutrition"]
doi:10.7717/peerj.3669
38 downloads
686 views

Aim To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. Methods The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical...

["Clinical Trials","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.3654
37 downloads
228 views

Oxidative damage is a major cause of lung diseases, including pulmonary fibrosis. Laminarin is a kind of polysaccharide extracted from brown algae and plays vital roles in various biological processes. However, the functions and mechanisms of laminarin in pulmonary...

["Molecular Biology","Clinical Trials","Internal Medicine","Otorhinolaryngology"]
doi:10.7717/peerj.3642
73 downloads
299 views

Background Deliberate hypotension is one way to achieve a bloodless surgical field in endoscopic sinus surgery (ESS). We compared two anaesthesia regimens to induce deliberate hypotension and attempted to determine the most efficient one. Methods Fifty-nine patients...

["Anaesthesiology and Pain Management","Clinical Trials","Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3370
1 citation
129 downloads
571 views

Background Exergames are a new form of rehabilitation that combine the characteristics of physical exercise and the benefits of non-immersive virtual reality (VR). Effects of this novel therapy in women fibromyalgia are still unknown. The objective was to evaluate...

["Clinical Trials","Kinesiology","Women\u2019s Health"]
doi:10.7717/peerj.3211
254 downloads
1,055 views

Drug repositioning (i.e., drug repurposing) is the process of discovering new uses for marketed drugs. Historically, such discoveries were serendipitous. However, the rapid growth in electronic clinical data and text mining tools makes it feasible to systematically...

["Bioinformatics","Clinical Trials","Drugs and Devices","Oncology","Statistics"]
doi:10.7717/peerj.3154
1 citation
593 downloads
1,367 views

This study investigated whether a yoga exercise intervention influenced the sustained attention and discrimination function in children with ADHD. Forty-nine participants (mean age = 10.50 years) were assigned to either a yoga exercise or a control group. Participants...

["Clinical Trials","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.2883
7 citations
568 downloads
2,072 views

Context Necrotizing enterocolitis (NEC) is the most frequent gastrointestinal emergency in neonates. The microbiome of the preterm gut may regulate the integrity of the intestinal mucosa. Probiotics may positively contribute to mucosal integrity, potentially reducing...

["Clinical Trials","Drugs and Devices","Evidence Based Medicine","Pediatrics"]
doi:10.7717/peerj.2429
3 citations
151 downloads
849 views

Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. The methodologies for generating tolAPC vary greatly...

["Clinical Trials","Immunology","Translational Medicine","Computational Science"]
doi:10.7717/peerj.2300
2 citations
760 downloads
4,634 views

Objective. Probiotics have been reported to support healthy digestive and immune function, aid in protein absorption, and decrease inflammation. Further, a trend to increase vertical jump power has been observed following co-administration of protein and probiotics...

["Clinical Trials","Evidence Based Medicine","Nutrition"]
doi:10.7717/peerj.2276
5 citations
466 downloads
3,031 views

Background. Imaging biomarkers hold tremendous promise for precision medicine clinical applications. Development of such biomarkers relies heavily on image post-processing tools for automated image quantitation. Their deployment in the context of clinical research...

["Bioinformatics","Clinical Trials","Oncology","Radiology and Medical Imaging"]
doi:10.7717/peerj.2057
2 citations
252 downloads
1,195 views

The objective of the study was to examine the feasibility and benefits of a group resistance training exercise programme for improving muscle function in institutionalised older adults. A feasibility and acceptability study was designed for a residential aged care...

["Clinical Trials","Geriatrics","Kinesiology","Public Health"]
doi:10.7717/peerj.2018
4 citations
526 downloads
1,800 views

Background. Due to inadequate UV exposure, intake of small quantities of vitamin D is recommended to prevent musculoskeletal disease. Both basic science and observational literature strongly suggest that higher doses may benefit specific populations and have non-musculoskeletal...

["Clinical Trials","Diabetes and Endocrinology","Evidence Based Medicine","Nutrition","Pediatrics"]
doi:10.7717/peerj.1701
2 citations
250 downloads
1,075 views

Over the past 60 years, the Mycobacterium bovis bacille Calmette–Guérin (BCG) has been used worldwide to prevent tuberculosis (TB). However, BCG has shown a very variable efficacy in different trials, offering a wide range of protection in adults against pulmonary...

["Mathematical Biology","Clinical Trials","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.1513
5 citations
481 downloads
1,833 views

Background. Pharmacogenomic testing has the potential to improve the safety and efficacy of pharmacotherapy, but clinical application of pharmacogenetic knowledge has remained uncommon. Clinical Decision Support (CDS) systems could help overcome some of the barriers...

["Clinical trials","Drugs and devices","Health policy","Science policy","Human-Computer interaction"]
doi:10.7717/peerj.1671

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