Peer-reviewed Articles - Medicine

45 downloads
227 views

Background Deliberate hypotension is one way to achieve a bloodless surgical field in endoscopic sinus surgery (ESS). We compared two anaesthesia regimens to induce deliberate hypotension and attempted to determine the most efficient one. Methods Fifty-nine patients...

["Anaesthesiology and Pain Management","Clinical Trials","Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3370
1 citation
111 downloads
511 views

Background Exergames are a new form of rehabilitation that combine the characteristics of physical exercise and the benefits of non-immersive virtual reality (VR). Effects of this novel therapy in women fibromyalgia are still unknown. The objective was to evaluate...

["Clinical Trials","Kinesiology","Women\u2019s Health"]
doi:10.7717/peerj.3211
189 downloads
923 views

Drug repositioning (i.e., drug repurposing) is the process of discovering new uses for marketed drugs. Historically, such discoveries were serendipitous. However, the rapid growth in electronic clinical data and text mining tools makes it feasible to systematically...

["Bioinformatics","Clinical Trials","Drugs and Devices","Oncology","Statistics"]
doi:10.7717/peerj.3154
1 citation
519 downloads
1,219 views

This study investigated whether a yoga exercise intervention influenced the sustained attention and discrimination function in children with ADHD. Forty-nine participants (mean age = 10.50 years) were assigned to either a yoga exercise or a control group. Participants...

["Clinical Trials","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.2883
4 citations
520 downloads
1,827 views

Context Necrotizing enterocolitis (NEC) is the most frequent gastrointestinal emergency in neonates. The microbiome of the preterm gut may regulate the integrity of the intestinal mucosa. Probiotics may positively contribute to mucosal integrity, potentially reducing...

["Clinical Trials","Drugs and Devices","Evidence Based Medicine","Pediatrics"]
doi:10.7717/peerj.2429
2 citations
140 downloads
787 views

Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. The methodologies for generating tolAPC vary greatly...

["Clinical Trials","Immunology","Translational Medicine","Computational Science"]
doi:10.7717/peerj.2300
2 citations
707 downloads
4,203 views

Objective. Probiotics have been reported to support healthy digestive and immune function, aid in protein absorption, and decrease inflammation. Further, a trend to increase vertical jump power has been observed following co-administration of protein and probiotics...

["Clinical Trials","Evidence Based Medicine","Nutrition"]
doi:10.7717/peerj.2276
4 citations
416 downloads
2,715 views

Background. Imaging biomarkers hold tremendous promise for precision medicine clinical applications. Development of such biomarkers relies heavily on image post-processing tools for automated image quantitation. Their deployment in the context of clinical research...

["Bioinformatics","Clinical Trials","Oncology","Radiology and Medical Imaging"]
doi:10.7717/peerj.2057
2 citations
223 downloads
1,138 views

The objective of the study was to examine the feasibility and benefits of a group resistance training exercise programme for improving muscle function in institutionalised older adults. A feasibility and acceptability study was designed for a residential aged care...

["Clinical Trials","Geriatrics","Kinesiology","Public Health"]
doi:10.7717/peerj.2018
4 citations
473 downloads
1,725 views

Background. Due to inadequate UV exposure, intake of small quantities of vitamin D is recommended to prevent musculoskeletal disease. Both basic science and observational literature strongly suggest that higher doses may benefit specific populations and have non-musculoskeletal...

["Clinical Trials","Diabetes and Endocrinology","Evidence Based Medicine","Nutrition","Pediatrics"]
doi:10.7717/peerj.1701
2 citations
224 downloads
1,029 views

Over the past 60 years, the Mycobacterium bovis bacille Calmette–Guérin (BCG) has been used worldwide to prevent tuberculosis (TB). However, BCG has shown a very variable efficacy in different trials, offering a wide range of protection in adults against pulmonary...

["Mathematical Biology","Clinical Trials","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.1513
5 citations
446 downloads
1,793 views

Background. Pharmacogenomic testing has the potential to improve the safety and efficacy of pharmacotherapy, but clinical application of pharmacogenetic knowledge has remained uncommon. Clinical Decision Support (CDS) systems could help overcome some of the barriers...

["Clinical trials","Drugs and devices","Health policy","Science policy","Human-Computer interaction"]
doi:10.7717/peerj.1671
3 citations
283 downloads
2,208 views

The validity of studies that assess the effectiveness of an intervention (EoI) depends on variables such as the type of study design, the quality of their methodology, and the participants enrolled. Five leading veterinary journals and 5 leading human medical journals...

["Veterinary medicine","Clinical trials","Evidence based medicine","Translational medicine"]
doi:10.7717/peerj.1649
138 downloads
772 views

The effects of isoflurane on the determinants of blood flow during Coronary Artery Bypass Graft (CABG) surgery are not completely understood. This study characterized the influence of isoflurane on the diastolic Pressure-Flow (P-F) relationship and Critical Occlusion...

["Anaesthesiology and pain management","Cardiology","Clinical trials","Emergency and critical care","Surgery and surgical specialties"]
doi:10.7717/peerj.1619
14 citations
1,610 downloads
9,450 views

Background. Mobile health and digital medicine technologies are becoming increasingly used by individuals with common, chronic diseases to monitor their health. Numerous devices, sensors, and apps are available to patients and consumers–some of which have been...

["Clinical trials","Health policy","Translational medicine"]
doi:10.7717/peerj.1554

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