Peer-reviewed Articles - Medicine

108 downloads
296 views

Background Cardiac stem cells (CSCs) play a vital role in cardiac homeostasis. A decrease in the efficiency of cardiac stem cells is speculated in various cardiac abnormalities. The maintenance of a healthy stem cell population is essential for the prevention of...

["Cell Biology","Cardiology"]
doi:10.7717/peerj.3882
69 downloads
318 views

Objective The present study aimed to assess the effects of exercise with dietary restriction on cardiac autonomic activity, arterial stiffness, and cardiovascular biomarkers in obese individuals. Methods Seventeen obese adults completed an 8-week exercise and dietary...

["Developmental Biology","Neuroscience","Cardiology","Clinical Trials"]
doi:10.7717/peerj.3900
47 downloads
205 views

Background Individuals with type 2 diabetes (T2D) are at an increased risk of coronary heart disease (CHD). Diabetic complications have recently been associated with a measure of glucose metabolism known as the hemoglobin glycation index (HGI). Currently there...

["Cardiology","Diabetes and Endocrinology"]
doi:10.7717/peerj.3875
161 downloads
1,876 views

Objective Extracorporeal life support (ECLS) is a life-saving procedure used in the treatment of severe cardiogenic shock. Within this retrospective single centre study, we examined our experience in this critically ill patient cohort to assess outcomes and clinical...

["Cardiology","Clinical Trials","Emergency and Critical Care","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3813
54 downloads
270 views

Background Hypertension and dyssomnia are increasing significantly in Mongolians, and the related factors of ethnic differences in hypertension and dyssomnia between Mongolians and Han Chinese are unclear. This study examined the relationship of morning surge in...

["Cardiology","Global Health","Public Health"]
doi:10.7717/peerj.3758
111 downloads
641 views

Background New-onset atrial fibrillation (AF) is the most common arrhythmia in critically ill patients. Although evidence base and expert consensus opinion for management have been summarised in several international guidelines, no specific considerations for critically...

["Anaesthesiology and Pain Management","Cardiology","Emergency and Critical Care"]
doi:10.7717/peerj.3716
1 citation
155 downloads
571 views

Objective Circulating endothelial progenitor cells (EPCs) correlate negatively with obesity. Previous studies have shown that exercise significantly restores circulating EPC levels in obese people; however, the underlying mechanisms have not been elucidated. Recently,...

["Neuroscience","Cardiology","Clinical Trials","Nutrition"]
doi:10.7717/peerj.3669
56 downloads
291 views

Background Hypoxia-inducible factor (HIF)-1 is involved in the regulation of hypoxic preconditioning in cardiomyocytes. Under hypoxic conditions, HIF-1α accumulates and is translocated to the nucleus, where it forms an active complex with HIF-1β and activates transcription...

["Cell Biology","Anaesthesiology and Pain Management","Cardiology"]
doi:10.7717/peerj.3662
124 downloads
627 views

Background Psychological factors have been suggested to have an influence in Atrial Fibrillation (AF) onset, progression, severity and outcomes, but their role is unclear and mainly focused on anxiety and depression. Methods A systematic electronic search had been...

["Cardiology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.3537
1 citation
226 downloads
710 views

Introduction Our study aims at identifying and quantifying the relationship between the cold and heat exposure and the risk of cardiovascular mortality through a systematic review and meta-analysis. Material and Methods A systematic review and meta-analysis were...

["Cardiology","Public Health"]
doi:10.7717/peerj.3574
105 downloads
582 views

Background c-Kit is a receptor tyrosine kinase present in multiple cell types, including vascular smooth muscle cells (SMC). However, little is known about how c-Kit influences SMC biology and vascular pathogenesis. Methods High-throughput microarray assays and...

["Molecular Biology","Cardiology","Pharmacology"]
doi:10.7717/peerj.3418
234 downloads
593 views

Background The kidney is always subjected to high metabolic demand. The aim of this study was to characterize metabolic profiles of a rat model of chronic kidney disease (CKD) with cardiorenal syndrome (CRS) induced by prolonged hypertension. Methods We used inbred...

["Molecular Biology","Cardiology","Nephrology"]
doi:10.7717/peerj.3352
110 downloads
415 views

Our previous study demonstrated that tentacle extract (TE) from the jellyfish Cyanea capillata (C. capillata) could cause a weak relaxation response mediated by nitric oxide (NO) using isolated aorta rings. However, the intracellular mechanisms of TE-induced vasodilation...

["Cell Biology","Marine Biology","Cardiology"]
doi:10.7717/peerj.3172
4 citations
172 downloads
504 views

Background Sevoflurane postconditioning (S-post) has similar cardioprotective effects as ischemic preconditioning. However, the underlying mechanism of S-post has not been fully elucidated. Janus kinase signaling transduction/transcription activator (JAK2–STAT3)...

["Anesthesiology and Pain Management","Cardiology","Translational Medicine"]
doi:10.7717/peerj.3196
104 downloads
480 views

Background Resveratrol is a cardioprotective agent with known antiarrhythmic effects that has recently been shown to inhibit phosphodiesterase (PDE) enzyme activity. Thus, it is possible that resveratrol increases the inotropic effect of sympathomimetic agents,...

["Cardiology","Drugs and Devices","Pharmacology"]
doi:10.7717/peerj.3113

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