Peer-reviewed Articles - General

48 downloads
281 views

The Ramachandran plot is important to structural biology as it describes a peptide backbone in the context of its dominant degrees of freedom—the backbone dihedral angles φ and ψ (Ramachandran, Ramakrishnan & Sasisekharan, 1963). Since its introduction, the Ramachandran...

["Computational Biology","Mathematical Biology","Computational Science"]
doi:10.7717/peerj.3327
163 downloads
747 views

Background The goals of this study were (1) to present the set of data evaluating running biomechanics (kinematics and kinetics), including data on running habits, demographics, and levels of muscle strength and flexibility made available at Figshare (DOI: 10.6084/m9.figshare.4543435);...

["Bioengineering","Neuroscience","Kinesiology","Computational Science"]
doi:10.7717/peerj.3298
58 downloads
607 views

Obstructive sleep apnea syndrome (OSAS) is a common clinical condition. The way that OSAS risk factors associate and converge is not a random process. As such, defining OSAS phenotypes fosters personalized patient management and population screening. In this paper,...

["Bioinformatics","Computational Biology","Health Policy","Respiratory Medicine","Computational Science"]
doi:10.7717/peerj.3289
27 downloads
262 views

Background Reduction of readmissions after discharge represents an important challenge for many hospitals and has attracted the interest of many researchers in the past few years. Most of the studies in this field focus on building cross-sectional predictive models...

["Diabetes and Endocrinology","Public Health","Computational Science"]
doi:10.7717/peerj.3230
85 downloads
424 views

Individuals vary in their tendency to bind signals from multiple senses. For the same set of sights and sounds, one individual may frequently integrate multisensory signals and experience a unified percept, whereas another individual may rarely bind them and often...

["Neuroscience","Psychiatry and Psychology","Computational Science"]
doi:10.7717/peerj.3143
116 downloads
479 views

Identification of arthropods important in disease transmission is a crucial, yet difficult, task that can demand considerable training and experience. An important case in point is that of the 150+ species of Triatominae, vectors of Trypanosoma cruzi, causative...

["Entomology","Computational Science"]
doi:10.7717/peerj.3040
73 downloads
860 views

Background Intervention programs to promote physical activity in older adults, either in group or home settings, have shown equivalent health outcomes but different results when considering adherence. Group-based interventions seem to achieve higher participation...

["Geriatrics","Kinesiology","Public Health","Human-Computer Interaction","Computational Science"]
doi:10.7717/peerj.3150
128 downloads
831 views

Most reconstruction methods for genomes of ancient origin that are used today require a closely related reference. In order to identify genomic rearrangements or the deletion of whole genes, de novo assembly has to be used. However, because of inherent problems...

["Bioinformatics","Paleontology","Computational Science"]
doi:10.7717/peerj.3126
64 downloads
530 views

Gene regulation modulates RNA expression via transcription factors. Post-transcriptional gene regulation in turn influences the amount of protein product through, for example, microRNAs (miRNAs). Experimental establishment of miRNAs and their effects is complicated...

["Bioinformatics","Computational Biology","Computational Science"]
doi:10.7717/peerj.3131
72 downloads
364 views

The number of protein structures in the PDB database has been increasing more than 15-fold since 1999. The creation of computational models predicting enzymatic function is of major importance since such models provide the means to better understand the behavior...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.3095
400 downloads
3,774 views

The abundant dinosaurian tracksites of the Lower Cretaceous (Valanginian–Barremian) Broome Sandstone of the Dampier Peninsula, Western Australia, form an important part of the West Kimberley National Heritage Place. Previous attempts to document these tracksites...

["Paleontology","Computational Science"]
doi:10.7717/peerj.3013
144 downloads
743 views

Hydrolysis of ATP by Na+/K+-ATPase, a P-Type ATPase, catalyzing active Na+ and K+ transport through cellular membranes leads transiently to a phosphorylation of its catalytical α-subunit. Surprisingly, three-dimensional molecular structure analysis of P-type ATPases...

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Computational Science"]
doi:10.7717/peerj.3087
83 downloads
349 views

Most of the previous studies on Weis-Fogh clap-fling mechanism have focused on the vortex structures and velocity fields. Detailed pressure distribution results are provided for the first time in this study to reveal the differences between the full and the partial...

["Biophysics","Computational Biology","Entomology","Mathematical Biology","Computational Science"]
doi:10.7717/peerj.3002
110 downloads
399 views

Background In the era of semantic web, life science ontologies play an important role in tasks such as annotating biological objects, linking relevant data pieces, and verifying data consistency. Understanding ontology structures and overlapping ontologies is essential...

["Bioinformatics","Computational Science"]
doi:10.7717/peerj.2990
276 downloads
1,194 views

Background De novo transcriptome assembly of short reads is now a common step in expression analysis of organisms lacking a reference genome sequence. Several software packages are available to perform this task. Even if their results are of good quality it is...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.2988

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