Peer-reviewed Articles - General

24 downloads
189 views

Assay for Transposase Accessible Chromatin (ATAC-seq) is an open chromatin profiling assay that is adapted to interrogate chromatin accessibility from small cell numbers. ATAC-seq surmounted a major technical barrier and enabled epigenome profiling of clinical...

["Bioinformatics","Computational Biology","Genomics","Human-Computer Interaction","Computational Science"]
doi:10.7717/peerj.4040
25 downloads
471 views

In this paper, we have presented a microwave scattering analysis from multiple human head models. This study incorporates different levels of detail in the human head models and its effect on microwave scattering phenomenon. Two levels of detail are taken into...

["Bioengineering","Biophysics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.4061
25 downloads
151 views

Evaluation of depth of anaesthesia (DoA) is critical in clinical surgery. Indices derived from electroencephalogram (EEG) are currently widely used to quantify DoA. However, there are known to be inaccurate under certain conditions; therefore, experienced anaesthesiologists...

["Anaesthesiology and Pain Management","Statistics","Computational Science"]
doi:10.7717/peerj.4067
69 downloads
400 views

Brain activity during sleep is fairly ubiquitous and the best studied possible function is a role in memory consolidation, including motor memory. One suggested mechanism of how neural activity effects these benefits is through reactivation of neurons in patterns...

["Animal Behavior","Neuroscience","Computational Science"]
doi:10.7717/peerj.4052
29 downloads
251 views

Robotic labs, in which experiments are carried out entirely by robots, have the potential to provide a reproducible and transparent foundation for performing basic biomedical laboratory experiments. In this article, we investigate whether these labs could be applicable...

["Biochemistry","Science Policy","Computational Science"]
doi:10.7717/peerj.3997
45 downloads
233 views

Hands motor imagery (MI) has been reported to alter synchronization patterns amongst neurons, yielding variations in the mu and beta bands’ power spectral density (PSD) of the electroencephalography (EEG) signal. These alterations have been used in the field of...

["Neuroscience","Neurology","Human-Computer Interaction","Computational Science"]
doi:10.7717/peerj.3983
115 downloads
605 views

RNA-Seq is a recent and efficient technique that uses the capabilities of next-generation sequencing technology for characterizing and quantifying transcriptomes. One important task using gene-expression data is to identify a small subset of genes that can be used...

["Bioinformatics","Computational Biology","Statistics","Medical Genetics","Computational Science"]
doi:10.7717/peerj.3890
63 downloads
310 views

Objectives Practitioners of mindfulness are reported to have greater cognitive control especially in conflict monitoring, response inhibition and sustained attention. However, due to the various existing methods in each mindfulness practices and also, the high...

["Neuroscience","Respiratory Medicine","Computational Science"]
doi:10.7717/peerj.3857
176 downloads
822 views

Segmentation of histopathology sections is a necessary preprocessing step for digital pathology. Due to the large variability of biological tissue, machine learning techniques have shown superior performance over conventional image processing methods. Here we present...

["Bioengineering","Oncology","Radiology and Medical Imaging","Histology","Computational Science"]
doi:10.7717/peerj.3874
163 downloads
1,116 views

Taxonomic markers such as the 16S ribosomal RNA gene are widely used in microbial community analysis. A common first step in marker-gene analysis is grouping genes into clusters to reduce data sets to a more manageable size and potentially mitigate the effects...

["Bioinformatics","Ecology","Microbiology","Computational Science"]
doi:10.7717/peerj.3812
97 downloads
522 views

Life science ontologies play an important role in Semantic Web. Given the diversity in fish species and the associated wealth of information, it is imperative to develop an ontology capable of linking and integrating this information in an automated fashion. As...

["Aquaculture, Fisheries and Fish Science","Bioinformatics","Computational Science"]
doi:10.7717/peerj.3811
66 downloads
370 views

A new method for automatic optic disc localization and segmentation is presented. The localization procedure combines vascular and brightness information to provide the best estimate of the optic disc center which is the starting point for the segmentation algorithm....

["Ophthalmology","Radiology and Medical Imaging","Human\u2013Computer Interaction","Computational Science"]
doi:10.7717/peerj.3763
83 downloads
383 views

A key step in the transformation of raw sequencing reads into biological insights is the trimming of adapter sequences and low-quality bases. Read trimming has been shown to increase the quality and reliability while decreasing the computational requirements of...

["Bioinformatics","Genomics","Computational Science"]
doi:10.7717/peerj.3720
170 downloads
721 views

Background In light of the rapid decrease in fossils fuel reserves and an increasing demand for energy, novel methods are required to explore alternative biofuel production processes to alleviate these pressures. A wide variety of molecules which can either be...

["Bioinformatics","Computational Science"]
doi:10.7717/peerj.3497
94 downloads
870 views

Gene Co-expression Network Analysis (GCNA) is a popular approach to analyze a collection of gene expression profiles. GCNA yields an assignment of genes to gene co-expression modules, a list of gene sets statistically over-represented in these modules, and a gene-to-gene...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.3678

Top subject areas - Articles

Top subject areas - People

View all subject areas