Peer-reviewed Articles - General

43 downloads
265 views

Identification of arthropods important in disease transmission is a crucial, yet difficult, task that can demand considerable training and experience. An important case in point is that of the 150+ species of Triatominae, vectors of Trypanosoma cruzi, causative...

["Entomology","Computational Science"]
doi:10.7717/peerj.3040
38 downloads
729 views

Background Intervention programs to promote physical activity in older adults, either in group or home settings, have shown equivalent health outcomes but different results when considering adherence. Group-based interventions seem to achieve higher participation...

["Geriatrics","Kinesiology","Public Health","Human-Computer Interaction","Computational Science"]
doi:10.7717/peerj.3150
95 downloads
693 views

Most reconstruction methods for genomes of ancient origin that are used today require a closely related reference. In order to identify genomic rearrangements or the deletion of whole genes, de novo assembly has to be used. However, because of inherent problems...

["Bioinformatics","Paleontology","Computational Science"]
doi:10.7717/peerj.3126
54 downloads
472 views

Gene regulation modulates RNA expression via transcription factors. Post-transcriptional gene regulation in turn influences the amount of protein product through, for example, microRNAs (miRNAs). Experimental establishment of miRNAs and their effects is complicated...

["Bioinformatics","Computational Biology","Computational Science"]
doi:10.7717/peerj.3131
54 downloads
302 views

The number of protein structures in the PDB database has been increasing more than 15-fold since 1999. The creation of computational models predicting enzymatic function is of major importance since such models provide the means to better understand the behavior...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.3095
377 downloads
3,570 views

The abundant dinosaurian tracksites of the Lower Cretaceous (Valanginian–Barremian) Broome Sandstone of the Dampier Peninsula, Western Australia, form an important part of the West Kimberley National Heritage Place. Previous attempts to document these tracksites...

["Paleontology","Computational Science"]
doi:10.7717/peerj.3013
123 downloads
675 views

Hydrolysis of ATP by Na+/K+-ATPase, a P-Type ATPase, catalyzing active Na+ and K+ transport through cellular membranes leads transiently to a phosphorylation of its catalytical α-subunit. Surprisingly, three-dimensional molecular structure analysis of P-type ATPases...

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Computational Science"]
doi:10.7717/peerj.3087
72 downloads
313 views

Most of the previous studies on Weis-Fogh clap-fling mechanism have focused on the vortex structures and velocity fields. Detailed pressure distribution results are provided for the first time in this study to reveal the differences between the full and the partial...

["Biophysics","Computational Biology","Entomology","Mathematical Biology","Computational Science"]
doi:10.7717/peerj.3002
95 downloads
333 views

Background In the era of semantic web, life science ontologies play an important role in tasks such as annotating biological objects, linking relevant data pieces, and verifying data consistency. Understanding ontology structures and overlapping ontologies is essential...

["Bioinformatics","Computational Science"]
doi:10.7717/peerj.2990
240 downloads
1,039 views

Background De novo transcriptome assembly of short reads is now a common step in expression analysis of organisms lacking a reference genome sequence. Several software packages are available to perform this task. Even if their results are of good quality it is...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.2988
113 downloads
577 views

Bioinformaticians have implemented different strategies to distinguish cancer driver genes from passenger genes. One of the more recent advances uses a pathway-oriented approach. Methods that employ this strategy are highly dependent on the quality and size of...

["Bioinformatics","Computational Biology","Statistics","Computational Science"]
doi:10.7717/peerj.2568
118 downloads
553 views

The design of experiments and the validation of the results achieved with them are vital in any research study. This paper focuses on the use of different Machine Learning approaches for regression tasks in the field of Computational Intelligence and especially...

["Bioinformatics","Computational Biology","Molecular Biology","Statistics","Computational Science"]
doi:10.7717/peerj.2721
147 downloads
541 views

Brain perfusion is of key importance to assess brain function. Modern CT scanners can acquire perfusion maps of the cerebral parenchyma in vivo at submillimeter resolution. These perfusion maps give insights into the hemodynamics of the cerebral parenchyma and...

["Radiology and Medical Imaging","Neurology","Computational Science"]
doi:10.7717/peerj.2683
207 downloads
1,457 views

There has been steady improvement in methods for capturing bioimages. However analysing these images still remains a challenge. The Python programming language provides a powerful and flexible environment for scientific computation. It has a wide range of supporting...

["Bioinformatics","Cell Biology","Computational Biology","Human-Computer Interaction","Computational Science"]
doi:10.7717/peerj.2674
1 citation
91 downloads
367 views

This study compares and evaluates the prediction of hepatitis in Guangxi Province, China by using back propagation neural networks based genetic algorithm (BPNN-GA), generalized regression neural networks (GRNN), and wavelet neural networks (WNN). In order to compare...

["Epidemiology","Hematology","Infectious Diseases","Computational Science"]
doi:10.7717/peerj.2684

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