Peer-reviewed Articles - General

34 downloads
281 views

Life science ontologies play an important role in Semantic Web. Given the diversity in fish species and the associated wealth of information, it is imperative to develop an ontology capable of linking and integrating this information in an automated fashion. As...

["Aquaculture, Fisheries and Fish Science","Bioinformatics","Computational Science"]
doi:10.7717/peerj.3811
30 downloads
201 views

A new method for automatic optic disc localization and segmentation is presented. The localization procedure combines vascular and brightness information to provide the best estimate of the optic disc center which is the starting point for the segmentation algorithm....

["Ophthalmology","Radiology and Medical Imaging","Human\u2013Computer Interaction","Computational Science"]
doi:10.7717/peerj.3763
36 downloads
245 views

A key step in the transformation of raw sequencing reads into biological insights is the trimming of adapter sequences and low-quality bases. Read trimming has been shown to increase the quality and reliability while decreasing the computational requirements of...

["Bioinformatics","Genomics","Computational Science"]
doi:10.7717/peerj.3720
103 downloads
441 views

Background In light of the rapid decrease in fossils fuel reserves and an increasing demand for energy, novel methods are required to explore alternative biofuel production processes to alleviate these pressures. A wide variety of molecules which can either be...

["Bioinformatics","Computational Science"]
doi:10.7717/peerj.3497
68 downloads
644 views

Gene Co-expression Network Analysis (GCNA) is a popular approach to analyze a collection of gene expression profiles. GCNA yields an assignment of genes to gene co-expression modules, a list of gene sets statistically over-represented in these modules, and a gene-to-gene...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.3678
93 downloads
549 views

Background This paper is a comment on the idea of matrix-free Cladistics. Demonstration of this idea’s efficiency is a major goal of the study. Within the proposed framework, the ordinary (phenetic) matrix is necessary only as “source” of Hennigian trees, not as...

["Bioinformatics","Taxonomy","Computational Science"]
doi:10.7717/peerj.3578
87 downloads
369 views

Transpedicular transdiscal screw fixation is an alternative technique used in lumbar spine fixation; however, it requires an accurate screw trajectory. The aim of this study is to design a novel 3D-printed custom drill guide and investigate its accuracy to guide...

["Bioengineering","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3564
94 downloads
465 views

Colorectal cancer (CRC) is the third commonest malignant tumor. Previous studies have revealed that the composition change of the human gut microbiome, measured by community diversity, is associated with the progression of CRC. However, a further question, whether...

["Computational Biology","Ecology","Microbiology","Computational Science"]
doi:10.7717/peerj.3383
78 downloads
476 views

The five community state types (CSTs) first identified by Ravel et al. (2011) offered a powerful scheme to classify the states of human vaginal microbial communities (HVMC). The classification is a significant advance because it devised an effective handle to deal...

["Bioinformatics","Ecology","Microbiology","Women\u2019s Health","Computational Science"]
doi:10.7717/peerj.3366
120 downloads
812 views

This paper uses X-ray computed tomography to track the mechanical response of a vertebrate (Barnacle goose) long bone subjected to an axial compressive load, which is increased gradually until failure. A loading rig was mounted in an X-ray computed tomography system...

["Bioengineering","Kinesiology","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3416
77 downloads
335 views

Background High talker variability (i.e., multiple voices in the input) has been found effective in training nonnative phonetic contrasts in adults. A small number of studies suggest that children also benefit from high-variability phonetic training with some evidence...

["Psychiatry and Psychology","Computational Science"]
doi:10.7717/peerj.3209
1 citation
191 downloads
649 views

The Ramachandran plot is important to structural biology as it describes a peptide backbone in the context of its dominant degrees of freedom—the backbone dihedral angles φ and ψ (Ramachandran, Ramakrishnan & Sasisekharan, 1963). Since its introduction, the Ramachandran...

["Computational Biology","Mathematical Biology","Computational Science"]
doi:10.7717/peerj.3327
406 downloads
1,969 views

Background The goals of this study were (1) to present the set of data evaluating running biomechanics (kinematics and kinetics), including data on running habits, demographics, and levels of muscle strength and flexibility made available at Figshare (DOI: 10.6084/m9.figshare.4543435);...

["Bioengineering","Neuroscience","Kinesiology","Computational Science"]
doi:10.7717/peerj.3298
148 downloads
956 views

Obstructive sleep apnea syndrome (OSAS) is a common clinical condition. The way that OSAS risk factors associate and converge is not a random process. As such, defining OSAS phenotypes fosters personalized patient management and population screening. In this paper,...

["Bioinformatics","Computational Biology","Health Policy","Respiratory Medicine","Computational Science"]
doi:10.7717/peerj.3289
55 downloads
404 views

Background Reduction of readmissions after discharge represents an important challenge for many hospitals and has attracted the interest of many researchers in the past few years. Most of the studies in this field focus on building cross-sectional predictive models...

["Diabetes and Endocrinology","Public Health","Computational Science"]
doi:10.7717/peerj.3230

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