Peer-reviewed Articles - Biology

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The same selective forces that give rise to rapid inter- and intraspecific divergence in snake venoms can also favor differences in venoms across life-history stages. Ontogenetic changes in venom composition are well known and widespread in snakes but have not...

["Genetics","Toxicology"]
doi:10.7717/peerj.3249
37 downloads
246 views

Background Essential oil components (EOCs) are molecules with interesting application in pest control, these have been evaluated against different insect pest from more than 100 years, but their practical use is rather limited. Thus, the enhancement of their bioavailability...

["Entomology","Environmental Sciences","Toxicology"]
doi:10.7717/peerj.3171
42 downloads
288 views

Metals are present in aquatic environments as a result of natural and anthropogenic inputs, and may induce toxicity to organisms. One of the main factors that influence this toxicity in fresh water is natural organic matter (NOM) but all NOMs are not the same in...

["Biochemistry","Environmental Sciences","Marine Biology","Toxicology"]
doi:10.7717/peerj.3141
42 downloads
263 views

Although neonicotinoids are targeted at insects, their predominant use as a seed dressing and their long persistence in soils mean that non-target soil organisms such as earthworms are likely to be chronically exposed to them. Chronic exposure may pose risks that...

["Agricultural Science","Entomology","Environmental Sciences","Toxicology"]
doi:10.7717/peerj.3177
97 downloads
334 views

Background The monocled cobra (Naja kaouthia) is a medically important venomous snake in Southeast Asia. Its venom has been shown to vary geographically in relation to venom composition and neurotoxic activity, indicating vast diversity of the toxin genes within...

["Genetics","Molecular Biology","Toxicology","Zoology"]
doi:10.7717/peerj.3142
62 downloads
378 views

Background Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey...

["Biochemistry","Developmental Biology","Molecular Biology","Toxicology"]
doi:10.7717/peerj.3109
61 downloads
344 views

Moult of feathers entails considerable physiological and energetic costs to an avian organism. Even under favourable feeding conditions, endogenous body stores and energy reserves of moulting birds are usually severely depleted. Thus, most species of birds separate...

["Animal Behavior","Ecology","Toxicology","Veterinary Medicine","Zoology"]
doi:10.7717/peerj.3057
70 downloads
310 views

Snakebite envenomings represent a neglected public health issue in many parts of the rural tropical world. Animal-derived antivenoms have existed for more than a hundred years and are effective in neutralizing snake venom toxins when timely administered. However,...

["Bioinformatics","Biotechnology","Toxicology","Immunology","Synthetic Biology"]
doi:10.7717/peerj.2924
2 citations
462 downloads
1,755 views

Background Seed-applied neonicotinoids are widely used in agriculture, yet their effects on non-target species remain incompletely understood. One important group of non-target species is arthropod natural enemies (predators and parasitoids), which contribute considerably...

["Agricultural Science","Ecology","Entomology","Environmental Sciences","Toxicology"]
doi:10.7717/peerj.2776
106 downloads
525 views

Background Licorice, a popular traditional Chinese medicine (TCM), is widely used to moderate the effects (detoxification) of other herbs in TCM and often combined with Fructus Psoraleae. However, the classical TCM book states that Fructus Psoraleae is incompatible...

["Cell Biology","Toxicology","Pharmacology"]
doi:10.7717/peerj.2723
260 downloads
626 views

Lithocholic acid (LCA) is a secondary bile acid that is selectively toxic to human neuroblastoma, breast and prostate cancer cells, whilst sparing normal cells. We previously reported that LCA inhibited cell viability and proliferation and induced apoptosis and...

["Toxicology","Oncology"]
doi:10.7717/peerj.2445
131 downloads
569 views

Hepatocyte growth factor (HGF) is a paracrine hormone that plays an important role in epithelial-mesenchymal transition. HGF secreted by mesenchymal cells affects many properties of epithelial cells, such as proliferation, motility, and morphology. HGF has been...

["Biochemistry","Cell Biology","Molecular Biology","Toxicology"]
doi:10.7717/peerj.2624
219 downloads
499 views

Selenium (Se) is an essential element with a small difference between physiological and toxic doses. To provide more effective and safe Se dosing regimens, as compared to dosing with ionic selenium, nanoparticle formulations have been developed. However, due to...

["Food Science and Technology","Toxicology","Pharmacology","Metabolic Sciences"]
doi:10.7717/peerj.2601
248 downloads
782 views

Background The wide use of pesticides raises concerns on the health risks associated with pesticide exposure. For developing countries, like Thailand, pesticide monitoring program (in vegetables and fruits) and also the maximum residue limits (MRL) regulation have...

["Agricultural Science","Environmental Sciences","Food Science and Technology","Toxicology","Nutrition"]
doi:10.7717/peerj.2432
113 downloads
418 views

Background Manganese (Mn) is widely used in industries including the manufacture of Mn-iron (Fe) alloy. Occupational Mn overexposure causes manganism. Mn is known to affect Fe metabolism; this study was designed to test the hypothesis that workers exposed to Mn...

["Environmental Sciences","Toxicology","Public Health"]
doi:10.7717/peerj.2413

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