Peer-reviewed Articles - Biology

10 downloads
133 views

Recently, a novel phenomenon of horizontal gene transfer of helicase-encoding sequence from positive-stranded RNA viruses to LINE transposons in insect genomes was described. TRAS family transposons encoding an ORF2 protein, which comprised all typical functional...

["Entomology","Genomics","Molecular Biology","Virology"]
doi:10.7717/peerj.3673
21 downloads
160 views

Background Hybridization between native and invasive species can facilitate introgression of native genes that increase invasive potential by providing exotic species with pre-adapted genes suitable for new environments. In this study we assessed the outcome of...

["Molecular Biology","Plant Science"]
doi:10.7717/peerj.3630
22 downloads
103 views

Calcineurin B-like (CBL) proteins, as calcium sensors, play pivotal roles in plant responses to diverse abiotic stresses and in growth and development through interaction with CBL-interacting protein kinases (CIPKs). However, knowledge about functions and evolution...

["Evolutionary Studies","Genomics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.3653
40 downloads
317 views

Deep-sea mussels of the genus Bathymodiolus are numerically dominant macrofauna in many cold seep and hydrothermal vent ecosystems worldwide, and they depend on organic carbon produced by symbionts present in the epithelial cells of the gills. Although Bathymodiolus...

["Marine Biology","Molecular Biology"]
doi:10.7717/peerj.3565
37 downloads
228 views

Oxidative damage is a major cause of lung diseases, including pulmonary fibrosis. Laminarin is a kind of polysaccharide extracted from brown algae and plays vital roles in various biological processes. However, the functions and mechanisms of laminarin in pulmonary...

["Molecular Biology","Clinical Trials","Internal Medicine","Otorhinolaryngology"]
doi:10.7717/peerj.3642
49 downloads
212 views

Quantitative reverse transcription PCR (qRT-PCR) has been an integral part of characterizing the immunity of Anopheles mosquitoes towards Plasmodium invasion. Two anti-Plasmodium factors of Anopheles, thioester-containing protein 1 (TEP1) and nitric oxide synthase...

["Molecular Biology","Parasitology"]
doi:10.7717/peerj.3577
56 downloads
240 views

Background Obesity, a common metabolic disease, is a known cause of male infertility due to its associated health risk. Long noncoding RNAs (lncRNAs) have also been reported to be associated with male reproductive diseases; however, their role in the association...

["Developmental Biology","Molecular Biology","Metabolic Sciences"]
doi:10.7717/peerj.3518
289 downloads
396 views

Correct identification of forensically important insects, such as flies in the family Calliphoridae, is a crucial step for them to be used as evidence in legal investigations. Traditional identification based on morphology has been effective, but has some limitations...

["Biodiversity","Entomology","Molecular Biology","Taxonomy","Veterinary Medicine"]
doi:10.7717/peerj.3516
43 downloads
421 views

Cleavage of mRNA molecules causes their rapid degradation, thereby playing an important role in regulation of gene expression and host genome defense from viruses and transposons in bacterial and eukaryotic cells. Current negative-readout, and repressor-based positive-readout...

["Bioengineering","Molecular Biology","Synthetic Biology"]
doi:10.7717/peerj.3602
148 downloads
829 views

Background Type II diabetes is a chronic health condition which is associated with skin conditions including chronic foot ulcers and an increased incidence of skin infections. The skin microbiome is thought to play important roles in skin defence and immune functioning....

["Microbiology","Molecular Biology","Diabetes and Endocrinology"]
doi:10.7717/peerj.3543
49 downloads
307 views

Background As the fifth most common cancer worldwide, Hepatocellular carcinoma (HCC) is also the third most common cause of cancer-related death in China. Several lncRNAs have been demonstrated to be associated with occurrence and prognosis of HCC. However, identification...

["Bioinformatics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3575
61 downloads
474 views

Breast cancer spheroids have been widely used as in vitro models of cancer stem cells (CSCs), yet little is known about their phenotypic characteristics and microRNAs (miRNAs) expression profiles. The objectives of this research were to evaluate the phenotypic...

["Cell Biology","Molecular Biology","Translational Medicine"]
doi:10.7717/peerj.3551
33 downloads
405 views

Background The ferric uptake regulator (Fur) is a transcription factor and the main regulator of iron acquisition in prokaryotes. When bound to ferric iron, Fur recognizes its DNA binding site and generally executes its function by repressing transcription of its...

["Bioinformatics","Genetics","Marine Biology","Microbiology","Molecular Biology"]
doi:10.7717/peerj.3461
2,072 downloads
570 views

Targeted qPCR and non-targeted amplicon sequencing of 16S rRNA genes within sediment layers identified the anaerobic ammonium oxidation (anammox) niche and characterized microbial community changes attributable to freshwater mussels. Anammox bacteria were normally...

["Aquaculture, Fisheries and Fish Science","Ecosystem Science","Marine Biology","Microbiology","Molecular Biology"]
doi:10.7717/peerj.3536
64 downloads
479 views

The fibronectin leucine rich transmembrane (FLRT) protein family consists in humans of 3 proteins, FLRT1, -2, and -3. The FLRT proteins contain two extracellular domains separated by an unstructured linker. The most membrane distal part is a leucine rich repeat...

["Biochemistry","Cell Biology","Molecular Biology","Neuroscience"]
doi:10.7717/peerj.3550

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