Peer-reviewed Articles - Biology

9 downloads
52 views

The use of multiple sampling areas in landscape genetic analysis has been recognized as a useful way of generalizing the patterns of environmental effects on organism gene flow. It reduces the variability in inference which can be substantially affected by the...

["Ecosystem Science","Entomology","Environmental Sciences","Molecular Biology","Spatial and Geographic Information Science"]
doi:10.7717/peerj.4135
39 downloads
241 views

Ocean warming is a major threat to coral reefs, leading to an increasing frequency and amplitude of coral bleaching events, where the coral and its algal symbiont associations breakdown. Long-term change and resilience of a symbiont community in coral juveniles...

["Biodiversity","Ecology","Marine Biology","Molecular Biology","Climate Change Biology"]
doi:10.7717/peerj.4055
47 downloads
359 views

Background In spite of the emergence of RNA sequencing (RNA-seq), microarrays remain in widespread use for gene expression analysis in the clinic. There are over 767,000 RNA microarrays from human samples in public repositories, which are an invaluable resource...

["Genomics","Molecular Biology"]
doi:10.7717/peerj.4133
185 downloads
612 views

Epigenetics has attracted considerable attention with respect to its potential value in many areas of agricultural production, particularly under conditions where the environment can be manipulated or natural variation exists. Here we introduce key concepts and...

["Aquaculture, Fisheries and Fish Science","Molecular Biology"]
doi:10.7717/peerj.4147
23 downloads
263 views

Pantoea stewartii subsp. stewartii is a Gram-negative proteobacterium that causes leaf blight and Stewart’s wilt disease in corn. Quorum sensing (QS) controls bacterial exopolysaccharide production that blocks water transport in the plant xylem at high bacterial...

["Agricultural Science","Genetics","Microbiology","Molecular Biology","Plant Science"]
doi:10.7717/peerj.4145
39 downloads
189 views

APOBEC3A and APOBEC3G cytidine deaminases inhibit viruses and endogenous retrotransposons. We recently demonstrated the novel cellular C-to-U RNA editing function of APOBEC3A and APOBEC3G. Both enzymes deaminate single-stranded DNAs at multiple TC or CC nucleotide...

["Molecular Biology"]
doi:10.7717/peerj.4136
30 downloads
197 views

The microtubule depolymerising kinesin-13, MCAK, is phosphorylated at residue T537 by Cdk1. This is the only known phosphorylation site within MCAK’s motor domain. To understand the impact of phosphorylation by Cdk1 on microtubule depolymerisation activity, we...

["Biochemistry","Biophysics","Molecular Biology"]
doi:10.7717/peerj.4034
43 downloads
338 views

Background Lung cancer is considered as one of the most frequent and deadly cancers with high mortality all around the world. It is critical to find new biomarkers for early diagnosis of lung cancer, especially lung squamous cell carcinoma (LUSC). The Cancer Genome...

["Bioinformatics","Genomics","Molecular Biology","Public Health"]
doi:10.7717/peerj.4101
43 downloads
211 views

Background Methylophaga nitratireducenticrescens strain JAM1 is a methylotrophic, marine bacterium that was isolated from a denitrification reactor treating a closed-circuit seawater aquarium. It can sustain growth under anoxic conditions by reducing nitrate (...

["Environmental Sciences","Microbiology","Molecular Biology","Biogeochemistry"]
doi:10.7717/peerj.4098
40 downloads
374 views

Hormones play an important role in the regulation of physiological, developmental and behavioural processes. Many of these mechanisms in insects, however, are still not well understood. One way to investigate hormonal regulation is to analyse gene expression patterns...

["Entomology","Genetics","Molecular Biology"]
doi:10.7717/peerj.4047
53 downloads
1,977 views

Previous studies have used the zebrafish to investigate the biology of lens crystallin proteins and their roles in development and disease. However, little is known about zebrafish α-crystallin promoter function, how it compares to that of mammals, or whether mammalian...

["Developmental Biology","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7717/peerj.4093
72 downloads
384 views

This paper describes the development and application of a suite of tools, called PBxplore, to analyze the dynamics and deformability of protein structures using Protein Blocks (PBs). Proteins are highly dynamic macromolecules, and a classical way to analyze their...

["Bioinformatics","Computational Biology","Molecular Biology"]
doi:10.7717/peerj.4013
80 downloads
350 views

Morphological differentiation among closely related species provides opportunities to study mechanisms shaping natural phenotypic variation. Here, we address variation in the orientation of melanin-colored body stripes in three cichlid species of the tribe Haplochromini....

["Aquaculture, Fisheries and Fish Science","Biodiversity","Evolutionary Studies","Molecular Biology","Zoology"]
doi:10.7717/peerj.4080
56 downloads
313 views

Background Clear cell renal cell carcinoma (ccRCC) is the most common and lethal cancer of the adult kidney. However, its pathogenesis has not been fully understood till now, which hinders the therapeutic development of ccRCC. NADH dehydrogenase (ubiquinone) 1...

["Genomics","Molecular Biology","Oncology"]
doi:10.7717/peerj.4065
125 downloads
704 views

Stony corals (Scleractinia) are marine invertebrates that form the foundation and framework upon which tropical reefs are built. The coral animal associates with a diverse microbiome comprised of dinoflagellate algae and other protists, bacteria, archaea, fungi...

["Genomics","Marine Biology","Microbiology","Molecular Biology","Virology"]
doi:10.7717/peerj.4054

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