Peer-reviewed Articles - Biology

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Background Snakes belonging to the Bothrops genus are vastly distributed in Central and South America and are responsible for most cases of reported snake bites in Latin America. The clinical manifestations of the envenomation caused by this genus are due to three...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.3203
6 downloads
89 views

Quantitative real-time reverse transcription PCR (RT-qPCR) has been widely used in the detection and quantification of gene expression levels because of its high accuracy, sensitivity, and reproducibility as well as its large dynamic range. However, the reliability...

["Agricultural Science","Molecular Biology","Plant Science"]
doi:10.7717/peerj.3260
48 downloads
368 views

Although numbers of cancer cell lines have been shown to be successfully reprogrammed into induced pluripotent stem cells (iPSCs), reprogramming Oral Squamous Cell Carcinoma (OSCC) to pluripotency in relation to its cancer cell type and the expression pattern of...

["Cell Biology","Molecular Biology","Oncology","Medical Genetics"]
doi:10.7717/peerj.3174
90 downloads
310 views

There is an urgent need to identify and understand the ecosystem services of pollination and seed dispersal provided by threatened mammals such as flying foxes. The first step towards this is to obtain comprehensive data on their diet. However, the volant and nocturnal...

["Biodiversity","Conservation Biology","Ecology","Genetics","Molecular Biology"]
doi:10.7717/peerj.3176
59 downloads
306 views

Alzheimer’s disease is a multifactorial disorder caused by the interaction of genetic, epigenetic and environmental factors. The formation of cytotoxic oligomers consisting of Aβ peptide is widely accepted as being one of the main key events triggering the development...

["Biophysics","Biotechnology","Cell Biology","Molecular Biology","Neuroscience"]
doi:10.7717/peerj.3086
97 downloads
334 views

Background The monocled cobra (Naja kaouthia) is a medically important venomous snake in Southeast Asia. Its venom has been shown to vary geographically in relation to venom composition and neurotoxic activity, indicating vast diversity of the toxin genes within...

["Genetics","Molecular Biology","Toxicology","Zoology"]
doi:10.7717/peerj.3142
72 downloads
387 views

The olfaction system of insects plays an important role in mediating various physiological behaviors, including locating hosts, avoiding predators, and recognizing mates and oviposition sites. Therefore, some key genes in the system present valuable opportunities...

["Entomology","Genomics","Molecular Biology"]
doi:10.7717/peerj.3157
48 downloads
280 views

Background The endocrinology of skeletal muscle is highly complex and many issues about hormone action in skeletal muscle are still unresolved. Aim of the work is to improve our knowledge on the relationship between skeletal muscle and 17β-estradiol. Methods The...

["Cell Biology","Molecular Biology","Veterinary Medicine"]
doi:10.7717/peerj.3124
52 downloads
382 views

Background Species identification is essential for controlling disease, understanding epidemiology, and to guide the implementation of phytosanitary measures against fungi from the genus Diaporthe. Accurate Diaporthe species separation requires using multi-loci...

["Microbiology","Molecular Biology","Mycology"]
doi:10.7717/peerj.3120
59 downloads
236 views

Background The introduction of exotic species can have serious consequences for marine ecosystems. On the shores of the Cantabrian Sea (North of Spain) there are no routine examinations of seaweeds that combine molecular and morphological methods for early detection...

["Biodiversity","Ecology","Genetics","Marine Biology","Molecular Biology"]
doi:10.7717/peerj.3116
193 downloads
897 views

DNA metabarcoding, the PCR-based profiling of natural communities, is becoming the method of choice for biodiversity monitoring because it circumvents some of the limitations inherent to traditional ecological surveys. However, potential sources of bias that can...

["Ecology","Molecular Biology"]
doi:10.7717/peerj.3006
62 downloads
378 views

Background Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey...

["Biochemistry","Developmental Biology","Molecular Biology","Toxicology"]
doi:10.7717/peerj.3109
186 downloads
947 views

Background Ancient protein sequences are increasingly used to elucidate the phylogenetic relationships between extinct and extant mammalian taxa. Here, we apply these recent developments to Middle Pleistocene bone specimens of the rhinoceros genus Stephanorhinus....

["Bioinformatics","Evolutionary Studies","Molecular Biology","Paleontology"]
doi:10.7717/peerj.3033
56 downloads
270 views

Background Dengue is a global human public health threat, causing severe morbidity and mortality. The occurrence of sequential infection by more than one serotype of dengue virus (DENV) is a major contributing factor for the induction of Dengue Hemorrhagic Fever...

["Molecular Biology","Virology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2970
1 citation
114 downloads
674 views

Degeneracy in the genetic code implies that different codons can encode the same amino acid. Usage preference of synonymous codons has been observed in all domains of life. There is much evidence suggesting that this bias has a major role on protein elongation...

["Bioinformatics","Genetics","Genomics","Molecular Biology","Statistics"]
doi:10.7717/peerj.3081

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