Peer-reviewed Articles - Biology

81 downloads
330 views

Background Obesity, a common metabolic disease, is a known cause of male infertility due to its associated health risk. Long noncoding RNAs (lncRNAs) have also been reported to be associated with male reproductive diseases; however, their role in the association...

["Developmental Biology","Molecular Biology","Metabolic Sciences"]
doi:10.7717/peerj.3518
75 downloads
445 views

Terrestrial eggs have evolved repeatedly in tropical anurans exposing embryos to the new threat of dehydration. Red-eyed treefrogs, Agalychnis callidryas, lay eggs on plants over water. Maternally provided water allows shaded eggs in humid sites to develop to hatching...

["Developmental Biology","Ecology","Zoology"]
doi:10.7717/peerj.3549
112 downloads
383 views

Melatonin is a unique multifunctional molecule that mediates reproductive functions in animals. In this study, we investigated the effects of melatonin on bovine parthenogenetic and androgenetic embryonic development, oocyte maturation, the reactive oxygen species...

["Cell Biology","Developmental Biology","Molecular Biology"]
doi:10.7717/peerj.3485
84 downloads
666 views

Background Fibroblast growth factors (FGFs) and their receptors (FGFRs) are involved in the development and function of multiple organs and organ systems, including the central nervous system (CNS). FGF signaling via FGFR1, one of the three FGFRs expressed in the...

["Cell Biology","Developmental Biology","Neuroscience"]
doi:10.7717/peerj.3519
53 downloads
255 views

Disturbance from the normal developmental trajectory of a trait during growth—the so-called developmental instability—can be observed morphologically through phenodeviants and subtle deviations from perfect symmetry (fluctuating asymmetry). This study investigates...

["Developmental Biology","Evolutionary Studies","Zoology","Anatomy and Physiology","Pathology"]
doi:10.7717/peerj.3359
69 downloads
328 views

The evolutionarily conserved Mediator complex is a critical player in regulating transcription. Comprised of approximately two dozen proteins, the Mediator integrates diverse regulatory signals through direct protein-protein interactions that, in turn, modulate...

["Cell Biology","Developmental Biology","Evolutionary Studies","Molecular Biology"]
doi:10.7717/peerj.3390
86 downloads
398 views

Long bone curvature in animal limbs has long been a subject of interest and much work has explored why long bones should be curved. However, the ‘when’ and ‘how’ of curvature development is poorly understood. It has been shown that the rat tibia fails to attain...

["Biophysics","Developmental Biology","Zoology"]
doi:10.7717/peerj.3386
157 downloads
422 views

Gerbera hybrida is a cut-flower crop of global importance, and an understanding of the mechanisms underlying petal development is vital for the continued commercial development of this plant species. Brassinosteroids (BRs), a class of phytohormones, are known to...

["Bioinformatics","Developmental Biology","Genetics","Plant Science"]
doi:10.7717/peerj.3382
86 downloads
318 views

Because transcription is the first step in the regulation of gene expression, understanding how transcription factors bind to their DNA binding motifs has become absolutely necessary. It has been shown that the promoters of genes with similar expression profiles...

["Bioinformatics","Computational Biology","Developmental Biology","Genomics"]
doi:10.7717/peerj.3389
134 downloads
397 views

Background The NDUFS4 gene encodes an 18-kD subunit of mitochondria complex I, and mutations in this gene lead to the development of a severe neurodegenerative disease called Leigh syndrome (LS) in humans. To investigate the disease phenotypes and molecular mechanisms...

["Developmental Biology","Molecular Biology"]
doi:10.7717/peerj.3339
105 downloads
761 views

Measuring sensory sensitivity is important in studying development and developmental disorders. However, with children, there is a need to balance reliable but lengthy sensory tasks with the child’s ability to maintain motivation and vigilance. We used simulations...

["Developmental Biology","Neuroscience","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.3231
228 downloads
905 views

Background Lepidosaurs, a group including rhynchocephalians and squamates, are one of the major clades of extant vertebrates. Although there has been extensive phylogenetic work on this clade, its interrelationships are a matter of debate. Morphological and molecular...

["Developmental Biology","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.3262
221 downloads
705 views

A small juvenile turtle is described from the Early Cretaceous Jehol Biota, shedding light on the juvenile morphology and ontogeny of Manchurochelys manchoukuoensis. Several juvenile features are uncovered, such as a small and circular carapace (less than half...

["Developmental Biology","Paleontology"]
doi:10.7717/peerj.3274
127 downloads
627 views

The appropriate timing of flowering is crucial for the reproductive success of plants. Hence, intricate genetic networks integrate various environmental and endogenous cues such as temperature or hormonal statues. These signals integrate into a network of floral...

["Bioinformatics","Computational Biology","Developmental Biology","Plant Science"]
doi:10.7717/peerj.3197
123 downloads
878 views

Background Fibroblast growth factors (FGFs) and their receptors (FGFRs) have numerous functions in the developing and adult central nervous system (CNS). For example, the FGFR1 receptor is important for proliferation and fate specification of radial glial cells...

["Developmental Biology","Neuroscience","Psychiatry and Psychology"]
doi:10.7717/peerj.3173

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