Peer-reviewed Articles - Biology

4 downloads
2 views

Background Oxytetracycline (OTC), which is largely employed in zootechnical and veterinary practices to ensure wellness of farmed animals, is partially absorbed within the gastrointestinal tract depositing in several tissues. Therefore, the potential OTC toxicity...

["Cell Biology","Allergy and Clinical Immunology","Drugs and Devices","Immunology","Pharmacology"]
doi:10.7717/peerj.3236
2 downloads
1 view

The secretory pathway in Plasmodium falciparum has evolved to transport proteins to the host cell membrane and to an endosymbiotic organelle, the apicoplast. The latter can occur via the ER or the ER-Golgi route. Here, we study these three routes using proteins...

["Cell Biology","Parasitology"]
doi:10.7717/peerj.3128
48 downloads
368 views

Although numbers of cancer cell lines have been shown to be successfully reprogrammed into induced pluripotent stem cells (iPSCs), reprogramming Oral Squamous Cell Carcinoma (OSCC) to pluripotency in relation to its cancer cell type and the expression pattern of...

["Cell Biology","Molecular Biology","Oncology","Medical Genetics"]
doi:10.7717/peerj.3174
59 downloads
306 views

Alzheimer’s disease is a multifactorial disorder caused by the interaction of genetic, epigenetic and environmental factors. The formation of cytotoxic oligomers consisting of Aβ peptide is widely accepted as being one of the main key events triggering the development...

["Biophysics","Biotechnology","Cell Biology","Molecular Biology","Neuroscience"]
doi:10.7717/peerj.3086
27 downloads
197 views

Our previous study demonstrated that tentacle extract (TE) from the jellyfish Cyanea capillata (C. capillata) could cause a weak relaxation response mediated by nitric oxide (NO) using isolated aorta rings. However, the intracellular mechanisms of TE-induced vasodilation...

["Cell Biology","Marine Biology","Cardiology"]
doi:10.7717/peerj.3172
48 downloads
280 views

Background The endocrinology of skeletal muscle is highly complex and many issues about hormone action in skeletal muscle are still unresolved. Aim of the work is to improve our knowledge on the relationship between skeletal muscle and 17β-estradiol. Methods The...

["Cell Biology","Molecular Biology","Veterinary Medicine"]
doi:10.7717/peerj.3124
61 downloads
332 views

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape...

["Cell Biology","Immunology","Pharmacology"]
doi:10.7717/peerj.3108
70 downloads
405 views

Background Cartilage tissue engineering is a fast-evolving field of biomedical engineering, in which the chondrocytes represent the most commonly used cell type. Since research in tissue engineering always consumes a lot of cells, simple and cheap isolation methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.3079
55 downloads
204 views

Background Death-associated protein kinase 1 (DAPK) is an important tumor suppressor kinase involved in the regulation of multiple cellular activities such as apoptosis and autophagy. DNA methylation of DAPK gene was found in various types of cancers and often...

["Cell Biology"]
doi:10.7717/peerj.3084
59 downloads
301 views

Calcineurin (CN) is a serine/threonine phosphatase which plays important roles in meiosis maturation in invertebrate oocytes; however, the role of CN in mouse oocytes is relatively unexplored. In this study, we examined the expression, localization and functional...

["Cell Biology","Developmental Biology"]
doi:10.7717/peerj.3032
68 downloads
342 views

Background Bax inhibitor-1 (BI-1) is an evolutionarily conserved cytoprotective transmembrane protein that acts as a suppressor of Bax-induced apoptosis by regulation of endoplasmic reticulum stress-induced cell death. We knocked down BI-1 in the sensitive dopa...

["Cell Biology","Genetics","Neuroscience"]
doi:10.7717/peerj.2974
166 downloads
614 views

The exoskeleton is an important source of characters for the taxonomy of Hydroidolina. It originates as epidermal secretions and, among other functions, protects the coenosarc of the polypoid stage. However, comparative studies on the exoskeletal tissue origin,...

["Cell Biology","Marine Biology","Taxonomy","Zoology","Histology"]
doi:10.7717/peerj.2964
86 downloads
440 views

Macrobrachium rosenbergii nodavirus (MrNv) poses a major threat to the prawn industry. Currently, no effective vaccine and treatment are available to prevent the spread of MrNv. Its infection mechanism and localisation in a host cell are also not well characterised....

["Biotechnology","Cell Biology","Microbiology","Molecular Biology","Virology"]
doi:10.7717/peerj.2947
210 downloads
1,221 views

Systematic studies of micronutrients during brain formation are hindered by restrictions to animal models and adult post-mortem tissues. Recently, advances in stem cell biology have enabled recapitulation of the early stages of human telencephalon development in...

["Cell Biology","Developmental Biology","Neuroscience"]
doi:10.7717/peerj.2927
108 downloads
247 views

Root hairs are unicellular elongations of certain rhizodermal cells that improve the uptake of sparingly soluble and immobile soil nutrients. Among different Arabidopsis thaliana genotypes, root hair density, length and the local acclimation to low inorganic phosphate...

["Agricultural Science","Cell Biology","Genetics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.2891

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