Peer-reviewed Articles - Biology

10 downloads
162 views

Objective The trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might be a viable therapeutic approach. Decellularized TM scaffolds have previously been produced...

["Bioengineering","Biotechnology","Ophthalmology"]
doi:10.7717/peerj.3629
54 downloads
423 views

This article describes a public data set containing the three-dimensional kinematics of the whole human body and the ground reaction forces (with a dual force platform setup) of subjects who were standing still for 60 s in different conditions, in which the subjects’...

["Bioengineering","Neuroscience","Kinesiology"]
doi:10.7717/peerj.3626
102 downloads
831 views

Background The ostrich is a cursorial bird with extraordinary speed and endurance, especially in the desert, and thus is an ideal large-scale animal model for mechanic study of locomotion on granular substrate. Methods The plantar pressure distributions of ostriches...

["Animal Behavior","Bioengineering","Biophysics"]
doi:10.7717/peerj.3613
44 downloads
308 views

Introduction Different types of headaches and TMJ click influence the masseter muscle activity. The aim of this study was to assess the trend of energy level of the electromyography (EMG) activity of the masseter muscle during open-close clench cycles in migraine...

["Bioengineering","Computational Biology","Evidence Based Medicine","Radiology and Medical Imaging","Translational Medicine"]
doi:10.7717/peerj.3556
45 downloads
424 views

Cleavage of mRNA molecules causes their rapid degradation, thereby playing an important role in regulation of gene expression and host genome defense from viruses and transposons in bacterial and eukaryotic cells. Current negative-readout, and repressor-based positive-readout...

["Bioengineering","Molecular Biology","Synthetic Biology"]
doi:10.7717/peerj.3602
55 downloads
297 views

Transpedicular transdiscal screw fixation is an alternative technique used in lumbar spine fixation; however, it requires an accurate screw trajectory. The aim of this study is to design a novel 3D-printed custom drill guide and investigate its accuracy to guide...

["Bioengineering","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3564
34 downloads
440 views

CodonGenie, freely available from http://codon.synbiochem.co.uk, is a simple web application for designing ambiguous codons to support protein mutagenesis applications. Ambiguous codons are derived from specific heterogeneous nucleotide mixtures, which create sequence...

["Bioengineering","Bioinformatics","Biotechnology","Computational Biology","Synthetic Biology"]
doi:10.7717/peerj-cs.120
50 downloads
295 views

Background Osteoprotegerin (OPG) is used for the systemic treatment of bone diseases, although it has many side effects. The aim of this study was to investigate a newly formulated OPG-chitosan gel for local application to repair bone defects. Recent studies have...

["Bioengineering","Orthopedics","Pharmacology"]
doi:10.7717/peerj.3513
70 downloads
334 views

Artifacts removal and rhythms extraction from electroencephalography (EEG) signals are important for portable and wearable EEG recording devices. Incorporating a novel grouping rule, we proposed an adaptive singular spectrum analysis (SSA) method for artifacts...

["Bioengineering","Computational Biology","Neuroscience"]
doi:10.7717/peerj.3474
95 downloads
473 views

Toxicity issues and biocompatibility concerns with traditional classical chemical cross-linking processes prevent them from being universal approaches for hydrogel fabrication for tissue engineering. Physical cross-linking methods are non-toxic and widely used...

["Bioengineering","Biotechnology"]
doi:10.7717/peerj.3498
98 downloads
762 views

This paper uses X-ray computed tomography to track the mechanical response of a vertebrate (Barnacle goose) long bone subjected to an axial compressive load, which is increased gradually until failure. A loading rig was mounted in an X-ray computed tomography system...

["Bioengineering","Kinesiology","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3416
283 downloads
1,595 views

Background The goals of this study were (1) to present the set of data evaluating running biomechanics (kinematics and kinetics), including data on running habits, demographics, and levels of muscle strength and flexibility made available at Figshare (DOI: 10.6084/m9.figshare.4543435);...

["Bioengineering","Neuroscience","Kinesiology","Computational Science"]
doi:10.7717/peerj.3298
70 downloads
304 views

Background Electrolytic ablation and electroporation based ablation are minimally invasive, non-thermal surgical technologies that employ electrical currents and electric fields to ablate undesirable cells in a volume of tissue. In this study, we explore the attributes...

["Bioengineering","Biophysics","Oncology","Pathology","Histology"]
doi:10.7717/peerj.3190
123 downloads
1,127 views

Background Kettlebell lifting has gained increased popularity as both a form of resistance training and as a sport, despite the paucity of literature validating its use as a training tool. Kettlebell sport requires participants to complete the kettlebell snatch...

["Bioengineering","Anatomy and Physiology","Kinesiology","Orthopedics"]
doi:10.7717/peerj.3111
159 downloads
588 views

Background Cartilage tissue engineering is a fast-evolving field of biomedical engineering, in which the chondrocytes represent the most commonly used cell type. Since research in tissue engineering always consumes a lot of cells, simple and cheap isolation methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.3079

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