Peer-reviewed Articles - Biology

15 downloads
111 views

Clostridium septicum produces a number of diseases in human and farm animals which, in most of the cases, are fatal without clinical intervention. Alpha toxin is an important agent and the unique lethal virulent factor produced by Clostridium septicum. This toxin...

["Biochemistry","Biotechnology"]
doi:10.7717/peerj.3407
18 downloads
105 views

Background Pharyngitis is an inflammatory condition of the pharynx and associated structures commonly caused by the Group A streptococci (GAS). There is a growing interest in discovering plant-based anti-inflammatory compounds as potential alternatives to conventional...

["Agricultural Science","Biochemistry","Cell Biology","Food Science and Technology","Infectious Diseases"]
doi:10.7717/peerj.3469
55 downloads
320 views

Photosynthates released by benthic primary producers (BPP), such as reef algae and scleractinian corals, fuel the dissolved organic carbon (DOC) production on tropical coral reefs. DOC concentrations near BPP have repeatedly been observed to be elevated compared...

["Biochemistry","Ecology","Environmental Sciences","Marine Biology"]
doi:10.7717/peerj.3456
54 downloads
297 views

TH(AGYLLGHINLHHLAHL(Aib)HHIL-NH2), a histidine-rich, cell-penetrating peptide with acid-activated pH response, designed and synthesized by our group, can effectively target tumor tissues with an acidic extracellular environment. Since the protonating effect of...

["Biochemistry","Cell Biology","Oncology"]
doi:10.7717/peerj.3429
55 downloads
267 views

The changes of protein expression that are monitored in proteomic experiments are a type of biological transformation that also involves changes in chemical composition. Accompanying the myriad molecular-level interactions that underlie any proteomic transformation,...

["Biochemistry","Mathematical Biology","Oncology"]
doi:10.7717/peerj.3421
57 downloads
328 views

Background Synthesis of thyroid hormones and regulation of their metabolism involve free radicals that may affect redox balance in the body. Thyroid disorders causing variations in the levels of thyroid hormones may alter cellular oxidative stress. The aim of this...

["Biochemistry","Molecular Biology","Oncology","Medical Genetics","Metabolic Sciences"]
doi:10.7717/peerj.3365
63 downloads
254 views

Background Several studies report aberrant expression of sine oculis homeobox (SIX) homolog family members during cancer development and progression. SIX4 participates in organ development, such as myogenesis and neurogenesis. However, the expression and clinical...

["Biochemistry","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3394
92 downloads
597 views

Background Bumblebees (Hymenoptera: Apidae: Bombus) are well known for their important inter- and intra-specific variation in hair (or pubescence) color patterns, but the chemical nature of the pigments associated with these patterns is not fully understood. For...

["Biochemistry","Entomology","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.3300
37 downloads
249 views

Biomarkers are the measurable changes associated with a physiological or pathophysiological process. The content of urine frequently changes because it is not controlled by homeostatic mechanisms, and these alterations can be a source of biomarkers. However, urine...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.3350
54 downloads
186 views

Coptis chinensis Franch., the Chinese goldthread (‘Weilian’ in Chinese), one of the most important medicinal plants from the family Ranunculaceae, and its rhizome has been widely used in Traditional Chinese Medicine for centuries. Here, we analyzed the chemical...

["Biochemistry","Bioinformatics","Computational Biology","Plant Science"]
doi:10.7717/peerj.3303
77 downloads
421 views

Background Obesity has become a worldwide burden to public health in recent decades. Given that obesity is caused by an imbalance between caloric intake and expenditure, and that dietary fat is the most important energy source of all macronutrients (by providing...

["Biochemistry","Food Science and Technology","Diabetes and Endocrinology","Nutrition"]
doi:10.7717/peerj.3279
71 downloads
217 views

Tuberculosis is one of the world’s deadliest infectious disease with 1.5 millions deaths annually. It is imperative to discover novel compounds with potent activity against M. tuberculosis. In this study, susceptibilities of M. smegmatis to the octahedral ruthenium(II)...

["Biochemistry","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3252
79 downloads
559 views

Mayaro virus (MAYV) is an emergent sylvatic alphavirus in South America, related to sporadic outbreaks of a chikungunya-like human febrile illness accompanied by severe arthralgia. Despite its high potential for urban emergence, MAYV is still an obscure virus with...

["Biochemistry","Microbiology","Virology","Infectious Diseases"]
doi:10.7717/peerj.3245
48 downloads
142 views

Background Snakes belonging to the Bothrops genus are vastly distributed in Central and South America and are responsible for most cases of reported snake bites in Latin America. The clinical manifestations of the envenomation caused by this genus are due to three...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.3203
88 downloads
332 views

Background Cell membrane permeabilization by pulsed electromagnetic fields (PEMF) is a novel contactless method which results in effects similar to conventional electroporation. The non-invasiveness of the methodology, independence from the biological object homogeneity...

["Biochemistry","Biophysics","Biotechnology"]
doi:10.7717/peerj.3267

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