Belonging to the order Atheriniformes, Craterocephalus is one of the most widespread genera of freshwater fishes in Australia, spanning along the northern coast from central Western Australia to central New South Wales and across the Murray-Darling and Lake Eyre...

["Aquaculture, Fisheries and Fish Science","Genetics","Molecular Biology","Zoology","Freshwater Biology"]
doi:10.7287/peerj.preprints.27688v1

Alzheimer’s disease (AD) is a significant health issue for the elderly and becoming increasingly common as the global population ages. Although many efforts have been made to elucidate its pathology, there is still a lack of effective clinical anti-AD agents. Previous...

["Drugs and Devices","Pharmacology"]
doi:10.7717/peerj.6716

Background The efficacy of emotional and motivational regulation can determine athletic performance. Giving the short duration and fast changing nature of emotions experienced by athletes in competition, it is important to examine the temporal dynamics of emotional...

["Neuroscience","Kinesiology"]
doi:10.7717/peerj.6777

Background Osteoporosis is a common, complex disease of bone with a strong heritable component, characterized by low bone mineral density, microarchitectural deterioration of bone tissue and an increased risk of fracture. Due to limited drug selection for osteoporosis...

["Bioinformatics","Medical Genetics"]
doi:10.7717/peerj.6778
1 download
1 view

Background Advantages of loop-mediated isothermal amplification in molecular diagnostics allow to consider the method as a promising technology of nucleic acid detection in agriculture and medicine. A bioinformatics tool that provides rapid screening and selection...

["Bioinformatics","Microbiology","Molecular Biology"]
doi:10.7717/peerj.6801
1 download
1 view

Background The incidences of premature coronary heart disease present a rising trend worldwide. The possible risk factors that may predict the incidence of repeat percutaneous coronary intervention (PCI) in premature acute coronary syndrome (ACS) remains unclear....

["Biochemistry","Cardiology"]
doi:10.7717/peerj.6804
2 downloads
2 views

Real-time quantitative reverse transcription-PCR (qRT-PCR) is an undeniably effective tool for measuring levels of gene expression, but the accuracy and reliability of the statistical data obtained depend mainly on the basal expression of selected housekeeping...

["Agricultural Science","Aquaculture, Fisheries and Fish Science","Biochemistry","Marine Biology"]
doi:10.7717/peerj.6834
5 downloads
28 views

Ocean warming threatens the functioning of coral reef ecosystems by inducing mass coral bleaching and mortality events. The link between temperature and coral bleaching is now well-established based on observations that mass bleaching events usually occur when...

["Marine Biology","Climate Change Biology","Biological Oceanography"]
doi:10.7287/peerj.preprints.27686v1
507 downloads
965 views

Detecting population declines is a critical task for conservation biology. The spatiotemporal variability of populations, along with logistical difficulties in population estimation, makes this task difficult. Here we call attention to a possible bias in estimates...

["Conservation Biology","Ecology","Natural Resource Management","Population Biology"]
doi:10.7287/peerj.preprints.27507v3
5 downloads
23 views

The electronic medical record (EMR) is a source of clinical information and is used for clinical research. Clinical researchers leverage this information by employing staffs to manually extracting data from the unstructured text. This process can be both error-prone...

["Epidemiology","Evidence Based Medicine"]
doi:10.7287/peerj.preprints.27685v1
22 downloads
29 views

Evidence-based medicine (EBM) involves determining treatment that matches the needs of each patient by integrating the best and latest available “scientific evidence” and “clinical skills”. Systematic review and meta-analysis refer to the process of searching databases...

["Epidemiology","Evidence Based Medicine"]
doi:10.7287/peerj.preprints.27684v1
17 downloads
49 views

While many microbes could be cultivated on common nutrient medium from environmental samples, there is perhaps a larger consortium of microbes that could not be brought under cultivation. Known as viable but non-culturable (VBNC) microbes, many facets of cell biology,...

["Biochemistry","Biotechnology","Cell Biology","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.27683v1
20 downloads
56 views

In the past decades a number of software programs have been developed to deduce the phylogenetic relationship between populations. However, these programs are not suited for large-scale whole genome data. Recently, a few standalone or web applications have been...

["Bioinformatics","Evolutionary Studies","Genetics","Genomics","Population Biology"]
doi:10.7287/peerj.preprints.27682v1
14 downloads
34 views

After decades of human-deterministic explanations for the collapse of the ancient Rapanui civilization that inhabited Easter Island (Rapa Nui) before European contact (1722 CE), paleoecological studies developed during the last decade have provided sound evidence...

["Ecology","Coupled Natural and Human Systems","Climate Change Biology","Environmental Impacts","Food, Water and Energy Nexus"]
doi:10.7287/peerj.preprints.27681v1
35 downloads
83 views

It has been well proved that melatonin participates in the regulation of the seasonal reproduction of ewes. However, the effects of short term treatment of melatonin on ewe’s ovulation are still to be clarified. In this study, the effects of melatonin on the number...

["Agricultural Science","Cell Biology","Developmental Biology"]
doi:10.7717/peerj.6750

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