300 downloads
473 views

Epidemics may both contribute to and arise as a result of conflict. The effects of conflict on infectious diseases are complex and there have been confounding observations of both increase and decrease in disease outbreaks during and after conflicts. However there...

["Computational Biology","Adaptive and Self-Organizing Systems","Agents and Multi-Agent Systems","Data Science","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.27651v6
67 downloads
106 views

A recent perspective has argued that the phrase “Necessary and Sufficient,” long a staple of the genetics literature, has been misapplied in the context of neuroscience, and should be abandoned (Yoshihara and Yoshihara, 2018). Here we rebut this proposal on both...

["Genetics","Neuroscience"]
doi:10.7287/peerj.preprints.27812v1
36 downloads
60 views

This paper describes a potential new explanation for Alzheimer’s disease (AD), referred to here as the lipid leakage model. It proposes that AD is caused by the influx of lipids following the breakdown of the blood brain barrier (BBB).The model argues that a principle...

["Biochemistry","Cell Biology","Microbiology","Molecular Biology","Neuroscience"]
doi:10.7287/peerj.preprints.27811v1
31 downloads
115 views

Background Diabetes mellitus type II (DMT-2) is a widely spread metabolic disorder both in developed and developing countries. The role of oxidative stress is well established in DMT-2 pathogenesis. The synthetic drugs for DMT-2 are associated with serious side...

["Biochemistry","Food Science and Technology","Plant Science","Evidence Based Medicine","Pharmacology"]
doi:10.7717/peerj.7022
75 downloads
104 views

Background More than 50 human placental proteins were isolated and physico-chemically characterized in the 70–80s by Hans Bohn and co-workers. Many of these proteins turned to have important role in placental functions and diagnostic significance in pregnancy complications....

["Gynecology and Obstetrics"]
doi:10.7717/peerj.6982
42 downloads
116 views

We present the complete mitochondrial genome of Paragonimus ohirai Miyazaki, 1939 and compare its features with those of previously reported mitochondrial genomes of the pathogenic lung-fluke, Paragonimus westermani, and other members of the genus. The circular...

["Genomics","Molecular Biology","Parasitology","Taxonomy"]
doi:10.7717/peerj.7031
41 downloads
108 views

Background Common prenatal ailments negatively impact performance of activities of daily living and it has been proposed that the use of dynamic elastomeric fabric orthoses, more commonly referred to as compression garments, during pregnancy might aid in the reduction...

["Evidence Based Medicine","Gynecology and Obstetrics","Kinesiology","Public Health","Women\u2019s Health"]
doi:10.7717/peerj.7080
116 downloads
148 views

Robustly delimited species are of paramount importance, the identification of which relies on our ability to discern boundaries between one species and the next. This is not difficult to do when species are very distinct from one another. However, in recently evolved...

["Biodiversity","Evolutionary Studies","Plant Science","Taxonomy"]
doi:10.7717/peerj.7090
67 downloads
113 views

Background Compared to chemical control, the use of naturally occurring biological agents to control invasive pests is less threatening to the environment and human health. Objectives Here, we assessed the ability of immature stages of the lacewing Ceraeochrysa...

["Agricultural Science","Animal Behavior","Ecology","Entomology","Zoology"]
doi:10.7717/peerj.7123
32 downloads
102 views

Hypericum perforatum L. is a widely known medicinal herb used mostly as a remedy for depression because it contains high levels of naphthodianthrones, phloroglucinols, alkaloids, and some other secondary metabolites. Quantitative real-time PCR (qRT-PCR) is an optimized...

["Bioinformatics","Molecular Biology","Plant Science","Data Mining and Machine Learning","Data Science"]
doi:10.7717/peerj.7133
52 downloads
104 views

Background Overweight (OW) is considered a risk for various metabolic diseases. However, its effects as a mechanism that alters the metabolite profiles remain unclear. The purpose of this study is to investigate the effects that OW has on the lipid and metabolite...

["Biochemistry","Biophysics","Diabetes and Endocrinology","Gastroenterology and Hepatology","Metabolic Sciences"]
doi:10.7717/peerj.7137
1,771 downloads
3,330 views

Background The Swiss National Science Foundation (SNSF) supports fundamental and use-inspired research in all disciplines. Peer reviewers assess the proposals submitted to the SNSF. We examined whether the gender of applicants and reviewers and other factors influenced...

["Science Policy"]
doi:10.7287/peerj.preprints.27587v3
50 downloads
136 views

Background Cholera, an acute enteric infection, is a serious health challenge in both the underdeveloped and the developing world. It is caused by Vibrio cholerae after ingestion of fecal contaminated food or water. Cholera outbreaks have recently been observed...

["Bioinformatics","Drugs and Devices","Immunology","Infectious Diseases"]
doi:10.7717/peerj.6223
123 downloads
139 views

The observed dynamics of infectious diseases are driven by processes across multiple scales. Here we focus on two: within-host, that is, how an infection progresses inside a single individual (for instance viral and immune dynamics), and between-host, that is,...

["Computational Biology","Mathematical Biology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.7057
115 downloads
143 views

Background Glyphosate is among the most extensively used pesticides worldwide. Following the ongoing highly controversial debate on this compound, its potential impact on non-target organisms is a fundamental scientific issue. In its pure compound form, glyphosate...

["Developmental Biology","Ecology","Ecotoxicology"]
doi:10.7717/peerj.7094

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