77 downloads
165 views

Carotenoid cleavage dioxygenases (CCDs) are enzymes that have been implicated in the biosynthesis of a wide diversity of secondary metabolites with important economic value, including bixin. Bixin is the second most used pigment in the world’s food industry worldwide,...

["Biochemistry","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7064
44 downloads
80 views

Background The Wnt signaling pathway, an evolutionarily conserved molecular transduction cascade, has been identified as playing a pivotal role in various physiological and pathological processes of the liver, including homeostasis, regeneration, cirrhosis, and...

["Molecular Biology","Gastroenterology and Hepatology","Hematology","Statistics","Medical Genetics"]
doi:10.7717/peerj.7073
53 downloads
115 views

Background Renal diseases represent a major public health problem. The demonstration that maladaptive repair of acute kidney injury (AKI) can lead to the development of chronic kidney disease (CKD) and end-stage renal disease has generated interest in studying...

["Nephrology","Metabolic Sciences"]
doi:10.7717/peerj.7113
52 downloads
112 views

Background Autonomous Sensory Meridian Response (ASMR) is a sensory-emotional experience in which specific stimuli (ASMR “triggers”) elicit tingling sensations on the scalp, neck, and shoulders; these sensations are accompanied by a positive affective state. In...

["Neuroscience","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.7122
47 downloads
86 views

Aims To explore molecular mechanisms that link peri-implantitis and type 2 diabetes mellitus (T2DM) by bioinformatic analysis of publicly available experimental transcriptomic data. Materials and methods Gene expression data from peri-implantitis were downloaded...

["Dentistry","Diabetes and Endocrinology","Computational Science"]
doi:10.7717/peerj.7124
31 downloads
124 views

Background The 2010 reform of the Italian university system introduced the National Scientific Habilitation (ASN) as a requirement for applying to permanent professor positions. Since the CVs of the 59,149 candidates and the results of their assessments have been...

["Data Science","Digital Libraries"]
doi:10.7717/peerj-cs.199
33 downloads
93 views

Background Sepsis is characterized by a pro-inflammatory and pro-coagulatory shift which can induce life-threatening complications. Close monitoring and risk stratification of sepsis patients is crucial for proper treatment and consequently patient outcome. Therefore,...

["Emergency and Critical Care","Hematology","Infectious Diseases"]
doi:10.7717/peerj.7147
41 downloads
49 views

Background Glioblastoma (GBM), the most malignant form of gliomas, is a relatively common primary brain tumor in adults. Preoperative identification of isocitrate dehydrogenase 1 (IDH1) mutations in GBM is of critical prognostic importance. The aim of the present...

["Biochemistry","Neurology","Oncology"]
doi:10.7717/peerj.7154
82 downloads
106 views

The initial decomposition of large floating-leaved macrophytes, such as waterlilies, can be studied by following changes in leaf damage and area loss of leaf blades tagged in their natural environment. This approach was taken in the present study to examine the...

["Agricultural Science","Ecology","Entomology","Freshwater Biology"]
doi:10.7717/peerj.7158
176 downloads
754 views

The Australian Mesozoic crocodyliform record is sparse in comparison to other Gondwanan localities. A single formally-named taxon is known from this interval; Isisfordia duncani (Winton Formation, Albian–Turonian, Queensland). We present a previously undescribed...

["Paleontology","Taxonomy"]
doi:10.7717/peerj.7166
55 downloads
76 views

Background Major depressive disorder (MDD) is a severe disease characterized by multiple pathological changes. However, there are no reliable diagnostic biomarkers for MDD. The aim of the current study was to investigate the gene network and biomarkers underlying...

["Cell Biology","Immunology","Psychiatry and Psychology"]
doi:10.7717/peerj.7171
73 downloads
70 views

Background Mallotus oblongifolius, an evergreen shrub endemic to Hainan Island, China, is important both medicinally and economically. Due to its special medicinal significance and the continuing rise of market demand, its populations in the wild have been subject...

["Agricultural Science","Conservation Biology","Genetics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7173
35 downloads
56 views

Background Extraintestinal manifestations (EIM) are common in ulcerative colitis (UC). In Shanghai, China, data on the incidence rate and risk factors of EIM in UC patients remain scarce. Methods The study population consisted of UC patients who were identified...

["Clinical Trials","Epidemiology","Gastroenterology and Hepatology","Immunology","Internal Medicine"]
doi:10.7717/peerj.7194
81 downloads
128 views

Attached epilithic foraminifera constitute an important but overlooked component of the benthic foraminiferal assemblage in the Pleistocene sediment of the central Arctic Ocean. We report 12 types of epilithic foraminifera that have colonised lithic and biogenic...

["Biodiversity","Marine Biology","Paleontology","Taxonomy"]
doi:10.7717/peerj.7207
84 downloads
268 views

We review the concept of ecosystem resilience in its relation to ecosystem integrity from an information theory approach. We summarize the literature on the subject identifying three main narratives: ecosystem properties that enable them to be more resilient; ecosystem...

["Ecology","Ecosystem Science","Mathematical Biology"]
doi:10.7287/peerj.preprints.27813v1

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