208 downloads
300 views

Background Gypsophila paniculata (baby’s breath) is an invasive species found throughout much of the northwest United States and western Canada. Recently, plants exhibiting a different color morphology were identified within the coastal dunes along eastern Lake...

["Conservation Biology","Plant Science"]
doi:10.7717/peerj.7100
390 downloads
195 views

Background Wheat is one of the most important staple crops worldwide. Fusarium head blight (FHB) severely affects wheat yield and quality. A novel bread wheat mutant, ZK001, characterized as cleistogamic was isolated from a non-cleistogamous variety Yumai 18 (YM18)...

["Molecular Biology","Plant Science"]
doi:10.7717/peerj.7104
307 downloads
141 views

The “bidirectional gene pair” indicates a particular head-to-head gene organization in which transcription start sites of two genes are located on opposite strands of genomic DNA within a region of one kb. Despite bidirectional gene pairs are well characterized,...

["Bioinformatics","Genomics"]
doi:10.7717/peerj.7107
69 downloads
130 views

Background Sepsis represents a significant healthcare problem worldwide and causes a high number of deaths every year but remains to be fully understood. During and after sepsis, the host immune response is complex and involves an initial excessive host inflammatory...

["Emergency and Critical Care","Hematology","Immunology","Infectious Diseases"]
doi:10.7717/peerj.7116
63 downloads
124 views

Neurotrophic receptor tyrosine kinase 2 (NTRK2) is a member of the tropomyosin receptor kinase family associated with the tumor development. However, the detailed function of NTRK2 in lung cancer, especially in lung adenocarcinoma (LUAD), is still not fully understood....

["Bioinformatics","Oncology","Pharmacology","Respiratory Medicine"]
doi:10.7717/peerj.7125
267 downloads
215 views

Protein–protein interactions are closely relevant to protein function and drug discovery. Hence, accurately identifying protein–protein interactions will help us to understand the underlying molecular mechanisms and significantly facilitate the drug discovery....

["Bioinformatics","Computational Biology","Data Mining and Machine Learning"]
doi:10.7717/peerj.7126
61 downloads
138 views

Selection from phage display libraries empowers isolation of high-affinity ligands for various targets. However, this method also identifies propagation-related target-unrelated peptides (PrTUPs). These false positive hits appear because of their amplification...

["Bioinformatics","Data Mining and Machine Learning"]
doi:10.7717/peerj.7131
131 downloads
73 views

Background Pulpitis is a common inflammatory disease that affects dental pulp. It is important to understand the molecular signals of inflammation and repair associated with this process. Increasing evidence has revealed that long noncoding RNAs (lncRNAs), via...

["Bioinformatics","Dentistry"]
doi:10.7717/peerj.7135
114 downloads
138 views

Background Insect neuropeptides are interesting for the potential their receptors hold as plausible targets for a novel generation of pesticides. Neuropeptide genes have been identified in a number of different species belonging to a variety of insects. Results...

["Bioinformatics","Entomology","Genomics","Neuroscience","Zoology"]
doi:10.7717/peerj.7144
94 downloads
112 views

Background Bile acids are important metabolites of intestinal microbiota, which have profound effects on host health. However, whether metabolism of bile acids is involved in the metabolic complications of end-stage renal disease (ESRD), and the effects of bile...

["Internal Medicine","Nephrology"]
doi:10.7717/peerj.7145
144 downloads
116 views

The Qinghai-Tibet Plateau (QTP) is experiencing severe permafrost degradation, which can affect the hydrological and biogeochemical processes. Yet how the permafrost change affects riverine carbon export remains uncertain. Here, we investigated the seasonal variations...

["Biogeochemistry","Environmental Impacts"]
doi:10.7717/peerj.7146
27 downloads
90 views

Background: Tick-borne diseases are frequent in the Southeastern section of Brazil. The most prevalent canine parasites diagnosed are Ehrlichia canis, Babesia gibsoni, Babesia canis and Anaplasma platys, although Mycoplasma haemocanis and candidatus Mycoplasma...

["Veterinary Medicine","Epidemiology"]
doi:10.7287/peerj.preprints.27805v1
91 downloads
114 views

The activity of genome-specific repetitive sequence is the main cause of the genome variation between Gossypium A and D genomes. Through the comparative analysis of the two genomes, we got a repetitive element (ICRd motif), which repeats massively in the diploid...

["Agricultural Science","Evolutionary Studies","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.27806v1
67 downloads
186 views

Sequencing data resources have increased exponentially in recent years, as has interest in large-scale meta-analyses of integrated next-generation sequencing datasets. However, curation of integrated datasets that match a user’s particular research priorities is...

["Bioinformatics","Data Science"]
doi:10.7287/peerj.preprints.27804v1
30 downloads
78 views

Background: L-Methionine sulfoximine (MSO) inhibits glutamine synthesis in a rodent animal model, and its limited clinical use is implicitly associated with glutamate deprivation and neurotoxicity. The purpose of this experiment was to determine the effect of MSO...

["Cell Biology","Toxicology","Drugs and Devices"]
doi:10.7287/peerj.preprints.27803v1

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