70 downloads
105 views

The fractal formalism in combination with linear image analysis enables statistically significant description and classification of “irregular” (in terms of Euclidean geometry) shapes, such as, outlines of in vitro flattened cells. We developed an optimal model...

["Bioinformatics","Cell Biology","Computational Biology","Marine Biology"]
doi:10.7717/peerj.7056
73 downloads
102 views

Background Ananas comosus var. bracteatus is an herbaceous perennial monocot cultivated as an ornamental plant for its chimeric leaves. Because of its genomic complexity, and because no genomic information is available in the public GenBank database, the complete...

["Agricultural Science","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7062
103 downloads
178 views

Carotenoid cleavage dioxygenases (CCDs) are enzymes that have been implicated in the biosynthesis of a wide diversity of secondary metabolites with important economic value, including bixin. Bixin is the second most used pigment in the world’s food industry worldwide,...

["Biochemistry","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7064
49 downloads
84 views

Background The Wnt signaling pathway, an evolutionarily conserved molecular transduction cascade, has been identified as playing a pivotal role in various physiological and pathological processes of the liver, including homeostasis, regeneration, cirrhosis, and...

["Molecular Biology","Gastroenterology and Hepatology","Hematology","Statistics","Medical Genetics"]
doi:10.7717/peerj.7073
54 downloads
120 views

Background Renal diseases represent a major public health problem. The demonstration that maladaptive repair of acute kidney injury (AKI) can lead to the development of chronic kidney disease (CKD) and end-stage renal disease has generated interest in studying...

["Nephrology","Metabolic Sciences"]
doi:10.7717/peerj.7113
59 downloads
118 views

Background Autonomous Sensory Meridian Response (ASMR) is a sensory-emotional experience in which specific stimuli (ASMR “triggers”) elicit tingling sensations on the scalp, neck, and shoulders; these sensations are accompanied by a positive affective state. In...

["Neuroscience","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.7122
53 downloads
93 views

Aims To explore molecular mechanisms that link peri-implantitis and type 2 diabetes mellitus (T2DM) by bioinformatic analysis of publicly available experimental transcriptomic data. Materials and methods Gene expression data from peri-implantitis were downloaded...

["Dentistry","Diabetes and Endocrinology","Computational Science"]
doi:10.7717/peerj.7124
88 downloads
152 views

Background The 2010 reform of the Italian university system introduced the National Scientific Habilitation (ASN) as a requirement for applying to permanent professor positions. Since the CVs of the 59,149 candidates and the results of their assessments have been...

["Data Science","Digital Libraries"]
doi:10.7717/peerj-cs.199
34 downloads
101 views

Background Sepsis is characterized by a pro-inflammatory and pro-coagulatory shift which can induce life-threatening complications. Close monitoring and risk stratification of sepsis patients is crucial for proper treatment and consequently patient outcome. Therefore,...

["Emergency and Critical Care","Hematology","Infectious Diseases"]
doi:10.7717/peerj.7147
42 downloads
58 views

Background Glioblastoma (GBM), the most malignant form of gliomas, is a relatively common primary brain tumor in adults. Preoperative identification of isocitrate dehydrogenase 1 (IDH1) mutations in GBM is of critical prognostic importance. The aim of the present...

["Biochemistry","Neurology","Oncology"]
doi:10.7717/peerj.7154
98 downloads
110 views

The initial decomposition of large floating-leaved macrophytes, such as waterlilies, can be studied by following changes in leaf damage and area loss of leaf blades tagged in their natural environment. This approach was taken in the present study to examine the...

["Agricultural Science","Ecology","Entomology","Freshwater Biology"]
doi:10.7717/peerj.7158
210 downloads
881 views

The Australian Mesozoic crocodyliform record is sparse in comparison to other Gondwanan localities. A single formally-named taxon is known from this interval; Isisfordia duncani (Winton Formation, Albian–Turonian, Queensland). We present a previously undescribed...

["Paleontology","Taxonomy"]
doi:10.7717/peerj.7166
86 downloads
80 views

Background Major depressive disorder (MDD) is a severe disease characterized by multiple pathological changes. However, there are no reliable diagnostic biomarkers for MDD. The aim of the current study was to investigate the gene network and biomarkers underlying...

["Cell Biology","Immunology","Psychiatry and Psychology"]
doi:10.7717/peerj.7171
133 downloads
81 views

Background Mallotus oblongifolius, an evergreen shrub endemic to Hainan Island, China, is important both medicinally and economically. Due to its special medicinal significance and the continuing rise of market demand, its populations in the wild have been subject...

["Agricultural Science","Conservation Biology","Genetics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7173
51 downloads
58 views

Background Extraintestinal manifestations (EIM) are common in ulcerative colitis (UC). In Shanghai, China, data on the incidence rate and risk factors of EIM in UC patients remain scarce. Methods The study population consisted of UC patients who were identified...

["Clinical Trials","Epidemiology","Gastroenterology and Hepatology","Immunology","Internal Medicine"]
doi:10.7717/peerj.7194

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