270 downloads
360 views

In this review, it is suggested that there are connections between hormonal changes, the frequency of DNA methylation, and disease. The commensal microbes of the gut may also affect the production of those hormones. Short Chain Fatty Acids, produced from gut microbiota...

["Microbiology","Molecular Biology","Immunology","Infectious Diseases","Synthetic Biology"]
doi:10.7287/peerj.preprints.27509v2
109 downloads
253 views

Grassland restoration is largely focused on creating plant communities that match reference conditions. However, these communities reflect only a subset of the biodiversity of grassland systems. We conducted a multi-trophic study to assess ecosystem recovery following...

["Biodiversity","Ecology","Environmental Impacts"]
doi:10.7717/peerj.7038
112 downloads
284 views

The amphibian skin microbiome has been the focus of recent studies aiming to better understand the role of these microbial symbionts in host defense against disease. However, host-associated microbial communities are complex and dynamic, and changes in their composition...

["Biodiversity","Conservation Biology","Ecology","Microbiology"]
doi:10.7717/peerj.7044
86 downloads
175 views

The fractal formalism in combination with linear image analysis enables statistically significant description and classification of “irregular” (in terms of Euclidean geometry) shapes, such as, outlines of in vitro flattened cells. We developed an optimal model...

["Bioinformatics","Cell Biology","Computational Biology","Marine Biology"]
doi:10.7717/peerj.7056
94 downloads
181 views

Background Ananas comosus var. bracteatus is an herbaceous perennial monocot cultivated as an ornamental plant for its chimeric leaves. Because of its genomic complexity, and because no genomic information is available in the public GenBank database, the complete...

["Agricultural Science","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7062
132 downloads
278 views

Carotenoid cleavage dioxygenases (CCDs) are enzymes that have been implicated in the biosynthesis of a wide diversity of secondary metabolites with important economic value, including bixin. Bixin is the second most used pigment in the world’s food industry worldwide,...

["Biochemistry","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7064
55 downloads
160 views

Background The Wnt signaling pathway, an evolutionarily conserved molecular transduction cascade, has been identified as playing a pivotal role in various physiological and pathological processes of the liver, including homeostasis, regeneration, cirrhosis, and...

["Molecular Biology","Gastroenterology and Hepatology","Hematology","Statistics","Medical Genetics"]
doi:10.7717/peerj.7073
63 downloads
162 views

Background Renal diseases represent a major public health problem. The demonstration that maladaptive repair of acute kidney injury (AKI) can lead to the development of chronic kidney disease (CKD) and end-stage renal disease has generated interest in studying...

["Nephrology","Metabolic Sciences"]
doi:10.7717/peerj.7113
70 downloads
189 views

Background Autonomous Sensory Meridian Response (ASMR) is a sensory-emotional experience in which specific stimuli (ASMR “triggers”) elicit tingling sensations on the scalp, neck, and shoulders; these sensations are accompanied by a positive affective state. In...

["Neuroscience","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.7122
63 downloads
149 views

Aims To explore molecular mechanisms that link peri-implantitis and type 2 diabetes mellitus (T2DM) by bioinformatic analysis of publicly available experimental transcriptomic data. Materials and methods Gene expression data from peri-implantitis were downloaded...

["Dentistry","Diabetes and Endocrinology","Computational Science"]
doi:10.7717/peerj.7124
111 downloads
228 views

Background The 2010 reform of the Italian university system introduced the National Scientific Habilitation (ASN) as a requirement for applying to permanent professor positions. Since the CVs of the 59,149 candidates and the results of their assessments have been...

["Data Science","Digital Libraries"]
doi:10.7717/peerj-cs.199
39 downloads
180 views

Background Sepsis is characterized by a pro-inflammatory and pro-coagulatory shift which can induce life-threatening complications. Close monitoring and risk stratification of sepsis patients is crucial for proper treatment and consequently patient outcome. Therefore,...

["Emergency and Critical Care","Hematology","Infectious Diseases"]
doi:10.7717/peerj.7147
45 downloads
107 views

Background Glioblastoma (GBM), the most malignant form of gliomas, is a relatively common primary brain tumor in adults. Preoperative identification of isocitrate dehydrogenase 1 (IDH1) mutations in GBM is of critical prognostic importance. The aim of the present...

["Biochemistry","Neurology","Oncology"]
doi:10.7717/peerj.7154
124 downloads
186 views

The initial decomposition of large floating-leaved macrophytes, such as waterlilies, can be studied by following changes in leaf damage and area loss of leaf blades tagged in their natural environment. This approach was taken in the present study to examine the...

["Agricultural Science","Ecology","Entomology","Freshwater Biology"]
doi:10.7717/peerj.7158
275 downloads
1,203 views

The Australian Mesozoic crocodyliform record is sparse in comparison to other Gondwanan localities. A single formally-named taxon is known from this interval; Isisfordia duncani (Winton Formation, Albian–Turonian, Queensland). We present a previously undescribed...

["Paleontology","Taxonomy"]
doi:10.7717/peerj.7166

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