92 downloads
165 views

Objective Environmental endocrine disruptors (EEDs) with a weak ability to mimic estrogen have been associated with thyroid dysfunction. However, little is known about the effect of nonylphenol (NP), a well-known EED, on thyroid structure. The present study evaluates...

["Toxicology","Public Health","Environmental Impacts"]
doi:10.7717/peerj.7039
77 downloads
196 views

Most people like symmetry, and symmetry has been extensively used in visual art and architecture. In this study, we compared preference for images of abstract and familiar objects in the original format or when containing perfect bilateral symmetry. We created...

["Psychiatry and Psychology"]
doi:10.7717/peerj.7078
214 downloads
337 views

Background Gypsophila paniculata (baby’s breath) is an invasive species found throughout much of the northwest United States and western Canada. Recently, plants exhibiting a different color morphology were identified within the coastal dunes along eastern Lake...

["Conservation Biology","Plant Science"]
doi:10.7717/peerj.7100
395 downloads
233 views

Background Wheat is one of the most important staple crops worldwide. Fusarium head blight (FHB) severely affects wheat yield and quality. A novel bread wheat mutant, ZK001, characterized as cleistogamic was isolated from a non-cleistogamous variety Yumai 18 (YM18)...

["Molecular Biology","Plant Science"]
doi:10.7717/peerj.7104
313 downloads
185 views

The “bidirectional gene pair” indicates a particular head-to-head gene organization in which transcription start sites of two genes are located on opposite strands of genomic DNA within a region of one kb. Despite bidirectional gene pairs are well characterized,...

["Bioinformatics","Genomics"]
doi:10.7717/peerj.7107
77 downloads
201 views

Background Sepsis represents a significant healthcare problem worldwide and causes a high number of deaths every year but remains to be fully understood. During and after sepsis, the host immune response is complex and involves an initial excessive host inflammatory...

["Emergency and Critical Care","Hematology","Immunology","Infectious Diseases"]
doi:10.7717/peerj.7116
68 downloads
141 views

Neurotrophic receptor tyrosine kinase 2 (NTRK2) is a member of the tropomyosin receptor kinase family associated with the tumor development. However, the detailed function of NTRK2 in lung cancer, especially in lung adenocarcinoma (LUAD), is still not fully understood....

["Bioinformatics","Oncology","Pharmacology","Respiratory Medicine"]
doi:10.7717/peerj.7125
276 downloads
282 views

Protein–protein interactions are closely relevant to protein function and drug discovery. Hence, accurately identifying protein–protein interactions will help us to understand the underlying molecular mechanisms and significantly facilitate the drug discovery....

["Bioinformatics","Computational Biology","Data Mining and Machine Learning"]
doi:10.7717/peerj.7126
68 downloads
170 views

Selection from phage display libraries empowers isolation of high-affinity ligands for various targets. However, this method also identifies propagation-related target-unrelated peptides (PrTUPs). These false positive hits appear because of their amplification...

["Bioinformatics","Data Mining and Machine Learning"]
doi:10.7717/peerj.7131
133 downloads
126 views

Background Pulpitis is a common inflammatory disease that affects dental pulp. It is important to understand the molecular signals of inflammation and repair associated with this process. Increasing evidence has revealed that long noncoding RNAs (lncRNAs), via...

["Bioinformatics","Dentistry"]
doi:10.7717/peerj.7135
122 downloads
191 views

Background Insect neuropeptides are interesting for the potential their receptors hold as plausible targets for a novel generation of pesticides. Neuropeptide genes have been identified in a number of different species belonging to a variety of insects. Results...

["Bioinformatics","Entomology","Genomics","Neuroscience","Zoology"]
doi:10.7717/peerj.7144
96 downloads
152 views

Background Bile acids are important metabolites of intestinal microbiota, which have profound effects on host health. However, whether metabolism of bile acids is involved in the metabolic complications of end-stage renal disease (ESRD), and the effects of bile...

["Internal Medicine","Nephrology"]
doi:10.7717/peerj.7145
148 downloads
140 views

The Qinghai-Tibet Plateau (QTP) is experiencing severe permafrost degradation, which can affect the hydrological and biogeochemical processes. Yet how the permafrost change affects riverine carbon export remains uncertain. Here, we investigated the seasonal variations...

["Biogeochemistry","Environmental Impacts"]
doi:10.7717/peerj.7146
38 downloads
106 views

Background: Tick-borne diseases are frequent in the Southeastern section of Brazil. The most prevalent canine parasites diagnosed are Ehrlichia canis, Babesia gibsoni, Babesia canis and Anaplasma platys, although Mycoplasma haemocanis and candidatus Mycoplasma...

["Veterinary Medicine","Epidemiology"]
doi:10.7287/peerj.preprints.27805v1
110 downloads
141 views

The activity of genome-specific repetitive sequence is the main cause of the genome variation between Gossypium A and D genomes. Through the comparative analysis of the two genomes, we got a repetitive element (ICRd motif), which repeats massively in the diploid...

["Agricultural Science","Evolutionary Studies","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.27806v1

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