73 downloads
73 views

Background Bile acids are important metabolites of intestinal microbiota, which have profound effects on host health. However, whether metabolism of bile acids is involved in the metabolic complications of end-stage renal disease (ESRD), and the effects of bile...

["Internal Medicine","Nephrology"]
doi:10.7717/peerj.7145
126 downloads
60 views

The Qinghai-Tibet Plateau (QTP) is experiencing severe permafrost degradation, which can affect the hydrological and biogeochemical processes. Yet how the permafrost change affects riverine carbon export remains uncertain. Here, we investigated the seasonal variations...

["Biogeochemistry","Environmental Impacts"]
doi:10.7717/peerj.7146
20 downloads
68 views

Background: Tick-borne diseases are frequent in the Southeastern section of Brazil. The most prevalent canine parasites diagnosed are Ehrlichia canis, Babesia gibsoni, Babesia canis and Anaplasma platys, although Mycoplasma haemocanis and candidatus Mycoplasma...

["Veterinary Medicine","Epidemiology"]
doi:10.7287/peerj.preprints.27805v1
86 downloads
93 views

The activity of genome-specific repetitive sequence is the main cause of the genome variation between Gossypium A and D genomes. Through the comparative analysis of the two genomes, we got a repetitive element (ICRd motif), which repeats massively in the diploid...

["Agricultural Science","Evolutionary Studies","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.27806v1
51 downloads
157 views

Sequencing data resources have increased exponentially in recent years, as has interest in large-scale meta-analyses of integrated next-generation sequencing datasets. However, curation of integrated datasets that match a user’s particular research priorities is...

["Bioinformatics","Data Science"]
doi:10.7287/peerj.preprints.27804v1
27 downloads
66 views

Background: L-Methionine sulfoximine (MSO) inhibits glutamine synthesis in a rodent animal model, and its limited clinical use is implicitly associated with glutamate deprivation and neurotoxicity. The purpose of this experiment was to determine the effect of MSO...

["Cell Biology","Toxicology","Drugs and Devices"]
doi:10.7287/peerj.preprints.27803v1
54 downloads
146 views

For the 2018 YPIC Challenge contestants were invited to try to decipher two unknown English questions encoded by a synthetic protein expressed in Escherichia coli. In addition to deciphering the sentence, contestants were asked to determine the 3D structure and...

["Bioinformatics","Molecular Biology"]
doi:10.7287/peerj.preprints.27802v1
17 downloads
32 views

It is important to get data with Signal-Noise-Ratios (SNR) as high as possible. Compared to other techniques, filtering methods are fast. But they do not make full use of the characteristics of sample structure which reflected by relevant high SNR images. In this...

["Computer Vision","Visual Analytics"]
doi:10.7287/peerj.preprints.27800v1
45 downloads
103 views

The expansion of research in forensic neuropsychiatric practice has led to several developments with an interdisciplinary focus in legal systems and psychiatry around the globe. Given the dearth of scientometric analyses in this area, this article will help increase...

["Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27799v1
153 downloads
307 views

Metabarcoding can rapidly determine the species composition of bulk samples and thus aids ecosystem assessment. However , it is essential to use primer sets that minimize amplification bias among taxa to maximize species recovery. Despite this fact, the performance...

["Ecology","Ecosystem Science","Entomology","Molecular Biology","Forestry"]
doi:10.7287/peerj.preprints.27801v1
51 downloads
184 views

Background Processed seafood products are not readily identifiable based on physical characteristics, which leaves the industry vulnerable to high levels of product mislabelling (globally estimated at 5–30% mislabelled). This is both a food safety issue and a consumer...

["Aquaculture, Fisheries and Fish Science","Biodiversity","Taxonomy","Science and Medical Education","Natural Resource Management"]
doi:10.7717/peerj.7138
98 downloads
166 views

The increase in greenhouse gases with high global warming potential such as methane is a matter of concern and requires multifaceted efforts to reduce its emission and increase its mitigation from the environment. Microbes such as methanotrophs can assist in methane...

["Bioinformatics","Microbiology","Synthetic Biology","Computational Science"]
doi:10.7717/peerj.6685
76 downloads
103 views

Background The soil fungal community plays an important role in global carbon cycling and shows obvious seasonal variations, however, drivers, particularly stochastic drivers, of the seasonal variation in the fungal community have never been addressed in sufficient...

["Ecosystem Science","Microbiology","Soil Science"]
doi:10.7717/peerj.6962
79 downloads
260 views

Emerging infectious diseases are an increasingly important threat to wildlife conservation, with amphibian chytridiomycosis, caused by Batrachochytrium dendrobatidis, the disease most commonly associated with species declines and extinctions. However, some amphibians...

["Conservation Biology","Ecology","Zoology"]
doi:10.7717/peerj.7021
146 downloads
120 views

Clade A type 2C protein phosphatases (PP2CAs), as central regulators of abscisic acid (ABA) signaling, negative control growth, development and responses to multiple stresses in plants. PP2CA gene families have been characterized at genome-wide levels in several...

["Agricultural Science","Bioinformatics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.7105

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