27 downloads
146 views

Wildlife collision data are ubiquitous, though challenging for making ecological inference due to typically irreducible uncertainty relating to the sampling process. We illustrate a new approach that is useful for generating inference from predator data arising...

["Conservation Biology","Ecology","Mathematical Biology","Statistics"]
doi:10.7717/peerj.3014
12 downloads
101 views

Interstitial lung disease (ILD) is a severe extra-articular manifestation of rheumatoid arthritis (RA) that is well-defined as a chronic systemic autoimmune disease. A proportion of patients with RA-associated ILD (RA-ILD) develop pulmonary fibrosis (PF), resulting...

["Immunology","Respiratory Medicine","Rheumatology","Statistics"]
doi:10.7717/peerj.3021
4 downloads
62 views

We studied the effect of linearization on the repeatability of the Tofts and reference region models (RRM) for Dynamic Contrast-Enhanced MRI (DCE MRI). We compared the repeatabilities of these two linearized models, the standard non-linear version, and semi-quantitative...

["Mathematical Biology","Radiology and Medical Imaging","Statistics"]
doi:10.7287/peerj.preprints.2824v1
14 downloads
74 views

The ecological niche concept has a revival interest under climate change, especially to study its impact on niche shift and/or conservatism. Here, we propose the Within Outlying Mean Indexes (WitOMI), which refines the Outlying Mean Index (OMI) analysis by using...

["Ecology","Statistics"]
doi:10.7287/peerj.preprints.2810v1
49 downloads
341 views

Background Colorectal cancer (CRC) is one of the leading cancers worldwide. Several studies have performed microarray data analyses for cancer classification and prognostic analyses. Microarray assays also enable the identification of gene signatures for molecular...

["Bioinformatics","Mathematical Biology","Molecular Biology","Oncology","Statistics"]
doi:10.7717/peerj.3003
28 downloads
98 views

We present survey questions useful for describing agricultural seed systems. The questions are designed so that they can be used for standardized comparisons among seed systems, addressing both networks for seed movement and networks for the communication of information...

["Agricultural Science","Microbiology","Plant Science","Statistics","Coupled Natural and Human Systems"]
doi:10.7287/peerj.preprints.2806v1
46 downloads
274 views

Background Several recent studies have shown that total scores on depressive symptom measures in a general population approximate an exponential pattern except for the lower end of the distribution. Furthermore, we confirmed that the exponential pattern is present...

["Epidemiology","Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.2987
209 downloads
1,028 views

Marker gene sequencing of microbial communities has generated big datasets of microbial relative abundances varying across environmental conditions, sample sites and treatments. These data often come with putative phylogenies, providing unique opportunities to...

["Computational Biology","Ecology","Mathematical Biology","Microbiology","Statistics"]
doi:10.7717/peerj.2969
5 downloads
75 views

Basic idea of science is reproducibility of phenomena and experiments. Reproducibility of data analyses and reports is becoming more and more important. It requires structured organization of data, augmented with enought metadata for future re-use of data. Our...

["Bioinformatics","Genomics","Plant Science","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2791v1
38 downloads
175 views

Objective: Trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might represent a novel therapeutic breakthrough. Various decellularized TM scaffolds were developed...

["Bioengineering","Ophthalmology","Statistics"]
doi:10.7287/peerj.preprints.2736v3
47 downloads
200 views

Background RNA sequencing (RNA-Seq) is a powerful technique for transcriptome profiling of the organisms that uses the capabilities of next-generation sequencing (NGS) technologies. Recent advances in NGS let to measure the expression levels of tens to thousands...

["Bioinformatics","Genomics","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2761v1
67 downloads
446 views

Bioinformaticians have implemented different strategies to distinguish cancer driver genes from passenger genes. One of the more recent advances uses a pathway-oriented approach. Methods that employ this strategy are highly dependent on the quality and size of...

["Bioinformatics","Computational Biology","Statistics","Computational Science"]
doi:10.7717/peerj.2568
3,948 downloads
8,584 views

We present the initial results of a reanalysis of four articles from the Cornell Food and Brand Lab based on data collected from diners at an Italian restaurant buffet. On a first glance at these articles, we immediately noticed a number of apparent inconsistencies...

["Ethical Issues","Science Policy","Statistics"]
doi:10.7287/peerj.preprints.2748v1
41 downloads
191 views

Site-specific evolutionary rates can be estimated from codon sequences or from amino-acid sequences. For codon sequences, the most popular methods use some variation of the dN/dS ratio. For amino-acid sequences, one widely-used method is called Rate4Site, and it...

["Bioinformatics","Computational Biology","Evolutionary Studies","Statistics"]
doi:10.7287/peerj.preprints.2739v1
93 downloads
277 views

This study was conducted to investigate the theory of dual coding on remembering words, by testing whether concrete words are better recalled than abstract words. A total of 298 (from Asian ethnicity) participants took part in this study. The participants were...

["Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2719v1

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