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histology
9 downloads
35 views

Chemotherapy is the mainstay in cancer treatment. Nevertheless, divergence of treatment responses exists across patients, often with the underlying mechanisms unknown. More disturbingly, some patients exhibits worsened outcome upon treatment. Genomic approaches...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v1
22 downloads
95 views

This study is aimed at characterizing soft tissue slices using a vibratome. In particular, the effect of two sectioning parameters (i.e., step size and sectioning speed) on resultant slice thickness was investigated for fresh porcine liver as well as for paraformaldehyde-fixed...

["Bioengineering","Anatomy and Physiology","Histology"]
doi:10.7717/peerj.932
40 downloads
283 views

Although modern baleen whales (Mysticeti) retain a functional olfactory system that includes olfactory bulbs, cranial nerve I and olfactory receptor genes, their olfactory capabilities have been reduced to a great degree. This reduction likely occurred as a selective...

["Evolutionary Studies","Neuroscience","Zoology","Anatomy and Physiology","Histology"]
doi:10.7717/peerj.897
77 downloads
384 views

Sponges have a remarkable capacity to rapidly regenerate in response to wound infliction. In addition, sponges rapidly renew their filter systems (choanocytes) to maintain a healthy population of cells. This study describes the cell kinetics of choanocytes in the...

["Cell Biology","Ecology","Marine Biology","Anatomy and Physiology","Histology"]
doi:10.7717/peerj.820
88 downloads
302 views

Torsional loading is a common feature of skeletal biomechanics during vertebrate flight. The importance of resisting torsional loads is best illustrated by the convergence of wing bone structure (e.g., long with thin walls) across extant bats and birds. Whether...

["Zoology","Anatomy and Physiology","Histology"]
doi:10.7717/peerj.823
47 downloads
41 views

Previous studies using the Golgi technique have demonstrated alterations in the dendritic morphology of pyramidal neurons of the cerebral cortex of mice inoculated with the rabies virus. However, knowledge about the fine structure of dendrites in rabies infection...

["Neuroscience","Virology","Infectious Diseases","Pathology","Histology"]
doi:10.7287/peerj.preprints.847v1
1 citation
107 downloads
298 views

The patella (kneecap) exhibits multiple evolutionary origins in birds, mammals, and lizards, and is thought to increase the mechanical advantage of the knee extensor muscles. Despite appreciable interest in the specialized anatomy and locomotion of palaeognathous...

["Evolutionary Studies","Paleontology","Histology"]
doi:10.7717/peerj.711
84 downloads
47 views

Although modern baleen whales still possess a functional olfactory systems that includes olfactory bulbs, cranial nerve I and olfactory receptor genes, their olfactory capabilities have been reduced profoundly. This is probably in response to their fully aquatic...

["Evolutionary Studies","Neuroscience","Zoology","Anatomy and Physiology","Histology"]
doi:10.7287/peerj.preprints.740v1
115 downloads
103 views

This study is aimed at characterizing soft tissue slices using a vibratome. In particular, the effect of two sectioning parameters (i.e. step size and sectioning speed) on resultant slice thickness was investigated for fresh porcine liver as well as for paraformaldehyde-fixed...

["Bioengineering","Anatomy and Physiology","Science and Medical Education","Histology"]
doi:10.7287/peerj.preprints.561v1
108 downloads
316 views

Poly-ADP-ribose (PAR) is a polymer of up to 400 ADP-ribose units synthesized by poly-ADP-ribose-polymerases (PARPs) and degraded by poly-ADP-ribose-glycohydrolase (PARG). Nuclear PAR modulates chromatin compaction, affecting nuclear functions (gene expression,...

["Cell Biology","Histology"]
doi:10.7717/peerj.617
2 citations
156 downloads
375 views

The threatened status (both ecologically and legally) of Caribbean staghorn coral, Acropora cervicornis, has prompted rapidly expanding efforts in culture and restocking, although tissue loss diseases continue to affect populations. In this study, disease surveillance...

["Conservation Biology","Ecology","Marine Biology","Histology"]
doi:10.7717/peerj.541
223 downloads
331 views

The patella (kneecap) exhibits multiple evolutionary origins in birds, mammals, and lizards, and is thought to increase the mechanical advantage of the knee extensor muscles. Despite appreciable interest in the specialized anatomy and locomotion of palaeognathous...

["Evolutionary Studies","Paleontology","Histology"]
doi:10.7287/peerj.preprints.404v1
1 citation
318 downloads
974 views

Bone microanalyses of extant vertebrates provide a necessary framework from which to form hypotheses regarding the growth and skeletochronology of extinct taxa. Here, we describe the bone microstructure and quantify the histovariability of appendicular elements...

["Histology","Paleontology"]
doi:10.7717/peerj.422
294 downloads
2,094 views

Reports have suggested that the two Notch ligands, Dll1 and Dll4, are indispensable to maintain the homeostasis of the intestinal epithelium. However, within the intestinal epithelium, the precise distribution of the cells that express those ligands at the protein...

["Histology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.370
2 citations
311 downloads
792 views

Therocephalians were a speciose clade of nonmammalian therapsids whose ecological diversity and survivorship of the end-Permian mass extinction offer the potential to investigate the evolution of growth patterns across the clade and their underlying influences...

["Evolutionary Studies","Histology","Paleontology"]
doi:10.7717/peerj.325

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