63 downloads
289 views

Background Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, proliferation...

["Cell Biology","Oncology","Histology"]
doi:10.7717/peerj.3754
371 downloads
1,505 views

Denticles are small, tooth-like protrusions that are commonly found on the palate of early tetrapods. Despite their widespread taxonomic occurrence and similar external morphology to marginal teeth, it has not been rigorously tested whether denticles are structurally...

["Paleontology","Histology"]
doi:10.7717/peerj.3727
95 downloads
590 views

Understanding how individual photoreceptor cells factor in the spectral sensitivity of a visual system is essential to explain how they contribute to the visual ecology of the animal in question. Existing methods that model the absorption of visual pigments use...

["Animal Behavior","Ecology","Neuroscience","Zoology","Histology"]
doi:10.7717/peerj.3595
70 downloads
423 views

The death-associated protein kinase 1 (DAPK1) can act as an oncogene or a tumor suppressor gene depending on the cellular context as well as external stimuli. Our study aims to investigate the prognostic significance of DAPK1 in liver cancer in both mRNA and protein...

["Biochemistry","Gastroenterology and Hepatology","Oncology","Translational Medicine","Histology"]
doi:10.7717/peerj.3568
42 downloads
252 views

Background: Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, proliferation...

["Cell Biology","Histology"]
doi:10.7287/peerj.preprints.2984v1
149 downloads
352 views

Background Poly-ADP-ribose (PAR) is a polymer synthesized by poly-ADP-ribose polymerases (PARPs) as a postranslational protein modification and catabolized mainly by poly-ADP-ribose glycohydrolase (PARG). In spite of the existence of cytoplasmic PARPs and PARG,...

["Cell Biology","Neuroscience","Histology"]
doi:10.7717/peerj.3318
211 downloads
722 views

New Pleistocene fossilized turtle remains from five localities of western Ecuador (Santa Elena Province) are described here. All these shell (carapace and plastron) fossil remains come from the Tablazo Formation and belong to three different lineages of cryptodires...

["Biodiversity","Evolutionary Studies","Paleontology","Taxonomy","Histology"]
doi:10.7717/peerj.3215
82 downloads
329 views

Background Electrolytic ablation and electroporation based ablation are minimally invasive, non-thermal surgical technologies that employ electrical currents and electric fields to ablate undesirable cells in a volume of tissue. In this study, we explore the attributes...

["Bioengineering","Biophysics","Oncology","Pathology","Histology"]
doi:10.7717/peerj.3190
260 downloads
1,200 views

Metoposaurids are temnospondyl amphibians that are commonly recovered from the Chinle Formation deposits of North America. Two species, Koskinonodon perfectus and Apachesaurus gregorii, are known from Petrified Forest National Park (PEFO), AZ. Small, elongate intercentra...

["Evolutionary Studies","Paleontology","Taxonomy","Histology"]
doi:10.7717/peerj.3183
173 downloads
572 views

Objective This study aimed to quantify the cartilage- and subchondral bone-related effects of low-dose and high-dose meloxicam treatment in the late phase of mono-iodoacetate-induced osteoarthritis of the stifle. Methods Thirty-four male Wistar rats received intra-articular...

["Pathology","Pharmacology","Rheumatology","Histology"]
doi:10.7717/peerj.3185
113 downloads
517 views

Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal growth factor receptor), results from previous...

["Oncology","Pathology","Histology"]
doi:10.7717/peerj.3140
35 downloads
230 views

Insecticidal crystal (Cry) proteins produced by the bacterium Bacillus thuringiensis (Bt) target cells in the midgut epithelium of susceptible larvae. While the mode of action of Cry toxins has been extensively investigated, the midgut response to Cry intoxication...

["Entomology","Microbiology","Histology"]
doi:10.7287/peerj.preprints.2878v1
349 downloads
1,757 views

Fragmentary caudal ends of the left and right mandible assigned to Lesothosaurus diagnosticus, an early ornithischian, was recently discovered in the continental red bed succession of the upper Elliot Formation (Lower Jurassic) at Likhoele Mountain (Mafeteng District)...

["Paleontology","Histology"]
doi:10.7717/peerj.3054
254 downloads
768 views

Tartrazine is a synthetic organic azo dye widely used in food and pharmaceutical products. The current study aimed to evaluate the possible adverse effect of this coloring food additive on renal and hepatic structures and functions. Also, the genotoxic potential...

["Biochemistry","Molecular Biology","Zoology","Histology"]
doi:10.7717/peerj.3041
1 citation
217 downloads
844 views

The exoskeleton is an important source of characters for the taxonomy of Hydroidolina. It originates as epidermal secretions and, among other functions, protects the coenosarc of the polypoid stage. However, comparative studies on the exoskeletal tissue origin,...

["Cell Biology","Marine Biology","Taxonomy","Zoology","Histology"]
doi:10.7717/peerj.2964

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