22 downloads
246 views

Understanding how individual photoreceptor cells factor in the spectral sensitivity of a visual system is essential to explain how they contribute to the visual ecology of the animal in question. Existing methods that model the absorption of visual pigments use...

["Animal Behavior","Ecology","Neuroscience","Zoology","Histology"]
doi:10.7717/peerj.3595
19 downloads
195 views

The death-associated protein kinase 1 (DAPK1) can act as an oncogene or a tumor suppressor gene depending on the cellular context as well as external stimuli. Our study aims to investigate the prognostic significance of DAPK1 in liver cancer in both mRNA and protein...

["Biochemistry","Gastroenterology and Hepatology","Oncology","Translational Medicine","Histology"]
doi:10.7717/peerj.3568
34 downloads
204 views

Background: Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, proliferation...

["Cell Biology","Histology"]
doi:10.7287/peerj.preprints.2984v1
106 downloads
286 views

Background Poly-ADP-ribose (PAR) is a polymer synthesized by poly-ADP-ribose polymerases (PARPs) as a postranslational protein modification and catabolized mainly by poly-ADP-ribose glycohydrolase (PARG). In spite of the existence of cytoplasmic PARPs and PARG,...

["Cell Biology","Neuroscience","Histology"]
doi:10.7717/peerj.3318
183 downloads
643 views

New Pleistocene fossilized turtle remains from five localities of western Ecuador (Santa Elena Province) are described here. All these shell (carapace and plastron) fossil remains come from the Tablazo Formation and belong to three different lineages of cryptodires...

["Biodiversity","Evolutionary Studies","Paleontology","Taxonomy","Histology"]
doi:10.7717/peerj.3215
63 downloads
282 views

Background Electrolytic ablation and electroporation based ablation are minimally invasive, non-thermal surgical technologies that employ electrical currents and electric fields to ablate undesirable cells in a volume of tissue. In this study, we explore the attributes...

["Bioengineering","Biophysics","Oncology","Pathology","Histology"]
doi:10.7717/peerj.3190
241 downloads
1,106 views

Metoposaurids are temnospondyl amphibians that are commonly recovered from the Chinle Formation deposits of North America. Two species, Koskinonodon perfectus and Apachesaurus gregorii, are known from Petrified Forest National Park (PEFO), AZ. Small, elongate intercentra...

["Evolutionary Studies","Paleontology","Taxonomy","Histology"]
doi:10.7717/peerj.3183
154 downloads
461 views

Objective This study aimed to quantify the cartilage- and subchondral bone-related effects of low-dose and high-dose meloxicam treatment in the late phase of mono-iodoacetate-induced osteoarthritis of the stifle. Methods Thirty-four male Wistar rats received intra-articular...

["Pathology","Pharmacology","Rheumatology","Histology"]
doi:10.7717/peerj.3185
88 downloads
435 views

Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal growth factor receptor), results from previous...

["Oncology","Pathology","Histology"]
doi:10.7717/peerj.3140
33 downloads
194 views

Insecticidal crystal (Cry) proteins produced by the bacterium Bacillus thuringiensis (Bt) target cells in the midgut epithelium of susceptible larvae. While the mode of action of Cry toxins has been extensively investigated, the midgut response to Cry intoxication...

["Entomology","Microbiology","Histology"]
doi:10.7287/peerj.preprints.2878v1
249 downloads
1,521 views

Fragmentary caudal ends of the left and right mandible assigned to Lesothosaurus diagnosticus, an early ornithischian, was recently discovered in the continental red bed succession of the upper Elliot Formation (Lower Jurassic) at Likhoele Mountain (Mafeteng District)...

["Paleontology","Histology"]
doi:10.7717/peerj.3054
188 downloads
673 views

Tartrazine is a synthetic organic azo dye widely used in food and pharmaceutical products. The current study aimed to evaluate the possible adverse effect of this coloring food additive on renal and hepatic structures and functions. Also, the genotoxic potential...

["Biochemistry","Molecular Biology","Zoology","Histology"]
doi:10.7717/peerj.3041
1 citation
198 downloads
718 views

The exoskeleton is an important source of characters for the taxonomy of Hydroidolina. It originates as epidermal secretions and, among other functions, protects the coenosarc of the polypoid stage. However, comparative studies on the exoskeletal tissue origin,...

["Cell Biology","Marine Biology","Taxonomy","Zoology","Histology"]
doi:10.7717/peerj.2964
35 downloads
132 views

Cancer spread away from the primary tumour towards other parts of the body is what is most feared in cancer treatment, and is the leading cause of relapse for patients who are in remission after initial rounds of treatment with surgery, radiation or chemotherapy....

["Biochemistry","Cell Biology","Marine Biology","Molecular Biology","Histology"]
doi:10.7287/peerj.preprints.2800v1
866 downloads
633 views

Divergence of treatment responses to chemotherapy exists across patients (often with unknown underlying mechanisms), with some patients exhibiting worsened outcome upon treatment. Genomic approaches (such as microarray profiling and whole genome sequencing) hold...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v6

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