3 downloads
33 views

Background. Viral metagenomics (viromics) is increasingly used to obtain uncultivated viral genomes, evaluate community diversity, and assess ecological hypotheses. While viromic experimental methods are relatively mature and widely accepted by the research community,...

["Bioinformatics","Ecology","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.3053v1
5 downloads
67 views

Potamopyrgus antipodarum, a New Zealand freshwater snail, is a powerful system to study the maintenance of sexual reproduction. Obligate asexual P. antipodarum (herein, Pa) lineages include both triploids and tetraploids that are products of multiple separate transitions...

["Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3046v1
6 downloads
58 views

Aminoacyl-tRNA synthetases (aaRS) are enzymes that catalyze the ligation of tRNAs to their cognate amino acids. There are aaRSs specific to each of the 20 standard amino acids. These enzymes are divided into two classes, class I and class II, which are unrelated...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3045v1
9 downloads
142 views

The advent of next-generation sequencing tools has made it possible to conduct fine-scale surveys of population differentiation and genome-wide scans for signatures of selection in non-model organisms. Such surveys are of particular importance in sharply declining...

["Conservation Biology","Genomics","Marine Biology"]
doi:10.7287/peerj.preprints.3043v1
11 downloads
66 views

Recently, Docker technology has received increasing attention throughout the bioinformatics community. However, its implementation has not yet been mastered by most biologists, and thus its application in biological research has been limited. In order to popularize...

["Bioinformatics","Computational Biology","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.3040v1
19 downloads
81 views

The Arabian Peninsula (AP) is the first site of human migration and habitation outside of Africa. As a major crossroad for human populations, the AP provides an opportunity to better understand early to modern changes in human demographic patterns through selections,...

["Bioinformatics","Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3039v1
6 downloads
155 views

Recent years have witnessed the discovery of protein–coding genes which appear to have evolved de novo from previously non-coding sequences. This has changed the long-standing view that coding sequences can only evolve from other coding sequences. However, there...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genetics","Genomics"]
doi:10.7287/peerj.preprints.3031v1
8 downloads
123 views

In de novo gene emergence, a segment of non-coding DNA undergoes a series of changes which enables transcription, potentially leading to a new protein that could eventually acquire a novel function. Due to their recent origins, young de novo genes have no homology...

["Bioinformatics","Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3030v1
51 downloads
587 views

Bariatric surgery is highly successful in improving health compared to conventional dietary treatments. It has been suggested that the gut microbiota is a relevant factor in weight loss after bariatric surgery. Considering that bariatric procedures cause different...

["Genomics","Microbiology","Gastroenterology and Hepatology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3443
34 downloads
300 views

Background Desiccation-tolerant (DT) plants can recover full metabolic competence upon rehydration after losing most of their cellular water (>95%) for extended periods of time. Functional genomic approaches such as transcriptome sequencing can help us understand...

["Genomics","Plant Science"]
doi:10.7717/peerj.3422
18 downloads
89 views

Background. The current study aims to explore the effects of advanced glycation end products (AGEs) on the microRNA (miRNA) expression profile in kidney tissues in a murine diabetic nephropathy (DN) model, and to investigate the possible underlying mechanisms....

["Genomics","Molecular Biology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.3026v1
86 downloads
309 views

Gastric cancer is an aggressive cancer that is often diagnosed late. Early detection and treatment require a better understanding of the molecular pathology of the disease. The present study combined data on gene expression and regulatory levels (microRNA, methylation,...

["Bioinformatics","Genetics","Genomics","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3385
51 downloads
409 views

Mitogen-activated protein kinases (MAPKs) are an important family of genes which play roles in vital plant processes, and they also help in coping against various kinds of environmental stresses including abiotic as well as biotic factors. The advancement of genomics...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genomics","Plant Science"]
doi:10.7717/peerj.3255
70 downloads
345 views

The ethylene-insensitive3/ethylene-insensitive3-like (EIN3/EIL) proteins are a type of nuclear-localized protein with DNA-binding activity in plants. Although the EIN3/EIL gene family has been studied in several plant species, little is known about comprehensive...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7717/peerj.3400
65 downloads
215 views

Although C-type cytoplasmic male sterility (CMS-C) is one of the most attractive tools for maize hybrid seed production, the detailed regulation network of the male sterility remains unclear. In order to identify the CMS-C sterility associated genes and/or pathways,...

["Agricultural Science","Genetics","Genomics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.3408

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