205 downloads
1,186 views

Summary: Clustered regularly interspaced palindromic repeat (CRISPR) systems are prokaryotic adaptive immune systems against viral infection. CRISPR spacer sequences can provide valuable ecological insights by linking environmental viruses to microbial hosts. Despite...

["Bioinformatics","Genomics","Microbiology","Computational Science"]
doi:10.7287/peerj.preprints.2278v3

As nontraditional model organisms with extreme physiological and morphological phenotypes, snakes are believed to possess an inferior taste system. However, the bitter taste sensation is essential to distinguish the nutritious and poisonous food resources and the...

["Evolutionary Studies","Genetics","Genomics","Zoology"]
doi:10.7717/peerj.3708
17 downloads
86 views

The prevalence of Type II Diabetes (T2D) has been increasing and has become a disease of significant public health burden in Jordan. None of the previous genome-wide association studies (GWAS) have specifically investigated the Middle East populations. The Circassian...

["Genetics","Genomics","Diabetes and Endocrinology","Medical Genetics"]
doi:10.7717/peerj.3618
16 downloads
92 views

The cynomolgus macaque (Macaca fascicularis) is an extensively utilised nonhuman primate model for biomedical research due to its biological, behavioural, and genetic similarities to humans. Genomic information of cynomolgus macaque is vital for research in various...

["Bioinformatics","Genomics","Zoology","Immunology"]
doi:10.7717/peerj.3566
10 downloads
133 views

Recently, a novel phenomenon of horizontal gene transfer of helicase-encoding sequence from positive-stranded RNA viruses to LINE transposons in insect genomes was described. TRAS family transposons encoding an ORF2 protein, which comprised all typical functional...

["Entomology","Genomics","Molecular Biology","Virology"]
doi:10.7717/peerj.3673
7 downloads
51 views

Background. Enteroviruses are small non-enveloped viruses with (+) ssRNA genome with one open reading frame. Enterovirus protein 3C (or 3CD for some species) binds replicative element oriL to initiate replication. The replication of enteroviruses features low fidelity...

["Evolutionary Studies","Genomics","Virology"]
doi:10.7287/peerj.preprints.3153v1
38 downloads
314 views

As coral reef habitats decline worldwide, some reefs are transitioning from coral- to algal-dominated benthos with the exact cause for this shift remaining elusive. Increases in the abundance of microbes in the water column has been correlated with an increase...

["Biodiversity","Ecology","Genomics","Marine Biology","Microbiology"]
doi:10.7717/peerj.3666
28 downloads
326 views

Gene Co-expression Network Analysis (GCNA) is a popular approach to analyze a collection of gene expression profiles. GCNA yields an assignment of genes to gene co-expression modules, a list of gene sets statistically over-represented in these modules, and a gene-to-gene...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.3678
22 downloads
103 views

Calcineurin B-like (CBL) proteins, as calcium sensors, play pivotal roles in plant responses to diverse abiotic stresses and in growth and development through interaction with CBL-interacting protein kinases (CIPKs). However, knowledge about functions and evolution...

["Evolutionary Studies","Genomics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.3653
12 downloads
56 views

Phylogeographic analyses of the gall fly Urophora cardui have in earlier studies based on allozymes and mtDNA identified small-scale, parapatrically diverged populations within an expanding Western Palearctic population. However, the low polymorphism of these markers...

["Biodiversity","Entomology","Evolutionary Studies","Genomics"]
doi:10.7717/peerj.3582
8 downloads
91 views

While the benefits of undergraduate research experiences (UREs) are recognized for undergraduates, the advantages of UREs for graduate students, post-doctoral scholars, and faculty are not clearly outlined. The analysis of genomic data is particularly well-suited...

["Bioinformatics","Genomics","Science and Medical Education"]
doi:10.7287/peerj.preprints.3149v1
11 downloads
139 views

We previously demonstrated how CITED1 knockdown in melanoma cells had the capacity to perturb expression of a significant number of genes that comprised MITF and several of its known transcriptional targets. This manifest as a switch from a more invasive to a more...

["Cell Biology","Genomics","Molecular Biology","Oncology"]
doi:10.7287/peerj.preprints.3146v1
58 downloads
428 views

The family Miridae is one of the most species-rich families of insects. To better understand the diversity and evolution of mirids, we determined the mitogenome of Lygus pratenszs and re-sequenced the mitogenomes of four mirids (i.e., Apolygus lucorum, Adelphocoris...

["Entomology","Evolutionary Studies","Genomics"]
doi:10.7717/peerj.3661
29 downloads
103 views

We report here the successful assembly of the complete mitochondrial genomes of the northern spotted owl (Strix occidentalis caurina) and the barred owl (S. varia). We utilized sequence data from two sequencing methodologies, Illumina paired-end sequence data with...

["Genetics","Genomics","Molecular Biology","Zoology"]
doi:10.7287/peerj.preprints.3120v1
61 downloads
594 views

The squid Sthenoteuthis oualaniensis, formerly Symplectoteuthis oualaniensis, generates light using the luciferin coelenterazine and a unique enzyme, symplectin. Genetic information is limited for bioluminescent cephalopod species, so many proteins, including symplectin,...

["Biochemistry","Evolutionary Studies","Genomics","Marine Biology"]
doi:10.7717/peerj.3633

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