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genomics
34 downloads
168 views

An uncultured non-photosynthetic basal lineage of the Cyanobacteria, the Melainabacteria, was recently characterised by metagenomic analyses of aphotic environmental samples. However, a predatory bacterium, Vampirovibrio chlorellavorus, originally described in...

["Genomics","Microbiology"]
doi:10.7717/peerj.968
796 downloads
1,099 views

Large-scale recovery of genomes from isolates, single cells, and metagenomic data has been made possible by advances in computational methods and substantial reductions in sequencing costs. While this increasing breadth of draft genomes is providing key information...

["Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.554v2
17 downloads
75 views

Objective. Bringing together genomics, transcriptomics, proteomics, and other -omics technologies is an important step towards developing highly personalized medicine. However, instrumentation has advances far beyond expectations and now we are able to generate...

["Computational Biology","Genetics","Genomics","Computational Science"]
doi:10.7717/peerj.970
180 downloads
940 views

The sequencing, assembly, and basic analysis of microbial genomes, once a painstaking and expensive undertaking, has become much easier for research labs with access to standard molecular biology and computational tools. However, there are a confusing variety of...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7717/peerj.960
16 downloads
20 views

For tissues to carry out their functions, they rely on the right proteins to be present. Several high-throughput technologies have been used to map out which proteins are expressed in which tissues; however, the data have not previously been systematically compared...

["Computational Biology","Genomics"]
doi:10.7287/peerj.preprints.1072v1
45 downloads
49 views

Transporter-facilitated arsenite extrusion is the major pathway of arsenic resistance within bacteria. So far only two types of membrane-bound transporter proteins, ArsB and ArsY (ACR3), have been well studied, although the arsenic transporters in bacteria display...

["Biochemistry","Bioinformatics","Genetics","Genomics"]
doi:10.7717/peerj.943
9 downloads
35 views

Chemotherapy is the mainstay in cancer treatment. Nevertheless, divergence of treatment responses exists across patients, often with the underlying mechanisms unknown. More disturbingly, some patients exhibits worsened outcome upon treatment. Genomic approaches...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v1
48 downloads
252 views

Falling costs in genomic laboratory experiments have led to a steady increase of genomic feature and variation data. Multiple genomic data formats exist for sharing these data, and whilst they are similar, they are addressing slightly different data viewpoints...

["Bioinformatics","Genetics","Genomics","Computational Science"]
doi:10.7717/peerj.933
39 downloads
61 views

Over the last decade, the emergence of high-throughput sequencing has led to an increase in both the size and scope of genome sequencing projects. Although genome sequencing and analysis has changed dramatically during this time, the way read alignments are visualised...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.1038v1
51 downloads
118 views

Contiguity is an interactive software for the visualization and manipulation of de novo genome assemblies. Contiguity creates and displays information on contig adjacency which is contextualized by the simultaneous display of a comparison between assembled contigs...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.1037v1
39 downloads
62 views

Vibrio variabilis strain T01 was isolated from the coastal waters in Hulu Selangor, Malaysia and its genome sequenced. This curved gram-negative bacterium shows cell-to-cell communication properties. The characteristics of the sequenced genome and its annotation...

["Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.1029v1
24 downloads
57 views

Objective: Bringing together genomics, transcriptomics, proteomics, and other –omics technologies is an important step towards developing highly personalized medicine. However, instrumentation has advances far beyond expectations and now we are able to generate...

["Computational Biology","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.1021v1
36 downloads
79 views

Streptococcus pneumoniae serotype 1 is one of the leading causes of invasive pneumococcal disease. However, this invasive serotype is hardly found in nasopharyngeal asymptomatic carriage and therefore large epidemiological studies are needed to assess the dynamics...

["Genomics","Microbiology","Epidemiology","Global Health","Infectious Diseases"]
doi:10.7717/peerj.903
39 downloads
85 views

Alternative splicing enables a single gene to produce multiple mRNA isoforms by varying splice site selection. In animals, alternative splicing of mRNA isoforms between cell types is widespread and supports cellular differentiation. In plants, at least 20% of multi-exon...

["Bioinformatics","Genomics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.919
70 downloads
224 views

Comparing inferences among datasets generated using short read sequencing may provide insight into the concerted impacts of divergence, gene flow and selection across organisms, but comparisons are complicated by biases introduced during dataset assembly. Sequence...

["Bioinformatics","Evolutionary Studies","Genetics","Genomics","Molecular Biology"]
doi:10.7717/peerj.895

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