12 downloads
104 views

Background Oral tongue squamous cell carcinoma (OTSCC) is the most common subtype of oral cancer. A predictive gene signature is necessary for prognosis of OTSCC. Methods Five microarray data sets of OTSCC from the Gene Expression Omnibus (GEO) and one data set...

["Bioinformatics","Computational Biology","Genetics","Genomics","Oncology"]
doi:10.7717/peerj.4062
107 downloads
509 views

The ascomycete pathogen Sclerotinia sclerotiorum is a necrotrophic pathogen on over 400 known host plants, and is the causal agent of white mold on dry bean. Currently, there are no known cultivars of dry bean with complete resistance to white mold. For more than...

["Agricultural Science","Genetics","Mycology"]
doi:10.7287/peerj.preprints.3311v2
33 downloads
152 views

The presence of acetic acid during industrial alcohol fermentation reduces the yield of fermentation by imposing additional stress on the yeast cells. The biology of cellular responses to stress has been a subject of vigorous investigations. Although much has been...

["Cell Biology","Genetics","Molecular Biology"]
doi:10.7717/peerj.4037
53 downloads
604 views

Background Currently, there is limited knowledge about the genetics underlying pigmentary traits in East Asian populations. Here, we report the results of the first genome-wide association study of pigmentary traits (skin and iris color) in individuals of East...

["Anthropology","Evolutionary Studies","Genetics","Genomics"]
doi:10.7717/peerj.3951
33 downloads
121 views

Background. Native meliponines are currently threatened by increased human impacts. The assessment of their genetic variation by microsatellite DNA markers can assist in the conservation of populations and help in the planning and establishment of efficient management...

["Biodiversity","Conservation Biology","Ecology","Entomology","Genetics"]
doi:10.7287/peerj.preprints.3382v1
21 downloads
169 views

The spindle pole body (SPB) in fungi is the equivalent of the animal centrosome. A number of previous studies have identified many, if not all, components of the SPB. The SPB is the structural platform for microtubule nucleation and plays important roles, both...

["Cell Biology","Genetics"]
doi:10.7287/peerj.preprints.3377v1
44 downloads
99 views

The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was heralded as a major breakthrough of the decade in stem cell research. The ability to reprogrammed human somatic cells to a pluripotent embryonic stem cell-like state through...

["Cell Biology","Developmental Biology","Genetics"]
doi:10.7287/peerj.preprints.3374v1
75 downloads
253 views

Structural equation modeling (SEM) is an important research tool, both for path-based model specification, common in the social sciences, and also matrix-based models in heavy use in behavior genetics. We developed umx to give more immediate access, concise syntax...

["Genetics","Psychiatry and Psychology","Science and Medical Education","Statistics"]
doi:10.7287/peerj.preprints.3354v1
109 downloads
289 views

Background/Aim Strabismus is a common condition with misalignment between two eyes that may lead to decrease of visual acuity, lack of binocularity, and diplopia. It is caused by heterogeneous environmental and genetic risk factors. Our previous research has identified...

["Genetics","Genomics","Ophthalmology","Medical Genetics"]
doi:10.7717/peerj.3935
76 downloads
263 views

Nosema apis and Nosema ceranae are the two main microsporidian parasites causing nosematosis in honey bee Apis mellifera. The object of the present study is to investigate the presence of Nosema apis and Nosema ceranae in the Bulgarian honey bee. The 16S (SSU)...

["Entomology","Genetics","Parasitology","Veterinary Medicine"]
doi:10.7287/peerj.preprints.3342v1
54 downloads
161 views

Many plant species exhibit heterophylly, displaying different leaves upon a single plant. The molecular mechanisms regulating this phenomenon, however, have remained elusive. In this study, the transcriptomes of submerged and floating leaves of an aquatic heterophyllous...

["Cell Biology","Developmental Biology","Evolutionary Studies","Genetics","Plant Science"]
doi:10.7287/peerj.preprints.3336v1
86 downloads
295 views

Background Hybrids possess phenotypic traits that are often intermediate between their parental taxa, which commonly serves as evidence of hybridization in morphological analyses. Natural hybridization has been shown to occur frequently in Ligularia (Asteraceae)....

["Evolutionary Studies","Genetics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.3884
84 downloads
356 views

We report here the successful assembly of the complete mitochondrial genomes of the northern spotted owl (Strix occidentalis caurina) and the barred owl (S. varia). We utilized sequence data from two sequencing methodologies, Illumina paired-end sequence data with...

["Genetics","Genomics","Molecular Biology","Zoology"]
doi:10.7717/peerj.3901
75 downloads
295 views

Background The honey bee (Apis mellifera) is a highly diverse species commonly used for honey production and pollination services. The oviposition of the honey bee queen affects the development and overall performance of the colony. To investigate the ovary activation...

["Agricultural Science","Bioinformatics","Entomology","Genetics"]
doi:10.7717/peerj.3881
95 downloads
889 views

Although the invasive azooxanthellate corals Tubastraea coccinea and T. tagusensis are spreading quickly and outcompeting native species in the Atlantic Ocean, there is little information regarding the genetic structure and path of introduction for these species....

["Biodiversity","Conservation Biology","Ecology","Genetics","Marine Biology"]
doi:10.7717/peerj.3873

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