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genetics
63 downloads
39 views

Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In dogs, dilated...

["Bioinformatics","Genetics","Veterinary Medicine","Cardiology","Medical Genetics"]
doi:10.7717/peerj.842
18 downloads
36 views

Background. The clade Chelidae (Testudines, Pleurodira) is a group of fresh water turtles with representatives in Australasia and South America. Its diversity of extant and fossil species is characterized by two recognized morphotypes: the long-necked and the short-necked...

["Bioinformatics","Evolutionary Studies","Genetics","Taxonomy"]
doi:10.7287/peerj.preprints.930v1
19 downloads
70 views

Natural selection, the most important force in evolution, comes in three forms. Negative purifying selection removes deleterious variation and maintains adaptations. Positive directional selection fixes beneficial variants, producing new adaptations. Balancing...

["Aquaculture, Fisheries and Fish Science","Evolutionary Studies","Genetics","Marine Biology","Immunology"]
doi:10.7287/peerj.preprints.924v1
19 downloads
41 views

Obesity is a major public health concern. This condition results from a constant and complex interplay between predisposing genes and environmental stimuli. Current attempts to manage obesity have been moderately effective and a better understanding of the etiology...

["Genetics","Diabetes and Endocrinology"]
doi:10.7717/peerj.856
29 downloads
139 views

Introduction: All the plants of a maize population or hybrid PP (plant population) do not dehisce anthers and do not emerge silk simultaneously. Generally, male flowering or anther dehiscence (anthesis) is leading and female flowering (silk emergence or silking)...

["Agricultural Science","Genetics","Plant Science"]
doi:10.7287/peerj.preprints.897v2
9 downloads
52 views

Introduction: Plant breeders are in search of marker trait for high grain yielding genotypes or hybrids or populations in cross pollinating crop species like maize. Leaves that stay green long have been found grain yield attributing. But, recent studies have depicted...

["Agricultural Science","Genetics","Plant Science"]
doi:10.7287/peerj.preprints.920v1
70 downloads
230 views

A distinguishing characteristic of genes that code for the major histocompatibility complex (MHC) is that alleles often share more similarity between, rather than within species. There are two likely mechanisms that can explain this pattern: convergent evolution...

["Evolutionary Studies","Genetics","Molecular Biology","Zoology","Immunology"]
doi:10.7717/peerj.853
16 downloads
10 views

Despite the long debate of whether or not multiple mating benefits the offspring, studies still show contradicting results. Multiple mating takes time and energy. Thus, if females fertilize their eggs with a single mating, why to mate more than once? We investigated...

["Biodiversity","Conservation Biology","Genetics","Marine Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.901v1
692 downloads
5,691 views

Although brain imaging studies have demonstrated that listening to music alters human brain structure and function, the molecular mechanisms mediating those effects remain unknown. With the advent of genomics and bioinformatics approaches, these effects of music...

["Genetics","Genomics"]
doi:10.7717/peerj.830
29 downloads
15 views

Silene ciliata Pourr. (Caryophyllaceae) is a species with a highly disjunct distribution that inhabits the alpine mountains of the Mediterranean Basin. We investigated the phylogeny and phylogeography of the species in an attempt to a) clarify the long suggested...

["Biogeography","Evolutionary Studies","Genetics","Plant Science","Taxonomy"]
doi:10.7287/peerj.preprints.889v1
142 downloads
209 views

A distinguishing characteristic of genes that code for the major histocompatibility complex (MHC) is that alleles often share more similarity between, rather than within species. There are two likely mechanisms that can explain this pattern: convergent evolution...

["Evolutionary Studies","Genetics","Molecular Biology","Zoology","Immunology"]
doi:10.7287/peerj.preprints.621v2
50 downloads
54 views

Genomic imprinting is the differential expression of alleles, with the expression being dependent upon the sex of the parent from which it was inherited. Hymenopteran insects (ants, bees and wasps) are emerging as potential models for genomic imprinting and epigenetics....

["Entomology","Evolutionary Studies","Genetics","Zoology"]
doi:10.7287/peerj.preprints.878v1
49 downloads
183 views

Evolutionary timescales can be estimated from genetic data using the molecular clock, often calibrated by fossil or geological evidence. However, estimates of molecular rates in mitochondrial DNA appear to scale negatively with the age of the clock calibration....

["Evolutionary Studies","Genetics","Molecular Biology"]
doi:10.7717/peerj.821
37 downloads
52 views

Substantial health disparities exist between African Americans and Caucasians in the United States. Copy number variations (CNVs) are one form of human genetic variations that have been linked with complex diseases and often occur at different frequencies among...

["Bioinformatics","Genetics","Genomics"]
doi:10.7717/peerj.677
105 downloads
410 views

Background. Most genetic disorders are caused by single nucleotide variations (SNVs) or small insertion/deletions (indels). High throughput sequencing has broadened the catalogue of human variation, including common polymorphisms, rare variations or disease causing...

["Bioinformatics","Genetics","Genomics"]
doi:10.7717/peerj.796

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