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Total of 11 results See all subject areas
diabetes and endocrinology

Background: Cardiovascular disease is a major cause of death in the western world. Regular physical activity is known to be highly beneficial for improving cardiovascular health status. Methods:The current abstract is based on the authors own data and a literature...

["Cell Biology","Diabetes and Endocrinology","Epidemiology","Kinesiology","Metabolic Sciences"]
doi:10.7287/peerj.preprints.367v1

We determined the effect of butyrate and other short-chain fatty acids (SCFA) on rates of lipolysis in 3T3-L1 adipocytes. Prolonged treatment with butyrate (5 mM) increased the rate of lipolysis approximately 2-3-fold. Aminobutyric acid and acetate had little or...

["Biochemistry","Cell Biology","Diabetes and Endocrinology","Metabolic Sciences"]
doi:10.7287/peerj.preprints.312v1

BACKGROUND: Several lines of evidence show that abdominal fat is strongly associated with insulin resistance and dysglycemia (impaired glucose tolerance - IGT or type 2 diabetes mellitus - T2DM). However, which component of abdominal fat, subcutaneous or intra-abdominal,...

["Diabetes and Endocrinology","Evidence Based Medicine","Internal Medicine","Metabolic Sciences"]
doi:10.7287/peerj.preprints.199v1

Aging is mysterious with unknown managing patterns. A surprising finding on the tune mode of autophagy by S-nitrosylation is a distinctive step towards the interpretation of the mechanism underlying aging and age-related diseases. This commentary article will discuss,...

["Cell Biology","Diabetes and Endocrinology","Metabolic Sciences","Neurology","Pathology"]
doi:10.7287/peerj.preprints.121v1

Background. This study’s goal was to provide dose–response data for a dopamine agonist in the baboon using standard methods (replicate measurements at each dose, across a range of doses), as a standard against which to subsequently validate a novel pharmacological...

["Neuroscience","Diabetes and Endocrinology","Pharmacology","Radiology and Medical Imaging"]
doi:10.7717/peerj.195

Background: This study’s goal was to provide dose-response data for a dopamine agonist in the baboon using standard methods (replicate measurements at each dose, across a range of doses), as a standard against which to subsequently validate a novel pharmacological...

["Neuroscience","Diabetes and Endocrinology","Pharmacology","Radiology and Medical Imaging"]
doi:10.7287/peerj.preprints.72v2

Insulin secretion from pancreatic β-cells plays an essential role in blood glucose homeostasis and type 2 diabetes. Many genes are involved in the secretion of insulin and most of these genes can be targeted by microRNAs (miRNAs). However, the role of miRNAs in...

["Genomics","Diabetes and Endocrinology"]
doi:10.7717/peerj.162

Aim. To provide bone status assessment in infancy using quantitative ultrasound (QUS) applied to second metacarpus.Methods. 103 healthy term infants and 3 patients with rickets, aged ≤ 12 months, underwent metacarpal QUS evaluation using QUS DBM Sonic Aurora IGEA...

["Biophysics","Diabetes and Endocrinology","Metabolic Sciences","Nutrition","Pediatrics"]
doi:10.7717/peerj.141

The gonadotropin releasing hormone (GnRH) system in the hypothalamus is often considered the final point in integration of environmental cues as they pertain to the reproductive axis. However, cues such as stress and food availability are detectable in the plasma...

["Ecology","Zoology","Diabetes and Endocrinology"]
doi:10.7717/peerj.139

Introduction. The objective of this study was to create a tool that accurately predicts the risk of morbidity and mortality in patients with type 2 diabetes according to an oral hypoglycemic agent.Materials and Methods. The model was based on a cohort of 33,067...

["Diabetes and Endocrinology","Epidemiology"]
doi:10.7717/peerj.87

Objectives. Diabetes mellitus (DM) and hypothyroidism are each associated with increased rate of pregnancy complications. However, their combined morbidity during gestation is poorly studied. Therefore, the aims of this study were to determine the prevalence of...

["Diabetes and Endocrinology","Gynecology and Obstetrics"]
doi:10.7717/peerj.52

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