Identification of appropriate reference genes (RGs) is critical to accurate data interpretation in quantitative real-time PCR (qPCR) experiments. In this study, we have utilised next generation RNA sequencing (RNA-seq) to analyse the transcriptome of a panel of...

["Genomics","Molecular Biology","Dermatology","Oncology","Medical Genetics"]
doi:10.7717/peerj.3631
7 downloads
85 views

According to our clinical experience, cellulitis is common in summer; however, very few studies have mentioned this trend. Using Google Trends, we analyzed the monthly data of Google searches for ‘cellulitis’ from 31 countries on six continents. Seasonality explained...

["Dermatology","Epidemiology","Global Health","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.3124v1
67 downloads
237 views

Background Quercus infectoria G. Olivier (Fagaceae) nutgalls have been widely employed in traditional Asian medicine for several treatments, especially wounds and skin disorders. However, the effects of this plant on wound healing have not yet been clearly elucidated....

["Dermatology","Diabetes and Endocrinology","Evidence Based Medicine"]
doi:10.7717/peerj.3608
42 downloads
313 views

Background 2′–4′ Dinitrofluorobenzene (DNFB) induced contact hypersensitivity is an established model of contact sensitivity and leukocyte migration. Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) deficient mice were used to examine the role of PECAM-1...

["Cell Biology","Dermatology","Immunology"]
doi:10.7717/peerj.3555
42 downloads
263 views

Background There is currently no study that has evaluated the differences in epidemiological and clinical characteristics among rosacea patients according to different facial sites. Methods Clinical and demographic data were obtained from 586 rosacea patients....

["Dermatology","Epidemiology","Pharmacology"]
doi:10.7717/peerj.3527
10 downloads
270 views

BACKGROUND: 2’-4’ Dinitrofluorobenzene (DNFB) induced contact hypersensitivity is an established model of contact sensitivity and leukocyte migration. Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) deficient mice were used to examine the role of PECAM-1...

["Cell Biology","Dermatology","Immunology"]
doi:10.7287/peerj.preprints.2947v2
1 citation
2,060 downloads
13,229 views

Importance Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers’ full prescribing information (FPI) for finasteride and dutasteride state that risk...

["Dermatology","Epidemiology","Internal Medicine","Pharmacology","Urology"]
doi:10.7717/peerj.3020
161 downloads
811 views

It has previously been shown that domestic dogs and their household owners share bacterial populations, and that sharing of bacteria between humans is facilitated through the presence of dogs in the household. However, less is known regarding the bacterial communities...

["Microbiology","Veterinary Medicine","Dermatology"]
doi:10.7717/peerj.3075
185 downloads
952 views

Localized genomic variability is crucial for the ongoing conflicts between infectious microbes and their hosts. An understanding of evolutionary and adaptive patterns associated with genomic variability will help guide development of vaccines and antimicrobial...

["Microbiology","Dermatology"]
doi:10.7717/peerj.2959
140 downloads
490 views

Background Multiple myeloma is a cancer which has a high occurrence rate and causes great injury to people worldwide. In recent years, many studies reported the effects of miRNA on the appearance of multiple myeloma. However, due to the differences of samples and...

["Genomics","Dermatology","Oncology"]
doi:10.7717/peerj.2831
1 citation
105 downloads
428 views

The incidence of cutaneous melanoma (CM) has rapidly increased over the past four decades. CM is often overlooked in East Asian populations due to its low incidence, despite East Asia making up 22% of the world’s population. Since the 1990s, Caucasian populations...

["Dermatology","Epidemiology","Oncology","Public Health"]
doi:10.7717/peerj.2809
196 downloads
702 views

Objective The skin is an important immunological barrier of the body as well as an optimal route for vaccine administration. Gua Sha, which involves press-stroke treatment of the skin, is an effective folk therapy, widely accepted in East Asia, for various symptoms;...

["Dermatology","Immunology"]
doi:10.7717/peerj.2451
176 downloads
387 views

In aggressive solid tumors like melanoma, a strategy for therapy personalization can be achieved by combining high-throughput data on the patient’s specific tumor mutation and expression profiles. A remarkable case is dendritic cell-based immunotherapy, where tumor...

["Bioinformatics","Dermatology","Immunology"]
doi:10.7287/peerj.preprints.2385v1
222 downloads
506 views

Identification of appropriate reference genes (RGs) is critical to accurate data interpretation in quantitative real-time PCR (qPCR) experiments. In this study, we have utilised next generation RNA-sequencing (RNA-seq) to analyse the transcriptome of a panel of...

["Genomics","Molecular Biology","Dermatology","Oncology","Medical Genetics"]
doi:10.7287/peerj.preprints.2331v1
203 downloads
426 views

Background Global reports show that the antimicrobial-resistance of Propionibacterium acnes isolated from patients with acne vulgaris is becoming a large problem, making it necessary to find new therapeutic drugs. Methods In this study, 23 clinical isolates of...

["Microbiology","Dermatology","Infectious Diseases"]
doi:10.7287/peerj.preprints.2107v1

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