32 downloads
173 views

Objective The skin is an important immunological barrier of the body as well as an optimal route for vaccine administration. Gua Sha, which involves press-stroke treatment of the skin, is an effective folk therapy, widely accepted in East Asia, for various symptoms;...

["Dermatology","Immunology"]
doi:10.7717/peerj.2451
49 downloads
151 views

In aggressive solid tumors like melanoma, a strategy for therapy personalization can be achieved by combining high-throughput data on the patient’s specific tumor mutation and expression profiles. A remarkable case is dendritic cell-based immunotherapy, where tumor...

["Bioinformatics","Dermatology","Immunology"]
doi:10.7287/peerj.preprints.2385v1
48 downloads
238 views

Identification of appropriate reference genes (RGs) is critical to accurate data interpretation in quantitative real-time PCR (qPCR) experiments. In this study, we have utilised next generation RNA-sequencing (RNA-seq) to analyse the transcriptome of a panel of...

["Genomics","Molecular Biology","Dermatology","Oncology","Medical Genetics"]
doi:10.7287/peerj.preprints.2331v1
57 downloads
134 views

Background Global reports show that the antimicrobial-resistance of Propionibacterium acnes isolated from patients with acne vulgaris is becoming a large problem, making it necessary to find new therapeutic drugs. Methods In this study, 23 clinical isolates of...

["Microbiology","Dermatology","Infectious Diseases"]
doi:10.7287/peerj.preprints.2107v1
108 downloads
454 views

Skin diseases constitute an essential health and aesthetic problem in the elderly. The aim of the study was to evaluate the knowledge of the elderly residents of public nursing homes and participants of the University of the Third Age in Bialystok, Poland surrounding...

["Dermatology","Geriatrics","Public Health"]
doi:10.7717/peerj.2028
219 downloads
638 views

Background. Emerging research revealed the essential role of mitochondria in regulating stem/progenitor cell differentiation of neural progenitor cells, mesenchymal stem cells and other stem cells through reactive oxygen species (ROS), Notch or other signaling...

["Cell Biology","Developmental Biology","Dermatology","Pharmacology"]
doi:10.7717/peerj.1821
224 downloads
736 views

Background. Resveratrol is a natural polyphenol that exhibits anti-inflammatory effects. The aim of this study was to investigate the effects of resveratrol treatment on epithelium-derived cytokines and epithelial apoptosis in a murine model of atopic dermatitis-like...

["Allergy and Clinical Immunology","Dermatology","Immunology"]
doi:10.7717/peerj.1889
222 downloads
490 views

Background. Leprosy reactions are acute inflammatory episodes that occur mainly in the multibacillary forms of the disease. The reactions are classified as type 1 (reverse reaction) or type 2 (erythema nodosum leprosum). Leprosy-associated oxidative stress has...

["Dermatology","Infectious Diseases","Metabolic Sciences"]
doi:10.7717/peerj.1799
136 downloads
94 views

Background. Emerging researches revealed the essential role of mitochondria in regulating stem/progenitor cell differentiation of neural progenitor cells, mesenchymal stem cells and other stem cells through reactive oxygen species (ROS), Notch or other signaling...

["Cell Biology","Developmental Biology","Dermatology","Pharmacology"]
doi:10.7287/peerj.preprints.1769v1
1 citation
847 downloads
8,516 views

An ever expanding body of research investigates the human microbiome in general and the skin microbiome in particular. Microbiomes vary greatly from individual to individual. Understanding the factors that account for this variation, however, has proven challenging,...

["Ecology","Evolutionary Studies","Genomics","Microbiology","Dermatology"]
doi:10.7717/peerj.1605
122 downloads
484 views

Background. Nd:YAP laser is widely used to investigate the nociceptive and pain systems, generating perpetual and laser-evoked neurophysiological responses. A major procedural concern for the use of Nd:YAP laser stimuli in experimental research is the risk of skin...

["Neuroscience","Anaesthesiology and Pain Management","Dermatology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.1577
1 citation
160 downloads
618 views

Context. During the late 1990s, insecticide resistance had rendered a number of treatment products ineffective; some companies saw this as an opportunity to develop alternative types of treatment. We investigated the possibility that a surfactant-based lotion containing...

["Clinical Trials","Dermatology","Drugs and Devices","Nursing","Public Health"]
doi:10.7717/peerj.1368
1 citation
555 downloads
806 views

Tyrosinase is a well-known key enzyme in melanin biosynthesis and its inhibitors have become increasingly important because of their potential use as hypopigmenting agents. In the present study, the anti-melanogenic effect of aqueous and ethanolic extracts from...

["Biochemistry","Plant Science","Dermatology","Drugs and Devices"]
doi:10.7717/peerj.1305
501 downloads
295 views

["Anaesthesiology and Pain Management","Dermatology","Epidemiology"]
doi:10.7287/peerj.preprints.785v1
5 citations
687 downloads
1,718 views

Hair from different individuals can be distinguished by physical properties. Although some data exist on other species, examination of the individual molecular differences within the human hair shaft has not been thoroughly investigated. Shotgun proteomic analysis...

["Biochemistry","Biodiversity","Dermatology"]
doi:10.7717/peerj.506

Top subject areas - Articles & Preprints

Top subject areas - People

View all subject areas