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biophysics
8 downloads
11 views

The governing nonlinear steady equations for oxygen transport in a microfluidic channel are solved analytically. The Lagrange inversion theorem is used which admits complete integrable solutions in the channel. Considering a cell-rich and cell free region with...

["Biophysics","Cell Biology","Computational Biology","Mathematical Biology","Hematology"]
doi:10.7287/peerj.preprints.1003v1
18 downloads
56 views

In protein evolution, due to functional and biophysical constraints, the rates of amino acid substitution differ from site to site. Among the best predictors of site-specific rates are solvent accessibility and packing density. The packing density measure that...

["Biophysics","Computational Biology","Evolutionary Studies","Mathematical Biology"]
doi:10.7717/peerj.911
25 downloads
19 views

Due to alternative splicing the human ACTN1 gene codes for three different transcripts of α‑actinin; one isoform that is expressed only in the brain and two with a more general expression pattern. The sequence difference is located to the C-terminal domains and...

["Biochemistry","Biophysics"]
doi:10.7287/peerj.preprints.988v1
23 downloads
13 views

The steps of the DNA replication process remains to be clarified. Transcription factors are supposed to find their specific binding-sequence driven by epigenetic modifications and GpC islands. But then how can the replication machinery be able to find the promoters...

["Biophysics"]
doi:10.7287/peerj.preprints.950v1
28 downloads
147 views

Several competing aetiologies of developmental dyslexia suggest that the problems with acquiring literacy skills are causally entailed by low-level auditory and/or speech perception processes. The purpose of this study is to evaluate the diverging claims about...

["Biophysics","Developmental Biology","Neuroscience","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.837
42 downloads
64 views

Protein phosphorylation is one of the most important protein post-translational modifications and plays a role in numerous cellular processes including recognition, signaling and degradation. It can be studied experimentally by various methodologies, like employing...

["Bioinformatics","Biophysics","Computational Biology"]
doi:10.7287/peerj.preprints.916v1
23 downloads
66 views

Bacterial populations present in Hg-rich environments have evolved biological mechanisms to detoxify methylmercury and other organometallic mercury compounds. The most common resistance mechanism relies on the H+-assisted cleavage of the Hg-C bond of methylmercury...

["Biochemistry","Biophysics"]
doi:10.7287/peerj.preprints.909v1
44 downloads
70 views

Valveless, tubular pumps are widespread in the animal kingdom, but the mechanism by which these pumps generate fluid flow are often in dispute. Where the pumping mechanism of many organs was once described as peristalsis, other mechanisms, such as dynamic suction...

["Bioengineering","Biophysics","Computational Biology","Developmental Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.906v1
118 downloads
50 views

Many animals, including fish, can utilize both vision and the chemical senses in intra-specific communication. However, the relative influence of these sensory modalities on behavioral and physiological responses in social interactions is not well understood. The...

["Animal Behavior","Biophysics","Ecology"]
doi:10.7287/peerj.preprints.880v1
89 downloads
493 views

Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins. In an earlier study we obtained crystals of murine norovirus (MNV) NS6 protease in which...

["Biochemistry","Biophysics","Molecular Biology","Virology"]
doi:10.7717/peerj.798
93 downloads
350 views

Mercury (Hg) is a bioaccumulating trace metal that globally circulates the atmosphere and waters in its elemental, inorganic and organic chemical forms. While Hg represents a notorious neurotoxicant, the underlying cellular pathways are insufficiently understood....

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Molecular Biology"]
doi:10.7717/peerj.754
50 downloads
63 views

We report a method to cause cell death by remotely heating microparticles by induction heating, this technique could be used to remove vascular deposits and thrombosis. In this preliminary work, we used micrometer size spherical (ferromagnetic) particles and (pure)...

["Bioengineering","Biophysics","Drugs and Devices","Translational Medicine"]
doi:10.7287/peerj.preprints.815v1
94 downloads
165 views

Introduction. It is well known that resolution on a gamma camera varies as a function of distance, scatter and the camera’s characteristics (collimator type, crystal thickness, intrinsic resolution etc). Manufacturers frequently provide only a few pre-calculated...

["Bioengineering","Biophysics","Radiology and Medical Imaging"]
doi:10.7717/peerj.722
329 downloads
244 views

Concurrent decision-making model (CDM) of interaction networks with more than two antagonistic components represents various biological systems, such as gene interaction, species competition and mental cognition. The CDM model assumes sigmoid kinetics where every...

["Bioinformatics","Biophysics","Computational Biology","Mathematical Biology","Computational Science"]
doi:10.7287/peerj.preprints.382v3
67 downloads
62 views

Mercury (Hg) is a bioaccumulating trace metal that globally circulates the atmosphere and waters in its elemental, inorganic and organic chemical forms. While Hg represents a notorious neurotoxicant, the underlying cellular pathways are insufficiently understood....

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.801v1

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