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biophysics
32 downloads
145 views

Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins. In an earlier study we obtained crystals of murine norovirus (MNV) NS6 protease in which...

["Biochemistry","Biophysics","Molecular Biology","Virology"]
doi:10.7717/peerj.798
59 downloads
209 views

Mercury (Hg) is a bioaccumulating trace metal that globally circulates the atmosphere and waters in its elemental, inorganic and organic chemical forms. While Hg represents a notorious neurotoxicant, the underlying cellular pathways are insufficiently understood....

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Molecular Biology"]
doi:10.7717/peerj.754
26 downloads
49 views

We report a method to cause cell death by remotely heating microparticles by induction heating, this technique could be used to remove vascular deposits and thrombosis. In this preliminary work, we used micrometer size spherical (ferromagnetic) particles and (pure)...

["Bioengineering","Biophysics","Drugs and Devices","Translational Medicine"]
doi:10.7287/peerj.preprints.815v1
57 downloads
133 views

Introduction. It is well known that resolution on a gamma camera varies as a function of distance, scatter and the camera’s characteristics (collimator type, crystal thickness, intrinsic resolution etc). Manufacturers frequently provide only a few pre-calculated...

["Bioengineering","Biophysics","Radiology and Medical Imaging"]
doi:10.7717/peerj.722
301 downloads
228 views

Concurrent decision-making model (CDM) of interaction networks with more than two antagonistic components represents various biological systems, such as gene interaction, species competition and mental cognition. The CDM model assumes sigmoid kinetics where every...

["Bioinformatics","Biophysics","Computational Biology","Mathematical Biology","Computational Science"]
doi:10.7287/peerj.preprints.382v3
56 views

Mercury (Hg) is a bioaccumulating trace metal that globally circulates the atmosphere and waters in its elemental, inorganic and organic chemical forms. While Hg represents a notorious neurotoxicant, the underlying cellular pathways are insufficiently understood....

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.801v1
59 downloads
59 views

This thesis describes the work that has been carried out in connection with my Masters at the University of Copenhagen. This work has led to new dispersion and hydrogen bond corrections to the PM6 method, PM6-D3H+, and its implementation in the GAMESS program....

["Biochemistry","Biophysics","Drugs and Devices","Computational Science"]
doi:10.7287/peerj.preprints.799v1
55 downloads
62 views

In this preliminary effort, we use a commercially available and chemically modified tube to selectively capture circulating tumor cells (CTCs) from the blood stream by immobilizing human anti-EpCAM antibodies on the tube's interior surface. We describe the steps...

["Bioengineering","Biophysics","Drugs and Devices"]
doi:10.7287/peerj.preprints.793v1
31 downloads
17 views

We examine the possible role of 'noise' as a control signal for large-scale cognitive biological phenomena that recruit simpler cognitive modules into temporary, dynamic working coalitions. Noise color, as well as magnitude, may convey essential control information,...

["Biophysics","Mathematical Biology","Neuroscience"]
doi:10.7287/peerj.preprints.774v1
71 downloads
66 views

Background. Integration of reductionist and holistic approaches is one of the great challenges for mathematical modeling. Mathematical models of complex systems are divided into black-box, white-box and grey-box types. A black-box model is completely nonmechanistic...

["Biophysics","Computational Biology","Ecology","Mathematical Biology","Computational Science"]
doi:10.7287/peerj.preprints.762v1
73 downloads
34 views

Background: Datasets consisting of synthetic neural data generated with quantifiable and controlled parameters are a valuable asset in the process of testing and validating directed connectivity metrics. Considering the recent debate in the neuroimaging community...

["Biophysics","Neuroscience","Computational Science"]
doi:10.7287/peerj.preprints.737v1
178 downloads
140 views

A persistent challenge in materials science is the characterization of a large ensemble of heterogeneous nanostructures in a set of images. This often leads to practices such as manual particle counting, and sampling bias of a favorable region of the “best” image....

["Bioengineering","Biophysics","Biotechnology"]
doi:10.7287/peerj.preprints.671v2
188 downloads
128 views

The Mass, Metabolism and Length Explanation (MMLE) was advanced in 1984 to explain the relationship between metabolic rate and body mass for birds and mammals. This paper reports on a modernized version of MMLE. MMLE deterministically predicts the absolute value...

["Biophysics","Mathematical Biology","Zoology"]
doi:10.7287/peerj.preprints.437v3
47 downloads
159 views

Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins. In an earlier study we obtained crystals of murine norovirus (MNV) NS6 protease in which...

["Biochemistry","Biophysics","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.646v1
153 downloads
47 views

History is often thought to be dull and boring – where large numbers of facts are memorized for passing exams. But the past informs both the present and future; particularly in delineating the context surrounding specific events that, in turn, help provide us with...

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.552v1

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