Total of 1,035 results Filter on subject area
bioinformatics

Tandem repeat sequences have been found in great numbers in proteins that are conserved in a wide range of living species. In order to reconstruct the evolutionary history of such sequences, it is necessary to develop algorithms and methods that can work with highly...

["Bioinformatics","Computational Biology"]
doi:10.7717/peerj-cs.6

The growing number of genotyped populations, the advent of high-throughput phenotyping techniques and the development of GWAS analysis software has rapidly accelerated the number of GWAS experimental results. Candidate gene discovery from these results files is...

["Bioinformatics","Computational Biology","Visual Analytics"]
doi:10.7717/peerj-cs.3
53 downloads
180 views

Ghost-tree is a bioinformatics tool that integrates sequence data from two genetic markers into a single phylogenetic tree that can be used for diversity analyses. Our approach uses one genetic marker whose sequences can be aligned across organisms spanning divergent...

["Bioinformatics","Microbiology"]
doi:10.7287/peerj.preprints.1106v1
807 downloads
1,113 views

Large-scale recovery of genomes from isolates, single cells, and metagenomic data has been made possible by advances in computational methods and substantial reductions in sequencing costs. While this increasing breadth of draft genomes is providing key information...

["Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.554v2
5 downloads
19 views

MicroView was made to make the connection between medicine and mobile technology reality, in order to achieve that we transform the widely used mobile devices (smartphones, tablets) into diagnostic tools. MicroView is a medical application that focuses on the diagnosis...

["Bioinformatics","Microbiology","Infectious Diseases","Science and Medical Education"]
doi:10.7287/peerj.preprints.1096v1
15 downloads
13 views

Recently, survival ensembles have found more and more applications in biological and medical research when censored time-to-event data are often confronted. In this research, we investigate the plausibility of extending rotation forest, originally proposed for...

["Bioinformatics","Computational Biology","Statistics"]
doi:10.7287/peerj.preprints.1086v1
12 downloads
97 views

Dopamine is a major neurotransmitter in the human brain and is associated with various diseases. Schizophrenia, for example, is treated by blocking the dopamine receptors type 2. In 2009, Shaner, Miller and Mintz stated that schizophrenia was the low fitness variant...

["Anthropology","Bioinformatics","Evolutionary Studies","Genetics"]
doi:10.7287/peerj.preprints.1083v1
13 downloads
38 views

Background. Podocnemis bassleri Williams, 1956 is the oldest definite record for Podocnemis, dating back to the Miocene of South America. However, the diagnosis of P. ba. is fragile, as assumed by Williams himself. Here we evaluated the hypothesis of P. ba. as...

["Bioinformatics","Evolutionary Studies","Paleontology","Taxonomy","Zoology"]
doi:10.7287/peerj.preprints.1077v1
185 downloads
958 views

The sequencing, assembly, and basic analysis of microbial genomes, once a painstaking and expensive undertaking, has become much easier for research labs with access to standard molecular biology and computational tools. However, there are a confusing variety of...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7717/peerj.960
45 downloads
50 views

Transporter-facilitated arsenite extrusion is the major pathway of arsenic resistance within bacteria. So far only two types of membrane-bound transporter proteins, ArsB and ArsY (ACR3), have been well studied, although the arsenic transporters in bacteria display...

["Biochemistry","Bioinformatics","Genetics","Genomics"]
doi:10.7717/peerj.943
9 downloads
35 views

Chemotherapy is the mainstay in cancer treatment. Nevertheless, divergence of treatment responses exists across patients, often with the underlying mechanisms unknown. More disturbingly, some patients exhibits worsened outcome upon treatment. Genomic approaches...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v1
52 downloads
258 views

Falling costs in genomic laboratory experiments have led to a steady increase of genomic feature and variation data. Multiple genomic data formats exist for sharing these data, and whilst they are similar, they are addressing slightly different data viewpoints...

["Bioinformatics","Genetics","Genomics","Computational Science"]
doi:10.7717/peerj.933
39 downloads
61 views

Over the last decade, the emergence of high-throughput sequencing has led to an increase in both the size and scope of genome sequencing projects. Although genome sequencing and analysis has changed dramatically during this time, the way read alignments are visualised...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.1038v1
52 downloads
121 views

Contiguity is an interactive software for the visualization and manipulation of de novo genome assemblies. Contiguity creates and displays information on contig adjacency which is contextualized by the simultaneous display of a comparison between assembled contigs...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.1037v1
80 downloads
349 views

The origin of recent parallel outbreaks of the high pathogenicity H5N8 avian flu virus in Europe and in Japan can be traced to a single source population, which has most likely been spread by migratory birds. By using Bayesian coalescent methods to analyze the...

["Agricultural Science","Bioinformatics","Computational Biology","Genetics","Virology"]
doi:10.7717/peerj.934

Top subject areas - Articles & Preprints

Top subject areas - People

View all subject areas