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bioinformatics
15 downloads
6 views

This paper suggests a knew approach for analysing inactive phases in long term measurements using mobile accelerometry attached to a human body. The goal of the work is to provide a commandline tool to automaticaly parse a timestamped list of acceleration data...

["Bioengineering","Bioinformatics","Anatomy and Physiology","Computational Science"]
doi:10.7287/peerj.preprints.978v1
36 downloads
14 views

Many people prefer running to keep in shape. In recent years many self-tracking and self-optimization gadgets has become popular especially for running. We are interested in the quality of running because individual running style has an impact on the running performance...

["Bioengineering","Bioinformatics","Anatomy and Physiology","Orthopedics","Computational Science"]
doi:10.7287/peerj.preprints.976v1
54 downloads
36 views

CRISPR/Cas9 is emerging as one of the most used methods of genome modification in organisms ranging from bacteria to human cells. However, the efficiency of editing varies tremendously site-to-site. A recent report identified a novel motif, called the 3’GG motif,...

["Bioinformatics"]
doi:10.7287/peerj.preprints.969v1
42 downloads
99 views

The pyfaidx Python module provides memory and time-efficient indexing, subsetting, and in-place modification of subsequences of FASTA files. pyfaidx provides Python classes that expose a dictionary interface where sequences from an indexed FASTA can be accessed...

["Bioinformatics","Computational Biology"]
doi:10.7287/peerj.preprints.970v1
40 downloads
33 views

In a recent study, Murrell et al. (2015) compared the performance of several branch-site models of codon evolution. Their interpretation of results published by Lu & Guindon (2014) suggests that the stochastic branch-site model implemented in the software fitmodel...

["Bioinformatics","Evolutionary Studies"]
doi:10.7287/peerj.preprints.944v1
56 downloads
81 views

Despite the wealth of mental-health information available online to consumers, research has shown that the mental-health information needs of consumers are not being met. This study contributes to that research by soliciting consumer questions directly, categorizing...

["Bioinformatics","Cognitive Disorders","Psychiatry and Psychology","Public Health","Human\u2013Computer Interaction"]
doi:10.7717/peerj.867
94 downloads
659 views

Modern biological research requires rapid, complex, and reproducible integration of multiple experimental results generated both internally and externally (e.g., from public repositories). Although large systematic meta-analyses are among the most effective approaches...

["Bioinformatics","Computational Biology"]
doi:10.7717/peerj.791
46 downloads
33 views

The obesity epidemic is a worldwide problem. Studies from the late 20th century show a consistent trend of increasing obesity prevalence on a global scale (Popkin & Doak, 1998). The OECD reports that overweight and obese people are now a majority amongst OECD countries,...

["Bioengineering","Bioinformatics","Anatomy and Physiology","Global Health","Science and Medical Education"]
doi:10.7287/peerj.preprints.937v1
179 downloads
235 views

Background: Taxonomic classification of marker-gene (i.e., amplicon) sequences represents an important step for molecular identification of microorganisms.Results: We present three advances in our ability to assign and interpret taxonomic classifications of short...

["Bioinformatics","Computational Biology","Ecology","Microbiology","Taxonomy"]
doi:10.7287/peerj.preprints.934v1
174 downloads
638 views

Recently, a number of protocols extending RNA-sequencing to the single-cell regime have been published. However, we were concerned that the additional steps to deal with such minute quantities of input sample would introduce serious biases that would make analysis...

["Bioinformatics","Biotechnology","Computational Biology","Genomics"]
doi:10.7717/peerj.869
123 downloads
212 views

Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In dogs, dilated...

["Bioinformatics","Genetics","Veterinary Medicine","Cardiology","Medical Genetics"]
doi:10.7717/peerj.842
38 downloads
87 views

Background. The clade Chelidae (Testudines, Pleurodira) is a group of fresh water turtles with representatives in Australasia and South America. Its diversity of extant and fossil species is characterized by two recognized morphotypes: the long-necked and the short-necked...

["Bioinformatics","Evolutionary Studies","Genetics","Taxonomy"]
doi:10.7287/peerj.preprints.930v1
17 downloads
52 views

Mobile accelerometry is more and more being used in clinical trials as a tool to measure outcomes related to physical activity. However, it is still difficult to integrate exercise therapy in controlled clinical trials. We want to explore the option to use a unified...

["Bioengineering","Bioinformatics","Computational Science"]
doi:10.7287/peerj.preprints.929v1
8 downloads
16 views

The ”Gait-&Balance-Box” suggests a standardization for clinical walk and balance tests with the aim to improve quality, applicability and comparability. Heart of the patient monitoring is the actibeltblue, an autonomous wireless accelerometer that is worn like...

["Bioengineering","Bioinformatics","Evidence Based Medicine","Computational Science"]
doi:10.7287/peerj.preprints.928v1
62 downloads
77 views

Currently, monomeric fluorescent proteins (FP) are ideal markers for protein tagging. The prediction of oligomeric states is helpful for enhancing live biomedical imaging. Computational prediction of FP oligomeric states can accelerate the effort of protein engineering...

["Bioinformatics","Computational Biology"]
doi:10.7287/peerj.preprints.922v1

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