16 downloads
83 views

Increased levels of long noncoding RNA H19 (H19) have been observed in many inflammatory and organ fibrosis diseases including ulcerative colitis, osteoarthritis, liver fibrosis, renal fibrosis and pulmonary fibrosis. However, the role of H19 in bovine mastitis...

["Biochemistry","Cell Biology","Veterinary Medicine"]
doi:10.7717/peerj.3950
29 downloads
265 views

In the context of a hunt for a postulated hormone that is tissue-mass inhibiting and reproductively associated, there is described probable relatedness to a granin protein. A 7–8 kDa polypeptide candidate (gels/MS) appeared in a bioassay-guided fractionation campaign...

["Biochemistry","Cell Biology","Diabetes and Endocrinology","Neurology"]
doi:10.7717/peerj.3833
34 downloads
141 views

Background Aspergillus niger, along with many other lignocellulolytic fungi, has been widely used as a commercial workhorse for cellulase production. A fungal cellulase system generally includes three major classes of enzymes i.e., β-glucosidases, endoglucanases...

["Biochemistry","Biotechnology","Molecular Biology"]
doi:10.7717/peerj.3909
12 downloads
83 views

Background: Oxidative stress plays an important role in the pathogenesis of heart diseases. Antioxidants such as palm tocotrienol-rich fraction (TRF) can reduce oxidative stress, hence preventing and reducing the risk of heart disease. This study was aimed to determine...

["Biochemistry","Nutrition"]
doi:10.7287/peerj.preprints.3333v1
10 downloads
69 views

Transglutaminases (TGases) are a class of enzyme widely spread in nature, and observed in plants, microorganisms, vertebrates and invertebrates. This enzyme catalyzes post-translational protein modification, by acyl transfer reactions, deamidation and crosslinking...

["Biochemistry","Bioinformatics"]
doi:10.7287/peerj.preprints.3320v1
9 downloads
120 views

Quality disciplines have been widely used for decades in industrial and business fields. It is only in recent times, however, that Quality management and approaches have received proper attention in life science. The development, optimization, validation and dissemination...

["Biochemistry","Cell Biology","Developmental Biology","Ethical Issues","Science Policy"]
doi:10.7287/peerj.preprints.3316v1
39 downloads
374 views

Italian ryegrass (Lolium multiflorum) is an important cool-season, annual forage crop for the grassland rotation system in Southern China. The primary aim of breeding programs is always to seek to improve forage quality in the animal productivity system; however,...

["Agricultural Science","Biochemistry","Plant Science","Statistics"]
doi:10.7717/peerj.3867
59 downloads
296 views

The classification of Cannabis varieties has been increasingly discussed in the past years, particularly in the wake of emerging legal markets, with implications for intellectual property development, marketing and improvement of the scientific understanding of...

["Agricultural Science","Biochemistry","Biodiversity","Plant Science","Taxonomy"]
doi:10.7287/peerj.preprints.3307v1
68 downloads
330 views

Rapid proliferation and Warburg effect make cancer cells consume plenty of glucose, which induces a low glucose micro-environment within the tumor. Up to date, how cancer cells keep proliferating in the condition of glucose insufficiency still remains to be explored....

["Biochemistry","Cell Biology","Oncology"]
doi:10.7717/peerj.3804
20 downloads
69 views

Scale transcends multiple levels of biological and physical organization, and is the critical factor that determines success of any scientific investigation. Specifically, the scale at which a question is posed plays a crucial role in influencing the type of experiments...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Cell Biology"]
doi:10.7287/peerj.preprints.3261v1
74 downloads
232 views

Background Food selection and ingestion both in humans and rodents, often is a critical factor in determining excess energy intake and its related disorders. Methods Two different concepts of high-fat diets were tested for their obesogenic effects in rats; in both...

["Biochemistry","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.3697
10 downloads
73 views

Microfluidic cell culture chambers have enabled the isolation, culture and growth of various species of microorganisms and human cells. However, based on elastomers such as poly(dimethyl siloxane) (PDMS), these culture devices are not readily amenable to imaging...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3245v1
66 downloads
512 views

Energy buffering systems are key for homeostasis during variations in energy supply. Spiders are the most important predators for insects and therefore key in terrestrial ecosystems. From biomedical interest, spiders are important for their venoms and as a source...

["Biochemistry","Biophysics","Zoology","Allergy and Clinical Immunology"]
doi:10.7717/peerj.3787
6 downloads
99 views

Co-existence of microbes in a community is the de facto state of microbial lifestyle in almost all niches on Earth. Thus, microbes live with other microbial species in close proximity, and evolution has selected for specific methods of communication between microbes...

["Biochemistry","Biodiversity","Cell Biology","Ecology","Microbiology"]
doi:10.7287/peerj.preprints.3239v1
123 downloads
454 views

In recent years, the use of lectins for screening of potential biomarkers has gained increased importance in cancer research, given the development in glycobiology that highlights altered structural changes of glycans in cancer associated processes. Lectins, having...

["Biochemistry","Biotechnology","Oncology"]
doi:10.7717/peerj.3784

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