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Total of 195 results See all subject areas
statistics

In ChIP-Seq and DNase-Seq experiments the density of background reads can vary from sample to sample. Differences in background read densities between samples do not necessarily correspond to proportional changes of read densities in true ChIP-Seq peaks. Therefore,...

["Bioinformatics","Genomics","Neuroscience","Statistics"]
doi:10.7287/peerj.preprints.175v2

Overview. The Centers for Disease Control and Prevention (CDC) health-related quality of life (HRQoL) indicators are widely used in the general population to determine the burden of disease, identify health needs, and direct public health policy. These indicators...

["Epidemiology","Infectious Diseases","Statistics"]
doi:10.7717/peerj.322

The maximum likelihood estimation (MLE) method, typically used for polytomous logistic regression, is prone to bias due to both misclassification in outcome and contamination in the design matrix. Hence, robust estimators are needed. In this study, we propose such...

["Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.299v1

We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC). This estimation is non-trivial, as the data consist of ordinal measurements on 16...

["Genetics","Orthopedics","Statistics"]
doi:10.7287/peerj.preprints.284v1

For more than thirty years, it has been claimed that a way to improve software developers’ productivity and software quality is to focus on people and to provide incentives to make developers satisfied and happy. This claim has rarely been verified in software...

["Psychiatry and Psychology","Human\u2013Computer Interaction","Statistics"]
doi:10.7717/peerj.289

Two big cat skulls procured from hunters of Yanachaga National Park, Peru, were reported as those of cats informally dubbed the ‘striped tiger’ and ‘anomalous jaguar’. Observations suggested that both skulls were distinct from those of jaguars, associated descriptions...

["Taxonomy","Zoology","Statistics"]
doi:10.7717/peerj.291

Proficiency in mathematics and statistics is essential to modern ecological science, yet few studies have assessed the level of quantitative training received by ecologists. To do so, we conducted an online survey. The 937 respondents were mostly early-career scientists...

["Conservation Biology","Ecology","Environmental Sciences","Science and Medical Education","Statistics"]
doi:10.7717/peerj.285

Species traits may provide a short-cut to predicting generalities in species turnover in response to environmental change, particularly for poorly known taxa. We ask if morphological traits of assemblages respond predictably to macrohabitats across a large scale....

["Biodiversity","Ecology","Entomology","Zoology","Statistics"]
doi:10.7717/peerj.271

Sheng-Chia Chung and colleagues report in The Lancet (23 January 2014) an international comparison of cardiovascular patient mortality between the UK and Sweden. They suggest that “more than 10000 deaths at 30 days would have been prevented or delayed had UK patients...

["Cardiology","Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.253v1

To assess the efficacy of using eyeblink frequency modulation to detect deception about a third party, 32 participants were sent on a mission to deliver a package to an interviewer. 17 of the participants lied to the interviewer about the details of their mock...

["Psychiatry and Psychology","Human-Computer Interaction","Statistics"]
doi:10.7717/peerj.260

Connectance and degree distributions are important components of the structure of ecological networks. In this contribution, we use a statistical argument and simple network generating models to show that properties of the degree distribution are driven by network...

["Biodiversity","Ecology","Computational Science","Statistics"]
doi:10.7717/peerj.251

Identification of the majority of organisms present in human-associated microbial communities is feasible with the advent of high throughput sequencing technology. However, these data consist of non-negative, highly skewed sequence counts with a large proportion...

["Bioinformatics","Microbiology","Statistics"]
doi:10.7287/peerj.preprints.215v1

Partial least squares (PLS) have gained wide applications especially in chemometrics, metabolomics/metabonomics as well as bioinformatics. To our knowledge, an integrated PLS library that include not only basic PLS modeling algorithms but also advanced and/or recently...

["Bioinformatics","Computational Science","Statistics"]
doi:10.7287/peerj.preprints.190v1

Several clinical scoring systems for diagnosis of bovine respiratory disease (BRD) in calves have been proposed. However, such systems were based on subjective judgment, rather than statistical methods, to weight scores. Data from a pair-matched case-control study...

["Veterinary Medicine","Epidemiology","Statistics"]
doi:10.7717/peerj.238

Proficiency in mathematics and statistics is essential to modern ecological science, yet few studies have assessed the level of quantitative training received by ecologists. To do so, we conducted an online survey. The 937 respondents were mostly early-career scientists...

["Conservation Biology","Ecology","Environmental Sciences","Science and Medical Education","Statistics"]
doi:10.7287/peerj.preprints.53v2

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